Results 81 to 90 of about 107,736 (386)

Pathophysiology of sepsis‐induced cholestasis: A review

JGH Open, 2022
Sepsis is a critical condition resulting from the excessive activation of the inflammatory/immune system in response to an infection, with high mortality if treatment is not administered promptly. One of the many possible complications of sepsis is liver
Maria Iuliana Ghenu, Dorin Dragoş, Maria Mirabela Manea, Dorin Ionescu, Lucian Negreanu   +4 more
doaj   +1 more source

Idiopathic neonatal haemochromatosis: A case report [PDF]

, 2011
A case of neonatal hemochromatosis is reported in a premature 35-week infant who presented at birth with coffee ground vomiting and gradual appearance of grayish icter and colorless stool.
Alaee, E., Besharat, S., Zahedpasha, Y.
core   +1 more source

Expanding etiology of progressive familial intrahepatic cholestasis

World Journal of Hepatology, 2019
BACKGROUND Progressive familial intrahepatic cholestasis (PFIC) refers to a disparate group of autosomal recessive disorders that are linked by the inability to appropriately form and excrete bile from hepatocytes, resulting in a hepatocellular form of ...
Sarah A F Henkel, Judy H. Squires, M. Ayers, A. Ganoza, P. McKiernan, J. Squires   +5 more
semanticscholar   +1 more source

Therapeutic targeting of myeloid cells in liver fibrosis: Mechanisms and clinical prospects

Animal Models and Experimental Medicine, EarlyView.
This review systematically summarizes the origin, recruitment, and differentiation regulation mechanisms of myeloid cells in driving hepatic fibrosis progression. By targeting these three critical phases, potential therapeutic strategies for liver fibrosis can be explored.
Yue Wang, Yiming Liu, Dan Chen, Leiming Liu, Leimin Sun, Lingling Zhang   +5 more
wiley   +1 more source

Effects of cytomegalovirus infection on the differential diagnosis between biliary atresia and intrahepatic cholestasis in a Chinese large cohort study

Annals of Hepatology, 2021
Introduction and objectives: Differentiating biliary atresia from other causes of neonatal cholestasis is challenging, particularly when cytomegalovirus (CMV) and biliary atresia occur simultaneously.
Dongying Zhao, Xiaohui Gong, Yahui Li, Xiaoang Sun, Yan Chen, Zhaohui Deng, Yongjun Zhang   +6 more
doaj  

Preventive effect of ursodeoxycholic acid on parenteral nutrition-associated liver disease in infants [PDF]

Srpski Arhiv za Celokupno Lekarstvo, 2014
Introduction. Parenteral nutrition-associated cholestasis is well recognized phenomenon in the term and preterm infant receiving long-term parenteral nutrition. Objectives. The aim of this study was to evaluate the effect of ursodeoxycholic acid
Simić Dušica, Milojević Irina, Bogićević Dragana, Milenović Miodrag, Radlović Vladimir, Drašković Biljana, Uram-Benka Anna, Sinđić Sanja, Maksimović Ružica   +8 more
doaj   +1 more source

Paeoniflorin alleviates 17α-ethinylestradiol-induced cholestasis via the farnesoid X receptor-mediated bile acid homeostasis signaling pathway in rats

Frontiers in Pharmacology, 2022
Cholestasis, characterized by disturbance of bile formation, is a common pathological condition that can induce several serious liver diseases. As a kind of trigger, estrogen-induced cholestasis belongs to drug-induced cholestasis.
Rulin Wang, Rulin Wang, Tengteng Yuan, Tengteng Yuan, Jing Sun, Menghuan Yang, Menghuan Yang, Yunna Chen, Yunna Chen, Lei Wang, Lei Wang, Yanyan Wang, Yanyan Wang, Weidong Chen, Weidong Chen, Daiyin Peng, Daiyin Peng   +16 more
doaj   +1 more source

Deficiency of Capicua disrupts bile acid homeostasis [PDF]

, 2018
Capicua (CIC) has been implicated in pathogenesis of spinocerebellar ataxia type 1 and cancer in mammals; however, the in vivo physiological functions of CIC remain largely unknown.
Choi, N, Fryer, JD, Hwang, D, Jung, HY, Kang, H, Kim, E, KIM, KYONG TAI, Kim, S, Lee, J, LEE, YOONTAE, Park, S, Yoe, J, Zoghbi, HY   +12 more
core   +2 more sources

The Role of Five‐Membered Aromatic Rings Containing N and O in Modulating Bile Acid Receptors: An Overview

ChemMedChem, EarlyView.
Several derivatives incorporating five‐membered aromatic rings are described in this review as bile acid receptor modulators, particularly targeting the farnesoid X receptor and the G protein‐coupled bile acid receptor 1. This review provides a comprehensive analysis of patents and literature that is useful to support researchers in the design of new ...
Claudia Finamore, Carmen Festa, Rosa Barbato, Stefano Fiorucci, Angela Zampella, Simona De Marino   +5 more
wiley   +1 more source

Cholestasis: human disease and experimental animal models

Annals of Hepatology, 2003
Cholestasis may result from a failure in bile secretion in hepatocytes or ductular cells, or from a blockade to the free bile flow. Human cholestasis may be induced by many drugs, being antibiotics the more common.
Emilio Alberto Rodríguez-Garay, MD, PhD
doaj