Results 61 to 70 of about 48,129 (283)

Pathophysiology of sepsis‐induced cholestasis: A review

JGH Open, 2022
Sepsis is a critical condition resulting from the excessive activation of the inflammatory/immune system in response to an infection, with high mortality if treatment is not administered promptly. One of the many possible complications of sepsis is liver
Maria Iuliana Ghenu, Dorin Dragoş, Maria Mirabela Manea, Dorin Ionescu, Lucian Negreanu   +4 more
doaj   +1 more source

Idiopathic Intrahepatic Cholestasis as an Unusual Presentation of Hodgkin’s Disease

Case Reports in Hematology, 2015
Intrahepatic cholestasis in the form of paraneoplastic phenomena is an uncommon presentation of Hodgkin’s lymphoma (HL). Herein we report the diagnosis of mixed type HL-related idiopathic intrahepatic cholestasis in a 73-year-old man presenting with ...
Hande Atalay, Banu Boyuk, Muhammet Ates, Aslan Celebi, Ismail Ekizoglu, Arzu A. Didik, Aysenur A. Igdem   +6 more
doaj   +1 more source

Effects of chronic cirrhosis induced by intraperitoneal thioacetamide injection on the protein content and Michaelis–Menten kinetics of cytochrome P450 enzymes in the rat liver microsomes

Basic &Clinical Pharmacology &Toxicology, Volume 132, Issue 2, Page 197-210, February 2023., 2023
Abstract Chronic intraperitoneal injection of thioacetamide (TAA) in rats has been used as an animal model of human cirrhosis to study the effects of the disease on drug metabolism. However, TAA inhibits P450 enzymes directly and independently of cirrhosis. We investigated the effects of chronic cirrhosis in rats, induced by 10 weeks of intraperitoneal
Devaraj Venkatapura Chandrashekar, Barent N. DuBois, Mamunur Rashid, Reza Mehvar   +3 more
wiley   +1 more source

Presence of cholestasis and its impact on survival in SARS-CoV-2 associated acute respiratory distress syndrome

Scientific Reports
Data on cholestasis and biliary injury in patients with COVID-19 are scarce. The primary aim of this study was to evaluate the prevalence of cholestasis and factors associated with its development and outcome in critically ill patients with COVID-19 ...
Mathias Schneeweiss-Gleixner, Katharina Krenn, Mathias Petter, Patrick Haselwanter, Felix Kraft, Lukas Adam, Georg Semmler, Lukas Hartl, Emina Halilbasic, Nina Buchtele, Christoph Krall, Thomas Staudinger, Christian Zauner, Michael Trauner, Albert Friedrich Stättermayer   +14 more
doaj   +1 more source

Parenteral Nutrition-Induced Cholestasis in Neonates: Where Does the Problem Lie?

Gastroenterology Research and Practice, 2013
Background. Parenteral nutrition (PN) is an effective method of nourishing the neonate who is unable to receive full enteral feeds. Cholestasis can be a complication of PN and can lead to severe liver damage. Aim.
Kheira Jolin-Dahel, Emanuela Ferretti, Carolina Montiveros, Renee Grenon, Nick Barrowman, Carolina Jimenez-Rivera   +5 more
doaj   +1 more source

Revealing of H. pylori markers at patients with acute viral hepatitises

Журнал инфектологии, 2014
O-antigenes of H. рylori have been revealed аt patients with acute viral hepatitis (AVH) (57,7%), more often at patients with a cholestasis, than without cholestasis (in feces – 48,6% and 35,4%, in CIC – 14,8% and 4,5%, accord., and VacA (43,5%) and a ...
S. N. Zuevskaja, O. F. Belaja, O. A. Paevskaja, Ju. A. Belaja, S. G. Pak   +4 more
doaj   +1 more source

Etiologies of neonatal cholestasis at a tertiary hospital in Bangladesh

Paediatrica Indonesiana, 2020
Background Neonatal cholestasis is an important etiology of chronic liver disease in young children. It has a varied etiology. There is considerable delay in presentation and diagnosis of neonatal cholestasis in Bangladesh.
Md. Benzamin, Mukesh Khadga, Fahmida Begum, Md. Rukunuzzaman, Md. Wahiduzzaman Mazumder, Khan Nahid Lamia, Md. Saidul Islam, AZM Raihanur Rahman, ASM Bazlul Karim   +8 more
doaj   +1 more source

Isolated cortisol deficiency: A rare cause of neonatal cholestasis

The Saudi Journal of Gastroenterology, 2012
For decades, congenital panhypopituitarism has been recognized to cause infantile cholestasis. However, the identity of the hormone whose deficiency causes such derangement of the liver is not clear. Here, we report four cases of isolated severe cortisol
Abdulrahman Al-Hussaini, Awatif Almutairi, Alaaddin Mursi, Mohammed Alghofely, Ali Asery   +4 more
doaj   +1 more source

∆4-3-oxo-5β-reductase deficiency: favorable outcome in 16 patients treated with cholic acid

Orphanet Journal of Rare Diseases, 2023
Background Oral cholic acid therapy is an effective therapy in children with primary bile acid synthesis deficiencies. Most reported patients with this treatment have 3β-hydroxy-Δ5-C27-steroid oxidoreductase deficiency.
Antoine Gardin, Mathias Ruiz, Jan Beime, Mara Cananzi, Margarete Rathert, Barbara Rohmer, Enke Grabhorn, Marion Almes, Veena Logarajah, Luis Peña-Quintana, Thomas Casswall, Amaria Darmellah-Remil, Ana Reyes-Domínguez, Emna Barkaoui, Loreto Hierro, Carolina Baquero-Montoya, Ulrich Baumann, Björn Fischler, Emmanuel Gonzales, Anne Davit-Spraul, Sophie Laplanche, Emmanuel Jacquemin   +21 more
doaj   +1 more source

The Immunogenetics of Autoimmune Cholestasis

Clinics in Liver Disease, 2016
The immune-mediated hepatobiliary diseases, primary biliary cirrhosis and primary sclerosing cholangitis are relatively rare, albeit and account for a significant amount of liver transplant activity and liver-related mortality globally. Precise disease mechanisms are yet to be described although a contributory role of genetic predisposition is firmly ...
Palak J. Trivedi, Gideon M. Hirschfield
openaire   +3 more sources