Increased Risk of Cholesteatoma in Individuals With Alpha‐1 Antitrypsin Deficiency: A Cohort Study
Patients with AATD had a 3.6‐fold increased risk of cholesteatoma surgery (HR: 3.62) compared to controls. These findings suggest that AATD may contribute to the development of cholesteatoma. ABSTRACT Objective To estimate the risk of cholesteatoma in patients with alpha‐1 antitrypsin deficiency (AATD) compared to the general population using time‐to ...
Abdulla Ali +3 more
wiley +1 more source
Use of Endoscopic Ear Surgery as Adjunct to Microscopic Surgery in Cholesteatoma Surgery
This study was conducted to review the value of endoscopic ear surgery as adjunct to microscopic surgery in management of cholesteatoma. It aimed to determine the accessibility of hidden sites and to assess surgical outcomes in cholesteatoma surgery with
Camille Levie, Patrick Levie
doaj +1 more source
Diagnosis of recurrent cholesteatoma using diffusion weighted MRI
Objective: To assess the role of diffusion weighted images (DWI) MRI in differentiating post mastoidectomy recurrent cholesteatoma from infected postoperative granulation tissue. Materials and methods: 13 patients who performed mastoidectomy for previous
Ahmed Fathy Abdel Ghany
doaj +1 more source
Chronic inflammation of middle ear cholesteatoma promotes its recurrence via a paracrine mechanism
Background Cholesteatoma disease is an expanding lesion in the middle ear. Hearing loss and facial paralysis alongside with other intracranial complications are found.
Matthias Schürmann +7 more
doaj +1 more source
Malleostapedotomy in Patients With Stapes Fixation: A Systematic Review
This systematic review analyses the current evidence on malleostapedotomy as a primary or revision procedure in patients with stapes fixation. Twenty‐five studies comprising 632 operated ears were included. Malleostapedotomy proved to be a safe and effective alternative to incus‐anchoring stapedoplasty, with favorable hearing outcomes and a low ...
Matteo Alicandri‐Ciufelli +4 more
wiley +1 more source
Middle ear tuberculosis: Diagnostic criteria [PDF]
Introduction. Tuberculous otitis is a diagnostic problem due to the difficulty to obtain microbiological, histomorphological and cytological confirmation of the disease. Objective. Our objective was to compare clinical and radiological characteristic and
Dudvarski Zoran +6 more
core +1 more source
Abstract Objective To evaluate the petrosquamous septum in children under 5 years of age and its usefulness as a surgical landmark using computed tomography (CT); to identify petrosquamous stalactite and its relationship to the ossicular chain and external acoustic meatus is also described. Study Design Retrospective review of CT scans.
Tomasz Wojciechowski +2 more
wiley +1 more source
Labyrinthine fístulae in chronic otitis media with cholesteatoma [PDF]
The chronic otitis media with cholesteatoma (COMC) may evoluate to intracranial and extra cranial complications, including the labyrithine fístulae. In this study, we present the evolution of our patients with labyrinthine fístulae.
Abreu, Carlos E.c. +5 more
core +5 more sources
The Global Burden of Cholesteatoma: A Systematic Review and Meta‐analysis
Abstract Objective This systematic review and meta‐analysis sought to estimate the global and World Health Organization (WHO) regional prevalence and burden of cholesteatoma. Data Sources PubMed, APA PsycINFO, the Cochrane Library, Embase, and WHO International Clinical Trials Registry Platform (ICTRP) from 2010 to 2025.
Herbert Melariri +21 more
wiley +1 more source
Large-scale proteomics differentiates cholesteatoma from surrounding tissues and identifies novel proteins related to the pathogenesis. [PDF]
Cholesteatoma is the growth of keratinizing squamous epithelium in the middle ear. It is associated with severe complications and has a poorly understood etiopathogenesis.
Anders Britze +4 more
doaj +1 more source

