Results 11 to 20 of about 107,736 (386)
Perinatal outcomes of intrahepatic cholestasis during pregnancy: An 8-year case-control study.
PLoS ONE, 2020 INTRODUCTION:Previous studies of fetal effects have suggested that intrahepatic cholestasis of pregnancy is associated with a higher rate of adverse neonatal outcomes including preterm birth, neonatal respiratory distress syndrome, meconium-stained ...
Chloé Arthuis +6 more
doaj +2 more sources
New Insights in Genetic Cholestasis: From Molecular Mechanisms to Clinical Implications
Canadian Journal of Gastroenterology and Hepatology, 2018 Cholestasis is characterised by impaired bile secretion and accumulation of bile salts in the organism. Hereditary cholestasis is a heterogeneous group of rare autosomal recessive liver disorders, which are characterised by intrahepatic cholestasis ...
Eva Sticova +2 more
doaj +2 more sources
Biomarkers of Cholestasis [PDF]
Biomarkers in Medicine, 2021 Cholestasis is a major pathological manifestation, often resulting in detrimental liver conditions, which occurs in a variety of indications collectively termed cholestatic liver diseases. The frequent asymptomatic character and complexity of cholestasis, together with the lack of a straightforward biomarker, hampers early detection and treatment of ...
Alanah Pieters +5 more
openaire +3 more sources
Nature Communications, 2023 Intrahepatic cholestasis of pregnancy (ICP) is a female pregnancy-specific disorder that is characterized by increased serum bile acid and adverse fetal outcomes.
Bo Tang +15 more
semanticscholar +1 more source
Hepatology, 2022 Cholestasis is associated with disease severity and worse outcome in COVID‐19. Cases of secondary sclerosing cholangitis (SSC) after severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) infection have been described.
L. Hartl +20 more
semanticscholar +1 more source
Hepatology, 2021 Cholestasis is characterized by increased total bile acid (TBA) levels, which are regulated by farnesoid X receptor (FXR)/FGF15. Patients with primary sclerosing cholangitis (PSC) typically present with inflammatory bowel disease (IBD). Mast cells (MCs) (
Vik Meadows +13 more
semanticscholar +1 more source
Newer variants of progressive familial intrahepatic cholestasis
World Journal of Hepatology, 2021 Progressive familial intrahepatic cholestasis (PFIC) is a heterogeneous group of disorders characterized by defects in bile secretion and presentation with intrahepatic cholestasis in infancy or childhood. The most common types include PFIC 1 (deficiency
Vignesh Vinayagamoorthy +2 more
semanticscholar +1 more source
The Pathological Mechanisms of Estrogen-Induced Cholestasis: Current Perspectives
Frontiers in Pharmacology, 2021 Estrogens are steroid hormones with a wide range of biological activities. The excess of estrogens can lead to decreased bile flow, toxic bile acid (BA) accumulation, subsequently causing intrahepatic cholestasis.
Y. Zu +3 more
semanticscholar +1 more source
Progressive familial intrahepatic cholestasis
Definitions, 2020 Neonatal cholestasis is one of the commonest presentations in the field of pediatric hepatol‐ ogy and gastroenterology and constitutes the major indication for liver transplantation be‐ low two years of age. Unfortunately, in spite of being common, fewer
R. Khanna, V. Gautam
semanticscholar +1 more source