Results 31 to 40 of about 267 (172)

Cholesteryl Fatty Acid Esters and Free Cholesterol in Food of Animal Origin

open access: yesEuropean Journal of Lipid Science and Technology, Volume 128, Issue 1, January 2026.
Cholesterol occurs in free (bioavailable) and esterified (transport/storage) forms. Here, we present a method that allows both forms to be determined independently. Finally, the quantities of free and esterified cholesterol were determined in several meat, animal fat, and cheese samples.
Vanessa Hermann‐Ene   +3 more
wiley   +1 more source

Arabidopsis root lipid droplets are hubs for membrane homeostasis under heat stress, and triterpenoid synthesis and storage

open access: yesNew Phytologist, Volume 249, Issue 2, Page 892-916, January 2026.
Summary Plant lipid droplets (LDs) and their associated proteins have numerous subcellular and physiological functions. While considerable progress has been made for LDs in many tissues, the function and composition of LDs in roots remain largely unexplored.
Patricia Scholz   +22 more
wiley   +1 more source

The Influence of Schwann Cell Metabolism and Dysfunction on Axon Maintenance

open access: yesGlia, Volume 73, Issue 12, Page 2338-2352, December 2025.
Main Points Sensory neurons depend on Schwann cells for survival. Schwann cells provide energy for axons dunng rapid firing or after injury. Dysregulated metabolism in Schwann cells can lead to the production of neurotoxic and axon degeneration. ABSTRACT Schwann cells are the glial cells in the peripheral nervous system responsible for the production ...
Rose Follis   +2 more
wiley   +1 more source

FDA Approves First Targeted Treatment for Cerebrotendinous Xanthomatosis: A Perspective on a Landmark in Rare Lipid Storage Disease Therapy

open access: yesHealth Science Reports, Volume 8, Issue 12, December 2025.
ABSTRACT Background and Aims Cerebrotendinous xanthomatosis (CTX) is a rare autosomal recessive disorder caused by mutations in the CYP27A1 gene, leading to deficient sterol 27‐hydroxylase activity. This enzyme is critical for bile acid synthesis, and its dysfunction results in reduced chenodeoxycholic acid (CDCA) levels and subsequent accumulation of ...
Laiba Jalal   +2 more
wiley   +1 more source

Information Theory Analysis of CTX Shows Consistent Clinical Presentation

open access: yesJournal of Inherited Metabolic Disease, Volume 48, Issue 6, November 2025.
ABSTRACT Cerebrotendinous xanthomatosis (CTX) is a rare, metabolic disorder caused by pathogenic variants in CYP27A1. The classic clinical presentation includes infantile‐onset chronic diarrhea, juvenile‐onset bilateral cataracts, with development of tendon xanthomas and progressive neurological dysfunction.
Jennifer Hanson, Penelope E. Bonnen
wiley   +1 more source

Vegan diet and nutritional status in infants, children and adolescents: A position paper based on a systematic search by the ESPGHAN Nutrition Committee

open access: yesJournal of Pediatric Gastroenterology and Nutrition, Volume 81, Issue 5, Page 1318-1345, November 2025.
Abstract Vegan and other plant‐based diets are becoming increasingly popular in the paediatric age group. There is limited evidence in the current medical literature to determine whether a vegan diet is adequate for children, since the currently available society position papers are based on narrative reviews and expert opinion.
Elvira Verduci   +11 more
wiley   +1 more source

Suivi physico-chimique, microbiologique et écotoxicologique du compostage de boues de STEP mélangées à des déchets de palmier : validation de nouveaux indices de maturité [PDF]

open access: yes, 2014
Le traitement de boues de station d'épuration (Boues activées de Marrakech) en mélange avec déchets verts (Palmier dattier) selon deux mélanges dont les proportions : A (1/3 Boues + 2/3 Déchets de palmier) et B (1/2 Boues + 1/2 Déchets de palmier), a été
El Fels, Loubna
core  

Mechanochemische Methoden mit Anwendung in der Late‐Stage Modifizierung Pharmazeutisch Wirksamer Verbindungen

open access: yesAngewandte Chemie, Volume 137, Issue 41, October 6, 2025.
Dieser Review diskutiert mechanochemische Strategien zur späten Modifizierung bioaktiver Wirkstoffe und bietet zugleich eine wertvolle Übersicht zur Auswahl geeigneter Substrate, um das pharmazeutische Potenzial neuer und bestehender (mechano)chemischer Verfahren zu evaluieren.
Johanna Templ, Lars Borchardt
wiley   +1 more source

Mechanochemical Strategies Applied to the Late‐Stage Modifications of Pharmaceutically Active Compounds

open access: yesAngewandte Chemie International Edition, Volume 64, Issue 41, October 6, 2025.
This review highlights mechanochemical strategies for the late‐stage modification of active pharmaceutical ingredients (APIs), providing a valuable resource for selecting substrates to evaluate the pharmaceutical potential of novel and existing (mechano)chemical protocols.
Johanna Templ, Lars Borchardt
wiley   +1 more source

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