Results 101 to 110 of about 99,236 (370)

The impact of elevation of total bilirubin level and etiology of the liver disease on serum N-glycosylation patterns in mice and men [PDF]

, 2010
The GlycoFibroTest and GlycoCirrhoTest are noninvasive alternatives for liver biopsy that can be used as a follow-up tool for fibrosis patients and to diagnose cirrhotic patients, respectively.
BLOMME, BRAM, Callewaert, Nico, Colle, Isabelle, Van Steenkiste, Christophe, Van Vlierberghe, Hans, Vanhuysse, Jacques   +5 more
core   +1 more source

Isolated cortisol deficiency: A rare cause of neonatal cholestasis

The Saudi Journal of Gastroenterology, 2012
For decades, congenital panhypopituitarism has been recognized to cause infantile cholestasis. However, the identity of the hormone whose deficiency causes such derangement of the liver is not clear. Here, we report four cases of isolated severe cortisol
Abdulrahman Al-Hussaini, Awatif Almutairi, Alaaddin Mursi, Mohammed Alghofely, Ali Asery   +4 more
doaj   +1 more source

A case report of vanishing bile duct syndrome after exposure to pexidartinib (PLX3397) and paclitaxel. [PDF]

, 2019
Pexidartinib (PLX3397) is a small molecule tyrosine kinase and colony-stimulating factor-1 inhibitor with FDA breakthrough therapy designation for tenosynovial giant-cell tumor, and currently under study in several other tumor types, including breast ...
Chien, A Jo, Esserman, Laura J, Hyland, Colby, Piawah, Sorbarikor, Rugo, Hope S, Umetsu, Sarah E   +5 more
core  

Effects of cytomegalovirus infection on the differential diagnosis between biliary atresia and intrahepatic cholestasis in a Chinese large cohort study

Annals of Hepatology, 2021
Introduction and objectives: Differentiating biliary atresia from other causes of neonatal cholestasis is challenging, particularly when cytomegalovirus (CMV) and biliary atresia occur simultaneously.
Dongying Zhao, Xiaohui Gong, Yahui Li, Xiaoang Sun, Yan Chen, Zhaohui Deng, Yongjun Zhang   +6 more
doaj  

Effects of chronic cirrhosis induced by intraperitoneal thioacetamide injection on the protein content and Michaelis–Menten kinetics of cytochrome P450 enzymes in the rat liver microsomes

Basic &Clinical Pharmacology &Toxicology, Volume 132, Issue 2, Page 197-210, February 2023., 2023
Abstract Chronic intraperitoneal injection of thioacetamide (TAA) in rats has been used as an animal model of human cirrhosis to study the effects of the disease on drug metabolism. However, TAA inhibits P450 enzymes directly and independently of cirrhosis. We investigated the effects of chronic cirrhosis in rats, induced by 10 weeks of intraperitoneal
Devaraj Venkatapura Chandrashekar, Barent N. DuBois, Mamunur Rashid, Reza Mehvar   +3 more
wiley   +1 more source

Presence of cholestasis and its impact on survival in SARS-CoV-2 associated acute respiratory distress syndrome

Scientific Reports
Data on cholestasis and biliary injury in patients with COVID-19 are scarce. The primary aim of this study was to evaluate the prevalence of cholestasis and factors associated with its development and outcome in critically ill patients with COVID-19 ...
Mathias Schneeweiss-Gleixner, Katharina Krenn, Mathias Petter, Patrick Haselwanter, Felix Kraft, Lukas Adam, Georg Semmler, Lukas Hartl, Emina Halilbasic, Nina Buchtele, Christoph Krall, Thomas Staudinger, Christian Zauner, Michael Trauner, Albert Friedrich Stättermayer   +14 more
doaj   +1 more source

Parenteral Nutrition-Induced Cholestasis in Neonates: Where Does the Problem Lie?

Gastroenterology Research and Practice, 2013
Background. Parenteral nutrition (PN) is an effective method of nourishing the neonate who is unable to receive full enteral feeds. Cholestasis can be a complication of PN and can lead to severe liver damage. Aim.
Kheira Jolin-Dahel, Emanuela Ferretti, Carolina Montiveros, Renee Grenon, Nick Barrowman, Carolina Jimenez-Rivera   +5 more
doaj   +1 more source

UK experience of liver transplantation for erythropoietic protoporphyria [PDF]

, 2011
Erythropoietic protoporphyria (EPP) is characterised by excess production of free protoporphyrin from the bone marrow, most commonly due to deficiency of the enzyme ferrochelatase.
A Dobozy, A Fontanellas, A Herbert, AK Seth, AV Anstey, BM McGuire, Briget K. Gunson, D Samuel, DA Spiva, Darius F. Mirza, DJ Todd, DL Avner, DL Avner, EB Rand, ES Dellon, GH Elder, HJ Wijk van, J Neuberger, JH Meulen van der, JH Reichheld, Joanna K. Dowman, KD Do, KO Morton, L Meerman, MI Leonardi, Mike N. Badminton, MO Doss, Philip N. Newsome, QG Eichbaum, RB Freeman Jr, S Wahlin, S Wahlin, SA Holme, SD Whatley, TH Welling   +34 more
core   +3 more sources

Benign Recurrent Intrahepatic Cholestasis: Where Are We Now?

Gastroenterology Insights
Benign recurrent intrahepatic cholestasis (BRIC) stands as a rare genetic contributor to cholestasis, aligning itself within the spectrum of inherited intrahepatic cholestasis syndromes, such as progressive familial intrahepatic cholestasis (PFIC) and ...
Eleni V. Geladari, Natalia G. Vallianou, Evangelia Margellou, Dimitris Kounatidis, Vassilios Sevastianos, Alexandra Alexopoulou   +5 more
doaj   +1 more source

Cholestasis and meconium ileus in infants with cystic fibrosis and their clinical outcomes [PDF]

, 2014
Objective To identify the incidence and outcomes of cholestasis and meconium ileus (MI) in infants with cystic fibrosis (CF). Design Retrospective cohort study. Setting Single-centre study. Patients From January 1986 to December 2011, 401 infants with CF
Cipolli, Marco, Fitzgerald, Dominic A., Gaskin, Kevin J., Leeuwen, Lisette, Magoffin, Annabel K.   +4 more
core   +1 more source