Results 91 to 100 of about 99,236 (370)

Saikosaponin b1 Attenuates Liver Fibrosis by Blocking STAT3/Gli1 Interaction and Inducing Gli1 Degradation

open access: yesExploration, EarlyView.
Saikosaponin b1 attenuates liver fibrosis by competitively disrupting the interaction between signal transducer and activator of transcription 3 (STAT3) and glioma‐associated oncogene‐1 (Gli1) in the activated hepatic stellate cells (HSCs). The blocked interaction of STAT3 and Gli1 promotes the degradation of Gli1, inhibits Gli1 transcriptional ...
Meiyu Shao   +15 more
wiley   +1 more source

CAQ Corner: Immune‐mediated complications

open access: yes, 2022
Liver Transplantation, EarlyView.
Mary Thomson, John R. Lake
wiley   +1 more source

Obstetrical and neonatal complications in hereditary haemorrhagic telangiectasia: A retrospective study

open access: yesBJOG: An International Journal of Obstetrics &Gynaecology, Volume 130, Issue 3, Page 303-311, February 2023., 2023
Abstract Objective To retrospectively describe a large series of pregnancies in women with hereditary haemorrhagic telangiectasia followed in our reference centre, plus neonatal outcomes, to better understand the risks of complications and to improve their prevention.
Laura Delagrange   +5 more
wiley   +1 more source

Liver Transplantation for Alagille's Syndrome [PDF]

open access: yes, 1993
Twenty-three children with Alagille's syndrome and end-stage liver disease underwent liver transplantation with cyclosporine and low-dose steroid immunosuppression. Two to 9 years (mean, 4.4 years) after surgery, 13 (57%) of the children were still alive,
Reyes, J   +5 more
core   +1 more source

Expanding etiology of progressive familial intrahepatic cholestasis

open access: yesWorld Journal of Hepatology, 2019
BACKGROUND Progressive familial intrahepatic cholestasis (PFIC) refers to a disparate group of autosomal recessive disorders that are linked by the inability to appropriately form and excrete bile from hepatocytes, resulting in a hepatocellular form of ...
Sarah A F Henkel   +5 more
semanticscholar   +1 more source

Organ‐on‐Chip: The Future of Nutrition Research in a One Health World

open access: yesFood Frontiers, EarlyView.
Organ‐on‐chips offer a promising tool for evaluating food and feed safety. Organ‐on‐chips also present a scientifically robust and ethical alternative to animal studies. ABSTRACT The One Health approach emphasizes the interconnectedness of human, animal, and environmental health, recognizing that the health of each is interdependent and influenced by ...
Manuela Cassotta   +8 more
wiley   +1 more source

Idiopathic Intrahepatic Cholestasis as an Unusual Presentation of Hodgkin’s Disease

open access: yesCase Reports in Hematology, 2015
Intrahepatic cholestasis in the form of paraneoplastic phenomena is an uncommon presentation of Hodgkin’s lymphoma (HL). Herein we report the diagnosis of mixed type HL-related idiopathic intrahepatic cholestasis in a 73-year-old man presenting with ...
Hande Atalay   +6 more
doaj   +1 more source

Cholestasis: human disease and experimental animal models

open access: yesAnnals of Hepatology, 2003
Cholestasis may result from a failure in bile secretion in hepatocytes or ductular cells, or from a blockade to the free bile flow. Human cholestasis may be induced by many drugs, being antibiotics the more common.
Emilio Alberto Rodríguez-Garay, MD, PhD
doaj  

Bile acid-gut microbiota imbalance in cholestasis and its long-term effect in mice

open access: yesmSystems
Cholestasis is a common morbid state that may occur in different phases; however, a comprehensive evaluation of the long-term effect post-recovery is still lacking.
Xin Yang   +9 more
doaj   +1 more source

Preventive effect of ursodeoxycholic acid on parenteral nutrition-associated liver disease in infants [PDF]

open access: yesSrpski Arhiv za Celokupno Lekarstvo, 2014
Introduction. Parenteral nutrition-associated cholestasis is well recognized phenomenon in the term and preterm infant receiving long-term parenteral nutrition. Objectives. The aim of this study was to evaluate the effect of ursodeoxycholic acid
Simić Dušica   +8 more
doaj   +1 more source

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