Synthesis of 24-heteroatom-substituted cholestanols
Short syntheses of 24-thia-5 alpha,20 xi-cholestan-3 beta-ol, 24-methyl-24-aza-5 alpha,20 xi-cholestan-3 beta-ol, and 24-nor-5 alpha,20 xi-cholan-3 beta-ol from 3 beta-hydroxy-5 alpha-pregnan-20-one are described. The products and synthetic intermediates
M D Rahman, H M Seidel, R A Pascal, Jr
exaly +7 more sources
Synthesis of conjugated cholesterol and cholestanols.
The glucuronides, sulfates, glucosides and N-acetylglucosaminides of cholesterol and epimeric 5α-cholestan-3-ols have been synthesized. The formation of a β-glucoside linkage was readily achieved by means of the Koenigs-Knorr reaction with the corresponding α-acetohalosugar, employing cadmium carbonate as a catalyst.
JUNICHI GOTO +2 more
openaire +2 more sources
Presenile Cataract: Consider Cholestanol [PDF]
Contains fulltext : 50065.pdf (Publisher’s version ) (Closed access)
Teszas, A. +6 more
openaire +5 more sources
Relation of sterol structure to utilization in pleuropneumonia-like organisms
Six sterols, Δ5-cholesten-3Β-ol (cholesterol), Δ5-cholesten-3α-ol, cholestan-3Β-ol, cholestan-3α-ol, coprostan-3Β-ol, and coprostan-3α-ol, selected to represent variations in the configuration of the A and B rings and of the 3-hydroxyl group, were tested
Paul F. Smith
doaj +1 more source
Crystal structure of cholestanyl caprylate and binary phase behavior with cholesteryl caprylate.
The crystal structure of cholestanyl n-octanoate (caprylate) (C35H62O2) is monoclinic with space group A2 and cell dimensions a = 10.103(7), b = 7.646(7), c = 87.63(7) A, beta = 90.51(6) degrees; Z = 8 [two molecules (A, B) in asymmetric unit], V = 6769 ...
GW Han, BM Craven
doaj +1 more source
Ypsiyunnosides A–E, Five New Cholestanol Glycosides from Ypsilandra yunnanensis [PDF]
Phytochemical investigation on the whole plants of Ypsilandra yunnanensis was carried out for the first time and led to the isolation of five new cholestanol glycosides, ypsiyunnosides A-E (1-5), and one known analogue. Their structures were determined mainly by detailed spectroscopic analysis, including extensive 1D and 2D NMR, MS and UV, as well as ...
Chen, Yu +6 more
openaire +2 more sources
Deposition of Cholesterol and Cholestanol in Experimental Rabbit Atherosclerosis.
SummaryContrary to the original findings it is established that cholesterol-C14 and cholesterol-H3 are deposited in tissues of rabbits in exactly the same way. The reason for the discrepancy in deposition of the two substances in earlier experiments was found in the presence of chemically negligible traces of cholestanol-H3 which had then not been ...
E, SCHWENK, Y, OMORI, E, JOACHIM
openaire +2 more sources
Targeting NR1H/liver X receptor with dendrogenin A differentiates tumor cells to activate a new secretory pathway releasing immunogenic anti-tumor vesicles enriched in LC3-II-associated exosomes. [PDF]
de Medina P +4 more
europepmc +1 more source
Cholestanol accelerates α-synuclein aggregation and spreading by activating asparagine endopeptidase. [PDF]
Yu T +13 more
europepmc +1 more source
6-Polyaminosteroid Squalamine Analogues Display Antibacterial Activity against Resistant Pathogens. [PDF]
Vergoz D +13 more
europepmc +1 more source

