Results 41 to 50 of about 267 (172)

Autosomal Recessive Cerebellar Ataxias: Translating Genes to Therapies

Annals of Neurology, Volume 98, Issue 3, Page 448-470, September 2025.
[Color figure can be viewed at www.annalsofneurology.org] Autosomal recessive cerebellar ataxias are disabling neurodegenerative genetic conditions affecting balance and coordination. Advancements in genomic testing have improved diagnosis, leading to a new focus on the development of targeted precision therapeutics addressing cellular, biochemical ...
Brent L. Fogel, Thomas Klopstock, David R. Lynch, Francesca Maltecca, Mayank Verma, Berge A. Minassian, Frances M. Platt, Débora Farina Gonçalves, Hélène Puccio, Andreas Roos, Matthis Synofzik   +10 more
wiley   +1 more source

Recent Advances in Detergent Chemistry and Handling Support Membrane Protein Analysis Including Lipid Interactions

Chemistry – A European Journal, Volume 31, Issue 49, September 1, 2025.
Detergent design parameters determine experimental successes in membrane protein research. Recent progresses in detergent chemistry are reviewed to promote the top‐down design of non‐ionic detergents for the purification and analysis of intact membrane proteins, including lipid interactions.
Katharina Alker, Jan‐Simon Behnke, Leonhard H. Urner   +2 more
wiley   +1 more source

Hydrocarbon biomarkers for biotic and environmental evolution through the Neoproterozoic-Cambrian transition [PDF]

, 2009
Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Earth, Atmospheric, and Planetary Sciences, 2009.This electronic version was submitted by the student author.
Kelly, Amy E. (Amy Elizabeth), 1980-
core  

Functional analysis of UDP-sugar : sterol glucosyltransferases [PDF]

, 2011
Glycosyltransferases (GTs) are essential for the biosynthesis and diversification of many therapeutically important natural products. Of these, UDP-sugar: sterol glucosyltransferases (UGTs) (2.4.1.173) catalyse the synthesis of therapeutically important ...
Black, Gary, Malik, Vatsala
core  

Methylation of alcohols with diazomethane

, 1958
Alcoholic hydroxyl groups were methylated by diazomethane in the presence of catalytic amounts of fluoboric acid (FBA). Primary aliphatic and unhindered secondary alcohols gave 84–98% yields of methyl ethers, while tertiary and moderately hindered ...
Caserio, Marjorie C., Johnson, Williams S., Neeman, M., Roberts, John D.   +3 more
core   +1 more source

Preparation and determination of configuration of 3-halogeno-3-methyl-5 alpha-cholestane epimers

, 1986
3α- Chloro- 3β- methyl - and 3β- chloro- 3α- methyl - 5α- cholestane were prepared by reaction of hydrochloric acid with the two epimeric 3- hydroxy-3-methyl-5α-cholestanes.
Busson, Roger, Vanderhaeghe, Hubert, Vanrobays, M   +2 more
core   +1 more source

Enzymatic and Molecular Characterization of Anti-Leishmania Molecules That Differently Target Leishmania and Mammalian eIF4A Proteins, LieIF4A and eIF4A_Mus. [PDF]

Molecules, 2022
Abdelkrim YZ, Harigua-Souiai E, Bassoumi-Jamoussi I, Barhoumi M, Banroques J, Essafi-Benkhadir K, Nilges M, Blondel A, Tanner NK, Guizani I.   +9 more
europepmc   +1 more source

FATE OF ERGOSTEROL AND CHOLESTANOL IN PLEUROPNEUMONIA-LIKE ORGANISMS [PDF]

Journal of Bacteriology, 1962
Smith, Paul F. (University of South Dakota, Vermillion). Fate of ergosterol and cholestanol in pleuropneumonia-like organisms. J. Bacteriol. 84: 534–538. 1962.—Cholesterol, an essential growth requirement of certain pleuropneumonia-like organisms, can be replaced by ergosterol or cholestanol.
openaire   +2 more sources

Occurrence of plant and fecal steroid and their evolution during co-composting of sewage sludge and lignocellulosic waste

, 2016
International audienceSteroid composition change during six months of co-composting of sewage sludge and palm waste was studied using Py-GC/MS. The main steroids identified were C27–C29 sterenes and stanols, 5β-cholesta-3-one, cholesta-3,5-diene and 2 ...
Ambles, André, Fels, Loubna El, Geffroy, Claude, Hafidi, Mohamed, Lemée, Laurent, Ouaqoudi, Fatima Zahra El   +5 more
core   +3 more sources

Optimal Brassinosteroid Levels Are Required for Soybean Growth and Mineral Nutrient Homeostasis. [PDF]

Int J Mol Sci, 2021
Cheng L, Li M, Min W, Wang M, Chen R, Wang W.   +5 more
europepmc   +1 more source