Results 1 to 10 of about 6,957 (157)
Hearing Preservation After Segmental Semicircular Canal Destruction: A Report of Two Rare Cases. [PDF]
Clin Case RepABSTRACT Semicircular canal fistulas are a complication of cholesteatomatous otitis media. In extremely rare cases, extensive destruction of the bony labyrinth may result in loss of approximately one‐third of the semicircular canal arc, often with wide exposure and partial injury to the membranous labyrinth, thereby increasing the risk of profound ...
Miwa T +6 more
europepmc +2 more sources
Menin-MLL inhibitors as a new therapeutic target for middle ear cholesteatoma [PDF]
Scientific ReportsMiddle ear cholesteatoma (cholesteatoma), also known as a cholesteatomatous chronic otitis media, is concerning because it expands into the middle ear with bone destruction and causes irreversible hearing loss.
Tomomi Yamamoto-Fukuda +2 more
doaj +2 more sources
Increased Risk of Cholesteatoma in Individuals With Alpha-1 Antitrypsin Deficiency: A Cohort Study. [PDF]
LaryngoscopePatients with AATD had a 3.6‐fold increased risk of cholesteatoma surgery (HR: 3.62) compared to controls. These findings suggest that AATD may contribute to the development of cholesteatoma. ABSTRACT Objective To estimate the risk of cholesteatoma in patients with alpha‐1 antitrypsin deficiency (AATD) compared to the general population using time‐to ...
Ali A, Ravn HA, Dahl M, Djurhuus BD.
europepmc +2 more sources
The significance of the expression of cell proliferation and inflammation markers in the development of acquired middle ear cholesteatoma [PDF]
Vojnosanitetski Pregled, 2018 Background/Aim. Permanent proliferation and periodical infection are the main clinical characteristics of acquired middle ear cholesteatoma. The aim of this study was to research immunohistochemical characteristics of the skin along with the ...
Erdoglija Milan +5 more
doaj +1 more source
Use of artificial intelligence for the diagnosis of cholesteatoma
Laryngoscope Investigative Otolaryngology, 2023 Objectives Accurate diagnosis of cholesteatomas is crucial. However, cholesteatomas can easily be missed in routine otoscopic exams. Convolutional neural networks (CNNs) have performed well in medical image classification, so we evaluated their use for ...
Christopher C. Tseng +2 more
doaj +1 more source
Establishment and Characterization of an Model for Cholesteatoma [PDF]
Clinical and Experimental Otorhinolaryngology, 2008 ObjectivesExperimental models are of importance to study the pathogenesis of middle ear cholesteatoma, however, they were not established until now.
Alexander M. Raynov +4 more
doaj +1 more source
Congenital cholesteatoma [PDF]
Current Opinion in Otolaryngology & Head and Neck Surgery, 2004 Congenital cholesteatomas have historically been considered a rare disorder. However, a review of the literature reveals an incidence ranging from 4 to 24%, and these values are probably underestimated. This article summarizes the general diagnostic criteria of congenital cholesteatomas, their usual presenting symptoms and findings, perioperative ...
Ken, Kazahaya, William P, Potsic
openaire +4 more sources
BioMedical Engineering OnLine, 2021 Background Middle ear cholesteatoma is characterized by hyper-proliferation of keratinocytes. Circular RNA (circRNA) plays an essential role in the pathogenesis of many proliferative diseases.
Shumin Xie +4 more
doaj +1 more source
Cytokeratin 13, Cytokeratin 17, and Ki-67 Expression in Human Acquired Cholesteatoma and Their Correlation With Its Destructive Capacity [PDF]
Clinical and Experimental Otorhinolaryngology, 2017 Objectives Cholesteatoma is a nonneoplastic destructive lesion of the temporal bone with debated pathogenesis and bone resorptive mechanism. Both molecular and cellular events chiefly master its activity.
Mahmood A. Hamed +11 more
doaj +1 more source
Philippine Journal of Otolaryngology Head and Neck Surgery, 2021 Objective: To determine the stage of middle ear cholesteatoma of patients who underwent middle ear surgery at the Southern Philippines Medical Center from January to December 2019, based on European Academy of Otology and Neurotology / Japan ...
Dominador Toral, Chris Robinson Laganao
doaj +1 more source