Results 171 to 180 of about 2,254 (206)
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Cholestanol Induces Apoptosis of Cerebellar Neuronal Cells
Biochemical and Biophysical Research Communications, 1999Cerebrotendinous xanthomatosis (CTX) is a hereditary lipid storage disease characterized by hyper-cholestanolemia, cerebellar ataxia, xanthoma, and cataract. We hypothesized that cholestanol in serum of CTX patients might induce neuronal cell death in the cerebellum and eventually lead to cerebellar ataxia.
K, Inoue, S, Kubota, Y, Seyama
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Cholestanol-Induced Gallstones: Radiologic Observations
Radiology, 1967Gallstones can be reliably induced in rabbits by the addition of 3-beta-cholestanol to an otherwise normal diet. This initial observation of Bevans and Mosbach (2) has been confirmed by others (3, 6, 8) and has been found to be a useful experimental model.
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Plasma Esterification of Cholestanol, Normally and in Cerebrotendinous Xanthomatosis
Scandinavian Journal of Clinical and Laboratory Investigation, 1974In vitro esterification of labeled cholestanol was demonstrated in normal plasma as well as in plasma from patients with cerebrotendinous xanthomatosis, the rate of esterification being about 70 per cent of that of cholesterol. In familial lecithin:cholesterol acyltransferase (LCAT) deficiency no esterification either of cholesterol or of cholestanol ...
S, Skrede, K T, Stokke
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Cholestanol and plant sterols in pigeon skin
Lipids, 1973AbstractCholestanol (4.6%) and plant sterols (0.2%) have been demonstrated, for the first time, in avian skin by argentation and gas liquid chromatography. In contrast to results of previous studies with rat and human skin, cholestanol represented a significant amount in the pigeon.
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Effect of Vagotomy on Cholestanol Cholelithogenesis in the Rabbit
Investigative Radiology, 1968The effect of bilateral truncal vagotomy on the gallbladder of the rabbit was studied. Up to twenty-four weeks, no significant spontaneous cholelithogenesis appeared. When vagotomized rabbits were given sublithogenic doses of cholestanol, gallstones formed in 50%.
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Gallstone formation in cholestanol-fed mice.
Journal of biochemistry, 1993We examined the effect of cholestanol (5 alpha-dihydrocholesterol) on cholesterol and bile acid metabolism in BALB/c mice. After feeding 1% cholestanol in the diet for 14 months, gallstones composed of 55% cholesterol and 45% cholestanol developed in 20% of the mice and were associated with mucosal inflammation and serosal vessel thickening of the ...
K S, Kim +5 more
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Studies on the biosynthesis of cholestanol in cultured cells.
Journal of biochemistry, 1983The presence of cholestanol had never been reported in cultured cells, but in the present study cholestanol was detected both in human and rat skin fibroblasts. The present study has shown that the origin of cholestanol in these fibroblasts was derived from de novo synthesis in the cells rather than from the fetal calf serum used in the growth medium ...
S, Serizawa +3 more
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Australian Journal of Experimental Biology and Medical Science, 1960
A Bolliger, D Varga
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A Bolliger, D Varga
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6-Amino derivatives of stigmastanol and cholestanol
Journal of Medicinal Chemistry, 1971H, Pinhas +5 more
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