Results 101 to 110 of about 214 (123)
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Cholestanol-Induced Gallstones: Radiologic Observations
Radiology, 1967Gallstones can be reliably induced in rabbits by the addition of 3-beta-cholestanol to an otherwise normal diet. This initial observation of Bevans and Mosbach (2) has been confirmed by others (3, 6, 8) and has been found to be a useful experimental model.
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Plasma Esterification of Cholestanol, Normally and in Cerebrotendinous Xanthomatosis
Scandinavian Journal of Clinical and Laboratory Investigation, 1974In vitro esterification of labeled cholestanol was demonstrated in normal plasma as well as in plasma from patients with cerebrotendinous xanthomatosis, the rate of esterification being about 70 per cent of that of cholesterol. In familial lecithin:cholesterol acyltransferase (LCAT) deficiency no esterification either of cholesterol or of cholestanol ...
S, Skrede, K T, Stokke
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Cholestanol Metabolism, Molecular Pathology, and Nutritional Implications
Journal of Medicinal Food, 2003Cholestanol, not cholesterol, is a minor component in the human body and in foods, but an increase in cholestanol concentration in serum induces a pathological condition named cerebrotendinous xanthomatosis (CTX). In our investigation of this disease for more than 25 years, a procedure for quantification of cholestanol by high-performance liquid ...
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Studies on the biosynthesis of cholestanol in cultured cells.
Journal of biochemistry, 1983The presence of cholestanol had never been reported in cultured cells, but in the present study cholestanol was detected both in human and rat skin fibroblasts. The present study has shown that the origin of cholestanol in these fibroblasts was derived from de novo synthesis in the cells rather than from the fetal calf serum used in the growth medium ...
S, Serizawa +3 more
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Australian Journal of Experimental Biology and Medical Science, 1960
A Bolliger, D Varga
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A Bolliger, D Varga
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Gallstone formation in cholestanol-fed mice.
Journal of biochemistry, 1993We examined the effect of cholestanol (5 alpha-dihydrocholesterol) on cholesterol and bile acid metabolism in BALB/c mice. After feeding 1% cholestanol in the diet for 14 months, gallstones composed of 55% cholesterol and 45% cholestanol developed in 20% of the mice and were associated with mucosal inflammation and serosal vessel thickening of the ...
K S, Kim +5 more
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6-Amino derivatives of stigmastanol and cholestanol
Journal of Medicinal Chemistry, 1971H, Pinhas +5 more
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Cholestanol Deposition in Cerebrotendinous Xanthomatosis
Annals of Internal Medicine, 1971openaire +2 more sources