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Histopathological diagnosis of intra- and extrahepatic neonatal cholestasis
The histopathology of the liver is fundamental for the differential diagnosis between intra- and extrahepatic causes of neonatal cholestasis. However, histopathological findings may overlap and there is disagreement among authors concerning those which ...
J.L. Santos+3 more
doaj +1 more source
BACKGROUND: Gestational diabetes and obstetrical cholestasis are common clinical conditions seen in clinical practice. There is evidence suggesting a coexisting relationship that could have a potential clinical implication related to stillbirth outcomes.
Manoj Mohan, MRCOG+3 more
doaj
INTRODUCTION: Cholestasis, otherwise known as bile stasis, occurs when the flow of bile is blocked. There are currently two types of cholestasis: extrahepatic and intrahepatic.
Krzysztof Suszyński+4 more
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Pathologic analysis of liver transplantation for primary biliary cirrhosis [PDF]
A retrospective histopathologic review of all pathologic specimens from 394 adult liver transplant patients was undertaken with clinical correlation to determine if primary biliary cirrhosis has affected the posttrans‐plant course compared to all other ...
Ballardini+25 more
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Identification of PKD1L1 Gene Variants in Children with the Biliary Atresia Splenic Malformation Syndrome [PDF]
Biliary atresia (BA) is the most common cause of end‐stage liver disease in children and the primary indication for pediatric liver transplantation, yet underlying etiologies remain unknown.
Alonso, Estella M+33 more
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Recent advances on the mechanisms regulating cholangiocyte proliferation and the significance of the neuroendocrine regulation of cholangiocyte pathophysiology [PDF]
Cholangiocytes are epithelial cells lining the biliary epithelium. Cholangiocytes play several key roles in the modification of ductal bile and are also the target cells in chronic cholestatic liver diseases (i.e., cholangiopathies) such as PSC, PBC ...
Alvaro, Domenico+6 more
core +1 more source
Recreational exposure during algal bloom in carrasco beach, uruguay: A liver failure case report [PDF]
In January 2015, a 20-month-old child and her family took part in recreational activities at Carrasco and Malvín beaches (Montevideo, Uruguay). An intense harmful algae bloom (HAB) was developing along the coast at that time.
Andrinolo, Dario+8 more
core +3 more sources
Deficiency of Capicua disrupts bile acid homeostasis [PDF]
Capicua (CIC) has been implicated in pathogenesis of spinocerebellar ataxia type 1 and cancer in mammals; however, the in vivo physiological functions of CIC remain largely unknown.
Choi, N+12 more
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Background: Biliary atresia (extrahepatic cholestasis) and neonatal hepatitis (intrahepatic cholestasis) are two main causes of cholestasis. It is important to distinguish the type of cholestasis for determine management.
Bagus Setyoboedi+3 more
doaj +1 more source
Alpha-1 antitrypsin deficiency [PDF]
α-1 antitrypsin is synthesised in the liver and protects lung alveolar tissues from destruction by neutrophil elastase. α-1 antitrypsin deficiency is a common autosomal recessive condition (1:1600 to 1:1800) in which liver disease results from retention ...
Primhak, R.A., Tanner, M.S.
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