Results 81 to 90 of about 99,236 (370)
Mutations in the nuclear bile acid receptor FXR cause progressive familial intrahepatic cholestasis
Neonatal cholestasis is a potentially life-threatening condition requiring prompt diagnosis. Mutations in several different genes can cause progressive familial intrahepatic cholestasis, but known genes cannot account for all familial cases.
N. Gomez-Ospina+28 more
semanticscholar +1 more source
Sepsis as a cause of intrahepatic cholestasis [PDF]
Introduction. The causes of intrahepatic cholestasis include cholestatic viral hepatitis, primary biliary cirrhosis, benign recurrent cholestasis, primary sclerosing cholangitis and sepsis.
Rudić Jelena+5 more
doaj +1 more source
Regionally acquired intestinal failure data suggest an underestimate in national service requirements [PDF]
Objectives, setting and patients: With complete case referral for prolonged parenteral nutrition (PN) beyond term equivalent, serving a stable population of 1.25 million people, we describe the long-term outcome and survival of patients referred to an ...
Barclay, Andrew+9 more
core +1 more source
Cholestatic jaundice is a common presenting feature of neonatal hepatobiliary and metabolic dysfunction. Any infant who remains jaundiced beyond age 2 to 3 weeks should have the serum bilirubin level fractionated into a conjugated (direct) and unconjugated (indirect) portion. Conjugated hyperbilirubinemia is never physiologic or normal.
Amy G, Feldman, Ronald J, Sokol
openaire +2 more sources
Cholestasis Due to USP53 Deficiency
Objectives: Although a number of genetic forms of cholestasis have been identified, the genetic etiology of disease remains unidentified in a subset of cholestasis patients.
L. Bull+9 more
semanticscholar +1 more source
Markers for internal neoplasia in the horse
The measurement of tumour markers in horses should be performed only in risk groups or in patients with suspicious clinical/laboratory findings (paraneoplastic syndromes). The results should be interpreted with caution as many factors (e.g., young age, pregnancy and inflammation) affect their concentration or activity.
Karolina Drozdzewska, Heidrun Gehlen
wiley +1 more source
A frequent variant in the human bile salt export pump gene ABCB11 is associated with hepatitis C virus infection, but not liver stiffness in a German population [PDF]
Background: The human ATP-binding cassette, subfamily B, member 11 (ABCB11) gene encodes the bile salt export pump, which is exclusively expressed at the canalicular membrane of hepatocytes.
Grünhage, Frank+6 more
core +1 more source
Abstract Aims Although predominant in routine practice, non‐ischaemic cardiogenic shock (NICS) remains underrepresented in past studies, mainly focused on ischaemic cardiogenic shock (CS). This study aims to describe the current NICS picture and define its independent correlates of short‐ and long‐term outcomes.
Miloud Cherbi+20 more
wiley +1 more source
CAQ Corner: Basic concepts of transplant immunology
Liver Transplantation, EarlyView.
Amanda Cheung, Josh Levitsky
wiley +1 more source
Pathophysiology of sepsis‐induced cholestasis: A review
Sepsis is a critical condition resulting from the excessive activation of the inflammatory/immune system in response to an infection, with high mortality if treatment is not administered promptly. One of the many possible complications of sepsis is liver
Maria Iuliana Ghenu+4 more
doaj +1 more source