Results 61 to 70 of about 113,305 (364)
Objectives: To evaluate the principal risk factors associated with development of intrahepatic cholestasis of pregnancy (ICP) in patients presenting to a tertiary care hospital. Study Design: Case control study.
Rabiah Anwar +5 more
doaj
Histopathological diagnosis of intra- and extrahepatic neonatal cholestasis
The histopathology of the liver is fundamental for the differential diagnosis between intra- and extrahepatic causes of neonatal cholestasis. However, histopathological findings may overlap and there is disagreement among authors concerning those which ...
J.L. Santos +3 more
doaj +1 more source
Alpha-1 antitrypsin deficiency [PDF]
α-1 antitrypsin is synthesised in the liver and protects lung alveolar tissues from destruction by neutrophil elastase. α-1 antitrypsin deficiency is a common autosomal recessive condition (1:1600 to 1:1800) in which liver disease results from retention ...
Primhak, R.A., Tanner, M.S.
core +2 more sources
Liver Transplantation for Alagille's Syndrome [PDF]
Twenty-three children with Alagille's syndrome and end-stage liver disease underwent liver transplantation with cyclosporine and low-dose steroid immunosuppression. Two to 9 years (mean, 4.4 years) after surgery, 13 (57%) of the children were still alive,
Reyes, J +5 more
core +1 more source
THREE CASES WITH BURKITT LYMPHOMA PRESENTING WITH CHOLESTASIS
Case report: Cholestasis secondary to neoplasm is rare in children. It is also rare in Burkitt lymphoma and may be cause to treatment delay. We report 3 cases diagnosed with Burkitt lymphoma with cholestasis.
Fatma Tuba YILDIRIM +6 more
doaj +1 more source
INTRODUCTION: Cholestasis, otherwise known as bile stasis, occurs when the flow of bile is blocked. There are currently two types of cholestasis: extrahepatic and intrahepatic.
Krzysztof Suszyński +4 more
doaj +1 more source
∆4-3-oxo-5β-reductase deficiency: favorable outcome in 16 patients treated with cholic acid
Background Oral cholic acid therapy is an effective therapy in children with primary bile acid synthesis deficiencies. Most reported patients with this treatment have 3β-hydroxy-Δ5-C27-steroid oxidoreductase deficiency.
Antoine Gardin +21 more
doaj +1 more source
Baboon-to-human liver transplantation [PDF]
Our ability to control both the cellular and humoral components of xenograft rejection in laboratory experiments, together with an organ shortage that has placed limits on clinical transplantation services, prompted us to undertake a liver ...
A Tzakis +43 more
core +1 more source
Comparison of human hepatoma HepaRG cells with human and rat hepatocytes in uptake transport assays in order to predict drug induced hepatotoxicity [PDF]
Human hepatocytes are the gold standard for toxicological studies but they have several drawbacks, like scarce availability, high inter-individual variability, a short lifetime, which limits their applicability.
Baranyai, Zsolt +4 more
core +2 more sources
Background: Biliary atresia (extrahepatic cholestasis) and neonatal hepatitis (intrahepatic cholestasis) are two main causes of cholestasis. It is important to distinguish the type of cholestasis for determine management.
Bagus Setyoboedi +3 more
doaj +1 more source

