Establishment and Characterization of an Model for Cholesteatoma [PDF]
Clinical and Experimental Otorhinolaryngology, 2008 ObjectivesExperimental models are of importance to study the pathogenesis of middle ear cholesteatoma, however, they were not established until now.
Alexander M. Raynov +4 more
doaj +5 more sources
Expression of CYLD and NF-κB in Human Cholesteatoma Epithelium [PDF]
Mediators of Inflammation, 2010 The tumor suppressor CYLD is a deubiquitinating enzyme that inhibits activation of the NF-κB, which has key roles in inflammation and apoptosis. We hypothesized that CYLD may regulate the NF-κB signaling pathway in cholesteatoma.
Jae Yong Byun +4 more
doaj +4 more sources
A Retrospective Analysis and Comparison of the STAM and STAMCO Classification and EAONO/JOS Cholesteatoma Staging System in Predicting Surgical Treatment Outcomes of Middle Ear Cholesteatoma [PDF]
Otology and Neurotology, 2020 OBJECTIVE: To evaluate and compare the STAM classification, STAMCO classification and the EAONO/JOS staging system as predictors for cholesteatoma recidivism and postoperative hearing, using a large patient cohort in our tertiary referral center. METHOD:
Janssen, J. (Jmh) +4 more
core +3 more sources
Transcanal Endoscopic Ear Surgery for Congenital Cholesteatoma [PDF]
Clinical and Experimental Otorhinolaryngology, 2018 Objectives As endoscopic instrumentation, techniques and knowledges have significantly improved recently, endoscopic ear surgery has become increasingly popular. Transcanal endoscopic ear surgery (TEES) can provide better visualization of hidden areas in
Joo Hyun Park, Jungmin Ahn, Il Joon Moon
doaj +2 more sources
Chronic inflammation of middle ear cholesteatoma promotes its recurrence via a paracrine mechanism
Cell Communication and Signaling, 2021 Background Cholesteatoma disease is an expanding lesion in the middle ear. Hearing loss and facial paralysis alongside with other intracranial complications are found.
Matthias Schürmann +7 more
doaj +2 more sources
Outcomes in Pediatric Cholesteatoma. [PDF]
Otolaryngol Head Neck SurgAbstract Objective The objective of the study is to evaluate the outcomes of surgical management options for cholesteatoma using a national database. Study Design Database analysis of the Pediatric Health Information System database to identify children undergoing surgical intervention for cholesteatoma from October 2015 to December 2022.
Miller KM +5 more
europepmc +2 more sources
ADC Benchmark Range for Correct Diagnosis of Primary and Recurrent Middle Ear Cholesteatoma [PDF]
BioMed Research International, 2018 Objectives. Magnetic resonance imaging (MRI) and in particular diffusion-weighted imaging (DWI) have been broadly proven to be the reference imaging method to discriminate between cholesteatoma and noncholesteatomatous middle ear lesions, especially when
Brunetti, Arturo +7 more
core +3 more sources
Cholesteatoma vs granulation tissue: a differential diagnosis by DWI-MRI apparent diffusion coefficient [PDF]
European Archives of Oto-Rhino-Laryngology, 2018 To diagnose cholesteatoma when it is not visible through tympanic perforation, imaging techniques are necessary. Recently, the combination of computed tomography and magnetic resonance imaging has proven effective to diagnose middle ear cholesteatoma. In
Brunetti, L +8 more
core +2 more sources
EAONO/JOS, STAMCO, ChOLE & Potsic Staging of 271 Pediatric Cholesteatoma: Evidence-Based Mod-Pot Staging System. [PDF]
LaryngoscopeWe assess the EAONO/JOS, STAMCO, ChOLE, and Potsic cholesteatoma grading systems in a large pediatric cohort with at least 5‐year follow‐up. Based on evidence, we put forward a Mod‐Pot (modified Potsic) system which better predicts cholesteatoma recividism and auditory outcomes in the child.
Marchand G +9 more
europepmc +2 more sources
Remodeling Factors, Transcription Factors and Angiogenetic Factors in Cholesteatoma in Ontogenetic Aspect [PDF]
Iranian Journal of Otorhinolaryngology, 2022 Introduction:The main goal of our study was to describe the transcription factor (NF-κβ), angiogenetic factor (VEGF), and remodeling markers (MMP-9 and TIMP-4) of the cholesteatoma tissue compared to control skin tissue. There are still uncertainties how
Kristaps Dambergs +2 more
doaj +4 more sources