Results 1 to 10 of about 75,877 (184)

Severe cholestasis in neonatal extracorporeal membrane oxygenation [PDF]

The Journal of ExtraCorporeal Technology
Introduction: Cholestasis is a common complication of Extracorporeal Membrane Oxygenation (ECMO) secondary to patient physiology and circuit-induced factors.
Jancaric Michelle, Langworthy Benjamin, Guiang Sixto, Segura Bradley, Wallace Rachel, Larson-Nath Catherine, Satrom Katherine M.   +6 more
doaj   +2 more sources

Outcomes of 38 patients with PFIC3: Impact of genotype and of response to ursodeoxycholic acid therapy

JHEP Reports, 2023
Background & Aims: Progressive familial intrahepatic cholestasis type 3 (PFIC3) is a rare liver disease caused by biallelic variations in ABCB4. Data reporting on the impact of genotype and of response to ursodeoxycholic acid (UDCA) therapy on long ...
Emmanuel Gonzales, Antoine Gardin, Marion Almes, Amaria Darmellah-Remil, Hanh Seguin, Charlotte Mussini, Stéphanie Franchi-Abella, Mathieu Duché, Oanez Ackermann, Alice Thébaut, Dalila Habes, Bogdan Hermeziu, Martine Lapalus, Thomas Falguières, Jean-Philippe Combal, Bernard Benichou, Sonia Valero, Anne Davit-Spraul, Emmanuel Jacquemin   +18 more
doaj   +1 more source

Effect of transient obstructive cholestasis on liver histology: a cross-sectional study

São Paulo Medical Journal, 2021
BACKGROUND: The role of transient obstructive cholestasis on liver histology remains undetermined. OBJECTIVE: To investigate whether transient cholestasis impairs liver histology.
Thalita Mendes Mitsunaga, Laísa Simakawa Jimenez, Pedro França da Costa Soares, Martinho Antonio Gestic, Murillo Pimentel Utrini, Felipe David Mendonça Chaim, Francisco Callejas-Neto, Elinton Adami Chaim, Everton Cazzo   +8 more
doaj   +1 more source

CHRONIC CHOLESTASIS IN INFANCY [PDF]

Romanian Journal of Pediatrics, 2009
This article focuses on the few disorders that produce chronic cholestasis in infants. The author presents: definition and pathophysiology of cholestasis; the consequences of cholestasis; an approach to diagnosis of cholestasis in infancy and childhood;
Daniela Patrichi
doaj   +1 more source

Neonatal cholestasis as the onset symptom of McCune–Albright syndrome: case reports and a literature review

Frontiers in Pediatrics, 2023
AimThis study aimed to summarize and show the characteristics and evolutionary process of neonatal cholestasis caused by McCune–Albright syndrome (MAS), as neonatal cholestasis may be the initial manifestation of MAS before other classic clinical ...
Weiyuan Fang, Yanhui Zhang, Lian Chen, Xinbao Xie   +3 more
doaj   +1 more source

Biomarkers of Cholestasis [PDF]

Biomarkers in Medicine, 2021
Cholestasis is a major pathological manifestation, often resulting in detrimental liver conditions, which occurs in a variety of indications collectively termed cholestatic liver diseases. The frequent asymptomatic character and complexity of cholestasis, together with the lack of a straightforward biomarker, hampers early detection and treatment of ...
Pieters, Alanah, Gijbels, Eva, Cogliati, Bruno, Annaert, Pieter, Devisscher, Lindsey, Vinken, Mathieu   +5 more
openaire   +4 more sources

A meta-analysis of the prevalence of gestational diabetes in patients diagnosed with obstetrical cholestasisAJOG Global Reports at a Glance

AJOG Global Reports, 2021
BACKGROUND: Gestational diabetes and obstetrical cholestasis are common clinical conditions seen in clinical practice. There is evidence suggesting a coexisting relationship that could have a potential clinical implication related to stillbirth outcomes.
Manoj Mohan, MRCOG, Sanjay Swargathmadhom Prabhu, MRCOG, Abdul Kareem Pullattayil, MSIt, Stephen Lindow, FRCOG   +3 more
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Neonatal Cholestasis [PDF]

Seminars in Pediatric Surgery, 2000
In simplest terms, cholestasis is defined as a decrease in bile flow. The clinical manifestations of cholestasis occur because of accumulation of substances normally excreted in the bile; namely bilirubin, bile acids, and cholesterol. Accumulation of bilirubin leads to jaundice and dark urine. Accumulation of bile acids is associated with pruritus, and
F M, Karrer, D D, Bensard
openaire   +4 more sources

Cholestasis: exploring the triangular relationship of gut microbiota-bile acid-cholestasis and the potential probiotic strategies

Gut Microbes, 2023
Cholestasis is a condition characterized by the abnormal production or excretion of bile, and it can be induced by a variety of causes, the factors of which are extremely complex.
Leilei Yu, Yaru Liu, Shunhe Wang, Qingsong Zhang, Jianxin Zhao, Hao Zhang, Arjan Narbad, Fengwei Tian, Qixiao Zhai, Wei Chen   +9 more
doaj   +1 more source

Hypercortisolism in patients with cholestasis is associated with disease severity

BMC Gastroenterology, 2021
Background Cholestasis might lead to an impairment of adrenal function as suggested by in vitro and in vivo data as well as by clinical findings. Bile acid and adrenal steroid metabolism not only share the receptors farnesoid X receptor (FXR) and the G ...
Verena Theiler-Schwetz, Hansjörg Schlager, Barbara Obermayer-Pietsch, Tatjana Stojakovic, Günter Fauler, Peter Fickert, Gernot Zollner   +6 more
doaj   +1 more source