Idiopathic Intrahepatic Cholestasis as an Unusual Presentation of Hodgkin’s Disease
Intrahepatic cholestasis in the form of paraneoplastic phenomena is an uncommon presentation of Hodgkin’s lymphoma (HL). Herein we report the diagnosis of mixed type HL-related idiopathic intrahepatic cholestasis in a 73-year-old man presenting with ...
Hande Atalay+6 more
doaj +1 more source
Effective second-line treatment with cetuximab and bevacizumab in a patient with hepatic metastases of colorectal cancer and hyperbilirubinemia [PDF]
Background: Irinotecan-based second-line chemotherapy of metastatic colorectal cancer (CRC) is effective, it might, however, be contraindicated in cases of severe liver dysfunction due to advanced liver metastases.
Heinemann, Volker+4 more
core +1 more source
Regionally acquired intestinal failure data suggest an underestimate in national service requirements [PDF]
Objectives, setting and patients: With complete case referral for prolonged parenteral nutrition (PN) beyond term equivalent, serving a stable population of 1.25 million people, we describe the long-term outcome and survival of patients referred to an ...
Barclay, Andrew+9 more
core +1 more source
Benign Recurrent Intrahepatic Cholestasis: Where Are We Now?
Benign recurrent intrahepatic cholestasis (BRIC) stands as a rare genetic contributor to cholestasis, aligning itself within the spectrum of inherited intrahepatic cholestasis syndromes, such as progressive familial intrahepatic cholestasis (PFIC) and ...
Eleni V. Geladari+5 more
doaj +1 more source
Parenteral Nutrition-Induced Cholestasis in Neonates: Where Does the Problem Lie?
Background. Parenteral nutrition (PN) is an effective method of nourishing the neonate who is unable to receive full enteral feeds. Cholestasis can be a complication of PN and can lead to severe liver damage. Aim.
Kheira Jolin-Dahel+5 more
doaj +1 more source
Revealing of H. pylori markers at patients with acute viral hepatitises
O-antigenes of H. рylori have been revealed аt patients with acute viral hepatitis (AVH) (57,7%), more often at patients with a cholestasis, than without cholestasis (in feces – 48,6% and 35,4%, in CIC – 14,8% and 4,5%, accord., and VacA (43,5%) and a ...
S. N. Zuevskaja+4 more
doaj +1 more source
∆4-3-oxo-5β-reductase deficiency: favorable outcome in 16 patients treated with cholic acid
Background Oral cholic acid therapy is an effective therapy in children with primary bile acid synthesis deficiencies. Most reported patients with this treatment have 3β-hydroxy-Δ5-C27-steroid oxidoreductase deficiency.
Antoine Gardin+21 more
doaj +1 more source
The impact of elevation of total bilirubin level and etiology of the liver disease on serum N-glycosylation patterns in mice and men [PDF]
The GlycoFibroTest and GlycoCirrhoTest are noninvasive alternatives for liver biopsy that can be used as a follow-up tool for fibrosis patients and to diagnose cirrhotic patients, respectively.
BLOMME, BRAM+5 more
core +1 more source
A Gentleman with Anemia and Cholestasis [PDF]
Primary sclerosing cholangitis is a rare cause of cholestasis caused by progressive inflammation and fibrosis of both intrahepatic and extrahepatic bile ducts leading to multifocal ductal strictures. Herein, we report a case of primary sclerosing cholangitis and inflammatory bowel disease. The concomitant diagnosis of these two diseases is not typical.
Ka-Ho Lok+3 more
openaire +4 more sources
Dose-related liver injury of Geniposide associated with the alteration in bile acid synthesis and transportation. [PDF]
Fructus Gardenia (FG), containing the major active constituent Geniposide, is widely used in China for medicinal purposes. Currently, clinical reports of FG toxicity have not been published, however, animal studies have shown FG or Geniposide can cause ...
Feng, Xiaoyi+17 more
core +2 more sources