Results 141 to 150 of about 113,305 (364)
JPGN Reports, EarlyView.ABSTRACT Selective androgenic receptor modulators (SARMs) have similar properties to anabolic steroids but bind to androgen receptors in a tissue‐specific manner. Studies have investigated the benefits of SARMs in promoting bone and muscle growth while limiting the adverse effects of androgenic stimulation of other organs.
David J. Katibian +3 more
wiley +1 more source
Hereditary hypofibrinogenemia: A rare cause of chronic liver disease
JPGN Reports, EarlyView.Abstract Hypofibrinogenemia is characterized by low levels of fibrinogen with patients commonly presenting asymptomatically. This report discusses a case of hereditary hypofibrinogenemia manifesting as chronic liver disease in a 2‐year‐old male who was evaluated for elevated liver enzymes and skin/soft tissue bleeding.
Hannah Caringal +4 more
wiley +1 more source
Canine liver transplantation under nva cyclosporine versus cyclosporine [PDF]
, 1986 The immunosuppressive qualities and other features of a new cyclosporine (CsA) analogue, Nva 2-cyclosporine (Nva 2-CsA) were examined using canine orthotopic liver allografts.
DeWolf, A +6 more
core +1 more source
JPGN Reports, EarlyView.ABSTRACT Sickle cell anemia (SCA) is a genetic disorder that presents with a variety of systemic complications, including gastrointestinal (GI) manifestations. These GI symptoms can overlap with those of digestive autoimmune diseases (DAD) such as inflammatory bowel disease (IBD) and autoimmune hepatitis (AIH), complicating the diagnosis and management.
Saray Mesonero Cavia +3 more
wiley +1 more source
European Journal of Inflammation, 2008 Obstetric cholestasis is an intrahepatic multifactorial disease, unique to pregnancy which presents with intense pruritis and abnormal liver function tests (LFTs). It commonly presents in the third trimester and becomes more severe with advanced gestation.
T Tantanasis, Angelos Daniilidis
openaire +3 more sources
Dangerous dietary supplements: Garcinia cambogia-associated hepatic failure requiring transplantation. [PDF]
, 2016 Commercial dietary supplements are marketed as a panacea for the morbidly obese seeking sustainable weight-loss. Unfortunately, many claims cited by supplements are unsupported and inadequately regulated.
Bodzin, Adam S +4 more
core +1 more source
JPGN Reports, EarlyView.Abstract Alagille syndrome (ALGS) is a rare, cholestatic, multisystemic disorder characterized by bile duct paucity. Cholestatic pruritus is a common, and often severe, symptom of ALGS and is the leading cause of liver transplantation. The treatment of cholestatic pruritus is challenging and involves medical and surgical options, such as surgical ...
Chiamaka Nwachukwu +6 more
wiley +1 more source
Recessive Mutations in KIF12 Cause High Gamma‐Glutamyltransferase Cholestasis
Hepatology Communications, 2019 Undiagnosed liver disease remains an unmet medical need in pediatric hepatology, including children with high gamma‐glutamyltransferase (GGT) cholestasis. Here, we report whole‐exome sequencing of germline DNA from 2 unrelated children, both offspring of
Aysel Ünlüsoy Aksu +7 more
semanticscholar +1 more source
JPGN Reports, EarlyView.Abstract Dedicator of cytokinesis 8 (DOCK8) deficiency is a rare autosomal recessive primary immunodeficiency. Patients with DOCK8 deficiency typically present at early age with allergic manifestations, cutaneous and respiratory infections, raised immunoglobulin E, and they have an increased risk of developing malignancies.
Natalia Nedelkopoulou +4 more
wiley +1 more source
A child with debilitating pruritus
Clinics and Practice, 2016 We describe a case of two-year-old boy presenting with debilitating pruritus, patchy alopecia and jaundice since the age of 6 months. On evaluation he had intrahepatic cholestasis with persistently raised serum alkaline phosphatase, normal Gamma glutamyl
Nikhil Sonthalia +7 more
doaj +1 more source