Results 91 to 100 of about 99,236 (370)
Saikosaponin b1 attenuates liver fibrosis by competitively disrupting the interaction between signal transducer and activator of transcription 3 (STAT3) and glioma‐associated oncogene‐1 (Gli1) in the activated hepatic stellate cells (HSCs). The blocked interaction of STAT3 and Gli1 promotes the degradation of Gli1, inhibits Gli1 transcriptional ...
Meiyu Shao+15 more
wiley +1 more source
CAQ Corner: Immune‐mediated complications
Liver Transplantation, EarlyView.
Mary Thomson, John R. Lake
wiley +1 more source
Abstract Objective To retrospectively describe a large series of pregnancies in women with hereditary haemorrhagic telangiectasia followed in our reference centre, plus neonatal outcomes, to better understand the risks of complications and to improve their prevention.
Laura Delagrange+5 more
wiley +1 more source
Liver Transplantation for Alagille's Syndrome [PDF]
Twenty-three children with Alagille's syndrome and end-stage liver disease underwent liver transplantation with cyclosporine and low-dose steroid immunosuppression. Two to 9 years (mean, 4.4 years) after surgery, 13 (57%) of the children were still alive,
Reyes, J+5 more
core +1 more source
Expanding etiology of progressive familial intrahepatic cholestasis
BACKGROUND Progressive familial intrahepatic cholestasis (PFIC) refers to a disparate group of autosomal recessive disorders that are linked by the inability to appropriately form and excrete bile from hepatocytes, resulting in a hepatocellular form of ...
Sarah A F Henkel+5 more
semanticscholar +1 more source
Organ‐on‐Chip: The Future of Nutrition Research in a One Health World
Organ‐on‐chips offer a promising tool for evaluating food and feed safety. Organ‐on‐chips also present a scientifically robust and ethical alternative to animal studies. ABSTRACT The One Health approach emphasizes the interconnectedness of human, animal, and environmental health, recognizing that the health of each is interdependent and influenced by ...
Manuela Cassotta+8 more
wiley +1 more source
Idiopathic Intrahepatic Cholestasis as an Unusual Presentation of Hodgkin’s Disease
Intrahepatic cholestasis in the form of paraneoplastic phenomena is an uncommon presentation of Hodgkin’s lymphoma (HL). Herein we report the diagnosis of mixed type HL-related idiopathic intrahepatic cholestasis in a 73-year-old man presenting with ...
Hande Atalay+6 more
doaj +1 more source
Cholestasis: human disease and experimental animal models
Cholestasis may result from a failure in bile secretion in hepatocytes or ductular cells, or from a blockade to the free bile flow. Human cholestasis may be induced by many drugs, being antibiotics the more common.
Emilio Alberto Rodríguez-Garay, MD, PhD
doaj
Bile acid-gut microbiota imbalance in cholestasis and its long-term effect in mice
Cholestasis is a common morbid state that may occur in different phases; however, a comprehensive evaluation of the long-term effect post-recovery is still lacking.
Xin Yang+9 more
doaj +1 more source
Preventive effect of ursodeoxycholic acid on parenteral nutrition-associated liver disease in infants [PDF]
Introduction. Parenteral nutrition-associated cholestasis is well recognized phenomenon in the term and preterm infant receiving long-term parenteral nutrition. Objectives. The aim of this study was to evaluate the effect of ursodeoxycholic acid
Simić Dušica+8 more
doaj +1 more source