Results 81 to 90 of about 3,700 (219)
Dieser Review diskutiert mechanochemische Strategien zur späten Modifizierung bioaktiver Wirkstoffe und bietet zugleich eine wertvolle Übersicht zur Auswahl geeigneter Substrate, um das pharmazeutische Potenzial neuer und bestehender (mechano)chemischer Verfahren zu evaluieren.
Johanna Templ, Lars Borchardt
wiley +1 more source
This review highlights mechanochemical strategies for the late‐stage modification of active pharmaceutical ingredients (APIs), providing a valuable resource for selecting substrates to evaluate the pharmaceutical potential of novel and existing (mechano)chemical protocols.
Johanna Templ, Lars Borchardt
wiley +1 more source
Сerebrotendinous xanthomatosis
Cerebrotendinous xanthomatosis is a rare autosomal recessivedisorder of cholesterol and bile acid metabolism associated withthe sterol 27-hydroxylase gene CYP27A1.
G. E. Rudenskaya, E. Yu. Zakharova
doaj +1 more source
Analysis of phytosterols in foods [PDF]
Phytosterols are bioactive compounds, one of their most studied and outstanding properties being their cholesterol-lowering activity. This explains the growing interest in the phytosterol contents of foods as either intrinsic or added components.
Farré Rovira, Rosaura +2 more
core +1 more source
Autosomal Recessive Cerebellar Ataxias: Translating Genes to Therapies
[Color figure can be viewed at www.annalsofneurology.org] Autosomal recessive cerebellar ataxias are disabling neurodegenerative genetic conditions affecting balance and coordination. Advancements in genomic testing have improved diagnosis, leading to a new focus on the development of targeted precision therapeutics addressing cellular, biochemical ...
Brent L. Fogel +10 more
wiley +1 more source
Characteristics of Lipid Biomarkers (N-alkanes, Fatty Acids, Sterols, N-alkanols and Isoprenoid) in Estuarine Sediments of Muara Angke Jakarta Bay and Cilintang-ujung Kulon [PDF]
Lipid biomarkers as specific organic compounds can be used to evaluate the possible contribution of organic carbon from different sources or to trace the biological origin of molecules.
Nugraha, M. A. (Mohammad) +2 more
core
Detergent design parameters determine experimental successes in membrane protein research. Recent progresses in detergent chemistry are reviewed to promote the top‐down design of non‐ionic detergents for the purification and analysis of intact membrane proteins, including lipid interactions.
Katharina Alker +2 more
wiley +1 more source
The roach Eurycotis floridana was reared on a semisynthetic diet containing minimal cholesterol-4-14C (0.005%) supplemented with cholestanol-7α-3H (0.1%), and various tissues of the insect were separated into ``nuclear,'' ``mitochondrial,'' and ...
N.L. Lasser, R.B. Clayton
doaj +1 more source
Deposition of Cholesterol and Cholestanol in Experimental Rabbit Atherosclerosis.
SummaryContrary to the original findings it is established that cholesterol-C14 and cholesterol-H3 are deposited in tissues of rabbits in exactly the same way. The reason for the discrepancy in deposition of the two substances in earlier experiments was found in the presence of chemically negligible traces of cholestanol-H3 which had then not been ...
E, SCHWENK, Y, OMORI, E, JOACHIM
openaire +2 more sources
We have measured plasma sterol composition in 14 subjects with sitosterolemia and xanthomatosis. In addition to elevated plasma phytosterol (campesterol 16 +/- 7 mg/dl and sitosterol 35 +/- 16 mg/dl) and normal to moderately high cholesterol levels (258 +
G Salen +7 more
doaj +1 more source

