Results 171 to 180 of about 3,678 (218)
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Cholestanol Metabolism, Molecular Pathology, and Nutritional Implications
Journal of Medicinal Food, 2003Cholestanol, not cholesterol, is a minor component in the human body and in foods, but an increase in cholestanol concentration in serum induces a pathological condition named cerebrotendinous xanthomatosis (CTX). In our investigation of this disease for more than 25 years, a procedure for quantification of cholestanol by high-performance liquid ...
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The metabolism of cholestanol in primary biliary cirrhosis
Journal of Hepatology, 1996The concentration of serum cholestanol, a 5 alpha-saturated derivative of cholesterol, is increased in primary biliary cirrhosis proportionally to impaired liver function for unknown reasons. The purpose of this study was to analyze serum cholestanol level and its biliary and fecal elimination, and relate the results to cholesterol absorption and ...
Helena Gylling
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Cholestanol Esters of Amino Acids
Bulletin of the Chemical Society of Japan, 1967Abstract The cholestanol (5α-cholestan-3β-ol) esters of amino acids were synthesized with an interest for their possible biochemical activities. The cholestanol esters of glycine, l-alanine, β-alanine, l-leucine and l-aspartic acid were synthesized by a direct fusion of the two components under the passing of hydrogen chloride through ...
Y, Matsumoto, M, Shirai, M, Minagawa
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Biosynthesis of cholestanol in higher plants
Phytochemistry, 2002To understand the early steps of C(27) brassinosteroid biosynthesis, metabolic experiments were performed with Arabidopsis thaliana and Nicotiana tabacum seedlings, and with cultured Catharanthus roseus cells. [26, 28-2H(6)]Campestanol, [26-2H(3)]cholesterol, and [26-2H(3)]cholestanol were administered to each plant, and the resulting metabolites were ...
Naoko, Nakajima +4 more
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Chromatographic separation of putative precursors of cholestanol
Steroids, 1988This paper describes convenient syntheses for labeled and unlabeled cholest-5-en-3-one, cholest-4-en-3-one, epicholesterol, cholest-4-en-3 beta-ol, and cholest-4-en-3 alpha-ol. The thin-layer chromatography, high-performance liquid chromatography, and gas-liquid chromatography of these compounds and of cholestanol and epicholestanol are also described.
A K, Batta, G, Salen, S, Shefer
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Cholestanol-Induced Gallstones: Radiologic Observations
Radiology, 1967Gallstones can be reliably induced in rabbits by the addition of 3-beta-cholestanol to an otherwise normal diet. This initial observation of Bevans and Mosbach (2) has been confirmed by others (3, 6, 8) and has been found to be a useful experimental model.
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Cholestanol Induces Apoptosis of Cerebellar Neuronal Cells
Biochemical and Biophysical Research Communications, 1999Cerebrotendinous xanthomatosis (CTX) is a hereditary lipid storage disease characterized by hyper-cholestanolemia, cerebellar ataxia, xanthoma, and cataract. We hypothesized that cholestanol in serum of CTX patients might induce neuronal cell death in the cerebellum and eventually lead to cerebellar ataxia.
K, Inoue, S, Kubota, Y, Seyama
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Squalene and cholestanol in normal rabbit aorta
Atherosclerosis, 1970Abstract Squalene and cholestanol were isolated from normal rabbit aortic tissue, identified and quantitatively determined. The concentration of squalene and cholestanol was 4.5 and 7.7 mg respectively, in 100 g of dry, delipidized tissue.
V, Stefanovich, G, Kajiyama
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Analysis of sterol extracts for cholestanol
Analytical Biochemistry, 1965Abstract Cholestanol analyses of sterols have been carried out by removal of the unsaturated sterols by oxidation and extraction followed by gas chromatography of the saturated sterols. The method can detect 0.2% of cholestanol in sterol mixtures.
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Effects of cholestanol feeding on corneal dystrophy in mice
Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, 1991A cholestanol-enriched diet administered for 8 months to BALB/c mice produced in 20% two kinds of corneal opacities resembling calcific band keratopathy and Schnyder's crystalline dystrophy in humans. The concentrations of cholestanol in serum, liver and cornea of the corneal opacity bearing mice were 30-40-times higher than those of normal mice.
K S, Kim +5 more
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