Results 131 to 140 of about 113,305 (364)

Macrophage-derived IL-1β/NF-κB signaling mediates parenteral nutrition-associated cholestasis

Nature Communications, 2018
In infants intolerant of enteral feeding because of intestinal disease, parenteral nutrition may be associated with cholestasis, which can progress to end-stage liver disease.
K. E. El Kasmi, Padade M. Vue, Aimee L Anderson, M. Devereaux, Swati Ghosh, N. Balasubramaniyan, S. Fillon, Carola Dahrenmoeller, A. Allawzi, Crystal Woods, S. McKenna, C. Wright, Linda K. Johnson, A. D’Alessandro, J. Reisz, E. Nozik-Grayck, F. Suchy, R. Sokol   +17 more
semanticscholar   +1 more source

Histamine stimulates the proliferation of small and large cholangiocytes by activation of both IP3/Ca2+ and cAMP-dependent signaling mechanisms [PDF]

, 2012
Although large cholangiocytes exert their functions by activation of cyclic adenosine 3',5'-monophosphate (cAMP), Ca(2+)-dependent signaling regulates the function of small cholangiocytes. Histamine interacts with four receptors, H1-H4HRs.
Fanyin Meng, FRANCHITTO, Antonio, GAUDIO, EUGENIO, Gianfranco D. Alpini, Guido Carpino, Hannah E. Shine, Heather L. Francis, Julie K. Venter, Kimberly K. Baker, MANCINELLI, ROMINA, Mellanie A. White, ONORI, PAOLO, RENZI, ANASTASIA, Sharon Demorrow, Taylor C. Francis, Yoshiyuki Ueno   +15 more
core   +1 more source

Association of maternal biliary disease with hepatopancreatobiliary morbidity in offspring

Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives Maternal biliary disease is common, but the link with offspring hepatopancreatobiliary disease has not been studied. We assessed the association between maternal biliary disease and pediatric hepatopancreatobiliary morbidity. Methods We conducted a retrospective cohort study of 1,271,864 children born between 2006 and 2022 in Quebec,
Nathalie Auger, Angela Magri, Sarit Kang‐Auger, Gabrielle Jutras, Jessica Healy‐Profitós, Marianne Bilodeau‐Bertrand, Gabriel Côté‐Corriveau   +6 more
wiley   +1 more source

Assessment of aspartate aminotransferase to Platelet Ratio Index and Fibrosis-4 Index score on women with intrahepatic cholestasis of pregnancyAJOG Global Reports at a Glance

AJOG Global Reports
BACKGROUND: Intrahepatic cholestasis of pregnancy is a pregnancy-related liver condition that is characterized by elevated liver function tests and/or bile acids in the presence of pruritis.
Maria Cemortan, PhD, Corina Iliadi-Tulbure, PhD, Irina Sagaidac, PhD, Olga Cernetchi, PhD   +3 more
doaj   +1 more source

Defects in myosin VB are associated with a spectrum of previously undiagnosed low γ‐glutamyltransferase cholestasis

Hepatology, 2017
Hereditary cholestasis in childhood and infancy with normal serum gamma‐glutamyltransferase (GGT) activity is linked to several genes. Many patients, however, remain genetically undiagnosed.
Y. Qiu, J. Gong, Jiayan Feng, Renxue Wang, Jun Han, Teng Liu, Yi Lu, Li-Ting Li, Meihong Zhang, Jonathan A. Sheps, Neng-Li Wang, Yani Yan, Jia-Qi Li, Lian Chen, C. Borchers, B. Sipos, A. Knisely, V. Ling, Qing-He Xing, Jian-She Wang   +19 more
semanticscholar   +1 more source

Neonatologie/Pädiatrie – Leitlinie Parenterale Ernährung, Kapitel 13 [PDF]

, 2009
There are special challenges in implementing parenteral nutrition (PN) in paediatric patients, which arises from the wide range of patients, ranging from extremely premature infants up to teenagers weighing up to and over 100 kg, and their varying ...
Bauer, Karl, Böhles, Hansjosef, Fusch, Christoph, Jochum, Frank, Koletzko, Berthold, Krawinkel, Michael, Krohn, Kathrin, Mühlebach, Stefan   +7 more
core  

Odevixibat after liver transplant in patients with progressive familial intrahepatic cholestasis type 1: A case series

Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives Patients with progressive familial intrahepatic cholestasis type 1 (PFIC1) who have undergone liver transplantation (LT) may have unmet needs and impacts on daily life due to post‐LT complications, including diarrhea and hepatic steatosis.
Georg‐Friedrich Vogel, Simone Kathemann, Andrea Pietrobattista, Giuseppe Maggiore, Denise Aldrian, Marco Sciveres, Henkjan J. Verkade, Etienne Sokal, Giulia Jannone, Magdalena Salcedo, Peter Rauschkolb, Christof Maucksch, Velichka Valcheva, Elke Lainka   +13 more
wiley   +1 more source

Identification of a serum biomarker panel for the differential diagnosis of cholangiocarcinoma and primary sclerosing cholagnitis [PDF]

, 2018
The non-invasive differentiation of malignant and benign biliary disease is a clinical challenge. Carbohydrate antigen 19-9 (CA19-9), leucine-rich α2-glycoprotein (LRG1), interleukin 6 (IL6), pyruvate kinase M2 (PKM2), cytokeratin 19 fragment (CYFRA21.1)
Blyuss, O, Cuenco, J, Dawnay, A, Kazarian, A, Manns, MP, Menon, U, Pereira, SP, Timms, JF, Wehnert, N, Whitwell, HJ   +9 more
core   +2 more sources

Case Report: Intrahepatic cholestasis: a diagnostic dilemma [version 2; peer review: 1 approved, 3 approved with reservations]

Wellcome Open Research
Cholestasis is an impairment of bile formation or bile flow. The mechanisms of cholestasis can be broadly classified into intrahepatic and extrahepatic.
Janak Koirala, Bimal Pandey, Sudeep Adhikari, Ram Chandra Panthi, Buddha Basnyat, Roshan Shrestha, Udit Acharya   +6 more
doaj   +1 more source

The non-HDL-C to APOB ratio as a predictor of inaccurate LDL-C measurement in patients with chronic intrahepatic cholestasis and jaundice: a retrospective study [PDF]

PeerJ
Background Cholestasis is characterized by the accumulation of bile in the liver or biliary system due to obstruction or impaired flow, necessitating lipid profiling to assess lipid metabolism abnormalities.
Yongjiang Cheng, Jingyan Ye, Junyuan Huang, Yang Wang   +3 more
doaj   +2 more sources