Results 191 to 200 of about 16,016 (250)

Relative Exchangeable and Exchangeable Copper: Emerging New Biomarkers for Diagnosis and Therapy Monitoring in Wilson's Disease

open access: yesLiver International, Volume 46, Issue 6, June 2026.
ABSTRACT Background and Aims Wilson's disease (WD) is a genetic disorder of copper metabolism in which early diagnosis remains challenging, particularly in acute liver failure (ALF). Relative exchangeable copper (REC) and exchangeable copper (CuEXC) are emerging biomarkers for diagnosis and monitoring, but data from larger cohorts are limited.
Sebastian Köhrer   +10 more
wiley   +1 more source

Primary Sclerosing Cholangitis Recurrence After Liver Transplantation: A Systematic Review and Updated Meta‐Analysis

open access: yesLiver International, Volume 46, Issue 6, June 2026.
ABSTRACT Background and Aims Primary sclerosing cholangitis (PSC) is an immune‐mediated cholestatic liver disease. Liver transplantation (LT) remains the only definitive treatment for patients with advanced disease. However, recurrence of PSC (rPSC) after LT is still a significant clinical challenge.
Isabelle Castro Vitor   +10 more
wiley   +1 more source

Enhancing Preclinical Rigor: Evaluating Robustness and Numerical Stability in a Chronic Pancreatitis Mouse Model

open access: yesAnnals of the New York Academy of Sciences, Volume 1560, Issue 1, June 2026.
In a modified cerulein‐induced chronic pancreatitis (CP) mouse model, key hallmarks of CP were robustly induced in male and female C57BL/6J (BL6) and BALB/c mice, whereas cytokine responses varied partly according to strain and sex. The RORγt inhibitor GSK805 reduced Il23r expression in the BL6 strain, significantly decreased collagen I deposition and ...
Annika Thämlitz   +5 more
wiley   +1 more source

Molecular insights into experimental models and therapeutics for cholestasis

open access: gold
Wenwen Zhang   +7 more
openalex   +1 more source

Chronic Cholestatic Liver Disease Induced by Larval Ascariasis: Novel Insights Into Immune‐Mediated Pathogenesis and Hepatic Fibrosis in Mice

open access: yesThe FASEB Journal, Volume 40, Issue 10, 31 May 2026.
Liver alterations induced by single infection (SI) or reinfection (RE) with 250 or 2500 Ascaris suum eggs in mice. Histological analysis shows inflammatory cell infiltration (eosinophils, lymphocytes, macrophages, and neutrophils), fibrotic areas, and bile duct proliferation in infected animals compared with uninfected controls.
Jorge Lucas Nascimento Souza   +16 more
wiley   +1 more source

[659] EFFECTS OF UDCA ON THE FOETUS-MATERNAL CIRCULATION OF BILIRUBIN IN CHOLESTASIS OF PREGNANCY

open access: bronze, 2007
F. Azzaroli   +13 more
openalex   +1 more source

Intrahepatic Cholestasis

open access: yesJournal of Pediatric Gastroenterology and Nutrition, 2002
openaire   +3 more sources

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