Results 1 to 10 of about 13,086 (214)

Identification of Differential Metabolites in Chronic Suppurative Otitis Media With Non-Targeted and Targeted Metabolomics Approach. [PDF]

Smart Med
Untargeted metabolomics is used to analyze tissue samples from chronic suppurative otitis media patients with or without cholesteatoma and identify metabolic differences across groups stratified by CT scores. Targeted metabolomic validation in an independent cohort verified five candidate metabolites. ABSTRACT Chronic suppurative otitis media (CSOM) is
Hu L, Zhu Y, Wu C, Liu X, Wang Q, Huang Y, Liu H, Chen X, Wu W, Jiang H.   +9 more
europepmc   +2 more sources

Rigid Autofluorescence Imaging as a Tool for Identifying Cholesteatoma During Otologic Surgery: Initial Ex Vivo Findings. [PDF]

Otolaryngol Head Neck Surg
Abstract Objective This study aims to determine whether rigid autofluorescence imaging can differentiate cholesteatoma from surrounding tissues to reduce residual disease after cholesteatoma surgery. Study Design Ex vivo proof‐of‐principle study. Setting Erasmus University Medical Center, Rotterdam, the Netherlands.
van der Toom HFE, de Bruijn HS, Pauw RJ, Koljenović S, Koppes S, Robinson DJ, Keereweer S.   +6 more
europepmc   +2 more sources

Expression of periostin in the epithelium of cholesteatoma with different degrees of ossicular chain destruction and its clinical value in predicting postoperative hearing recovery [PDF]

BioMedical Engineering OnLine
Objectives To explore the expression of periostin in the epithelium of cholesteatoma with different destruction degrees of the ossicular chain and its clinical value in predicting postoperative hearing recovery.
Cuncun Xie, Xiaodong Jia, Shaoguang Ding, Xiaoli Ding, Guangke Wang, Hongjian Liu   +5 more
doaj   +2 more sources

The significance of the expression of cell proliferation and inflammation markers in the development of acquired middle ear cholesteatoma [PDF]

Vojnosanitetski Pregled, 2018
Background/Aim. Permanent proliferation and periodical infection are the main clinical characteristics of acquired middle ear cholesteatoma. The aim of this study was to research immunohistochemical characteristics of the skin along with the ...
Erdoglija Milan, Grgurević Uglješa, Cerović Snežana, Jović Milena, Baletić Nenad, Sotirović Jelena   +5 more
doaj   +1 more source

Establishment and Characterization of an Model for Cholesteatoma [PDF]

Clinical and Experimental Otorhinolaryngology, 2008
ObjectivesExperimental models are of importance to study the pathogenesis of middle ear cholesteatoma, however, they were not established until now.
Alexander M. Raynov, Yun-Hoon Choung, Hun Yi Park, Seong Jun Choi, Keehyun Park   +4 more
doaj   +1 more source

Use of artificial intelligence for the diagnosis of cholesteatoma

Laryngoscope Investigative Otolaryngology, 2023
Objectives Accurate diagnosis of cholesteatomas is crucial. However, cholesteatomas can easily be missed in routine otoscopic exams. Convolutional neural networks (CNNs) have performed well in medical image classification, so we evaluated their use for ...
Christopher C. Tseng, Valerie Lim, Robert W. Jyung   +2 more
doaj   +1 more source

Classification and Stages of Middle Ear Cholesteatoma at the Southern Philippines Medical Center Using the European Academy of Otology and Neurotology / Japan Otological Society (EAONO / JOS) System

Philippine Journal of Otolaryngology Head and Neck Surgery, 2021
Objective: To determine the stage of middle ear cholesteatoma of patients who underwent middle ear surgery at the Southern Philippines Medical Center from January to December 2019, based on European Academy of Otology and Neurotology / Japan ...
Dominador Toral, Chris Robinson Laganao
doaj   +1 more source

Neuroradiology of Cholesteatomas [PDF]

American Journal of Neuroradiology, 2010
The relevant aspects of cholesteatomas are reviewed with the emphasis on their diagnosis by using cross-sectional imaging. The indications and limitations of CT and MR imaging and the use of novel MR imaging techniques in the diagnosis of cholesteatomas are described.
Baráth, K, Huber, A M, Stämpfli, Philipp, Varga, Z, Kollias, S   +4 more
openaire   +3 more sources

Microarray analysis and functional prediction of differentially expressed circular RNAs in acquired middle ear cholesteatoma

BioMedical Engineering OnLine, 2021
Background Middle ear cholesteatoma is characterized by hyper-proliferation of keratinocytes. Circular RNA (circRNA) plays an essential role in the pathogenesis of many proliferative diseases.
Shumin Xie, Li Jin, Tuanfang Yin, Jihao Ren, Wei Liu   +4 more
doaj   +1 more source

Cytokeratin 13, Cytokeratin 17, and Ki-67 Expression in Human Acquired Cholesteatoma and Their Correlation With Its Destructive Capacity [PDF]

Clinical and Experimental Otorhinolaryngology, 2017
Objectives Cholesteatoma is a nonneoplastic destructive lesion of the temporal bone with debated pathogenesis and bone resorptive mechanism. Both molecular and cellular events chiefly master its activity.
Mahmood A. Hamed, Seiichi Nakata, Kazuya Shiogama, Kenji Suzuki, Ramadan H. Sayed, Yoichi Nishimura, Noboru Iwata, Kouhei Sakurai, Badawy S. Badawy, Ken-ichi Inada, Hayato Tsuge, Yutaka Tsutsumi   +11 more
doaj   +1 more source