Results 141 to 150 of about 107,736 (386)
Progressive familial intrahepatic cholestasis (PFIC) with normal circulating gamma‐glutamyl transpeptidase levels can result from mutations in the ATP8B1 gene (encoding familial intrahepatic cholestasis 1 [FIC1] deficiency) or the ABCB11 gene (bile salt ...
L. Bull+23 more
semanticscholar +1 more source
Abstract Objectives Despite advances in the management of ambulatory paediatric ulcerative colitis (UC), challenges remain as many patients are refractory to therapy and some require colectomy. The aim of these guidelines is to provide an update on optimal care for UC through detailed recommendations and practice points. Methods These guidelines are an
Eytan Wine+24 more
wiley +1 more source
Accumulation of bile salts (BSs) during cholestasis leads to hepatic and biliary injury, driving inflammatory and fibrotic processes. The Na+‐Taurocholate Cotransporting Polypeptide (NTCP) is the major hepatic uptake transporter of BSs, and can be ...
D. Slijepcevic+7 more
semanticscholar +1 more source
Rectal budesonide: A potential game changer after Kasai hepatoportoenterostomy
Abstract Objectives Intravenous or oral steroid administration in patients with biliary atresia (BA) after Kasai hepatoportoenterostomy (HPE) is commonly practiced, however, the benefits remain controversial. Some studies suggest no positive effects while risking steroid associated side effects.
Stefanie Langreen+8 more
wiley +1 more source
Stauffer’s Syndrome in Patient with Metastatic Prostate Cancer
Cholestasis is a symptom that can be present in many conditions, such as bile duct obstruction by malignant mases, obstruction by gallstone, acute and chronic viral hepatitis, and autoimmune disorders, such as primary biliary and sclerosing cholangitis ...
Andris Romašovs+3 more
doaj +1 more source
453 CHOLESTASIS IN THE CEREBRO-HEPATO-RENAL (CHR) SYNDROME: BILE ACID AND MITOCHONDRIAL ABNORMALITIES [PDF]
Richard K. Mathis+3 more
openalex +1 more source
Abstract Objectives Paediatric acute liver failure (PALF) is a rare but life‐threatening condition, yet comprehensive epidemiological data in Germany are lacking. Our study aimed to systematically analyse incidence, aetiology, and outcome of PALF in Germany.
Dominic Lenz+40 more
wiley +1 more source
Objective. Cystatin C is a very potent inhibitor of cysteine proteinases and, it has been clinically applied as a sensitive marker in monitoring of renal and liver functions.
Mehmet Buyukberber, Dr.+7 more
doaj
Abstract Severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2) has known liver tropism. Multiple reports and studies demonstrated liver injury early in the pandemic. This retrospective cross‐sectional comparison evaluates predictors of transaminase elevation during acute SARS‐CoV2 infection, with particular interest in evaluating whether ...
Antonia F. Ovale+6 more
wiley +1 more source