Results 141 to 150 of about 981,314 (303)

Ixekizumab With Tirzepatide Achieved Greater Disease Control Than Ixekizumab Alone in Adults With Psoriatic Arthritis and Overweight or Obesity: Results From a Randomized Clinical Trial

Arthritis &Rheumatology, EarlyView.
Objective Overweight or obesity is prevalent in 72% to 82% of individuals with psoriatic arthritis (PsA). We assessed the efficacy and safety of ixekizumab (IXE) concomitantly administered with tirzepatide (TZP) compared with IXE alone in adult participants with active PsA and overweight with at least one weight‐related comorbidity or obesity.
Joseph F. Merola, Philip Mease, Alan Kivitz, Naveed Sattar, Laura C. Coates, Daniel Aletaha, Cynthia E. Kartman, Peter Fischer, Luna Sun, Píndaro Martínez‐Osuna, Andris Kronbergs, Purvi Prajapati, Anabela Cardoso, Mark C. Genovese, Alexis Ogdie   +14 more
wiley   +1 more source

T cells, the Next Big Target in Axial Spondyloarthritis?

Arthritis &Rheumatology, EarlyView.
Axial spondyloarthritis (axSpA) is a chronic inflammatory disease characterized by complex immune dysregulation, with T cells playing a central role in its pathogenesis. In this review, we synthesize current knowledge on diverse T cell subsets in axSpA, their pathogenic mechanisms, and emerging therapeutic strategies targeting these cells. We highlight
Mansi K. Aparnathi, Nigil Haroon
wiley   +1 more source

EFFECTS OF DIETARY CALCIUM ON CONCENTRATIONS OF LIPIDS, GLUCOSE AND INSULIN IN MALE SPRAGUE-DAWELY RATS

ARYA Atherosclerosis, 2010
  Abstract INTRODUCTION: A number of experimental studies have shown that dietary calcium may help improve hypercholesterolemia induced by high-cholesterol/high-fat diets through saponifying cholesterol/fat in the intestine.
Jan Mohammd Malekzadeh, Ali Keshavarz, Feridon Siassi, Mehri Kadkhodaei, Mohammad Reza Eshraghian, Ahmad Reza Dorosti-Motlagh, Asghar Aliehpoor, Maryam Chamari   +7 more
doaj  

New therapeutic options for metabolic‐associated steatotic liver disease

British Journal of Clinical Pharmacology, EarlyView.
An increasing number of patients are being diagnosed with metabolic dysfunction‐associated steatotic liver disease (MASLD). MASLD results from disturbances in hepatic lipid metabolism and is associated with an increased risk of cirrhosis and hepatocellular carcinoma and significant extrahepatic morbidity, including cardiovascular disease and ...
Tessa Straatmijer, Midas Mulder
wiley   +1 more source

How to control your fat and cholesterol : how to control your cholesterol numbers

Raymundo and his family would like to invite you to read this fotonovela and learn about how to control fat and cholesterol in your diet. This fotonovela can be used by many community health workers and Promotoras de Salud to help people control their ...

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Hypertension in obesity: A focus on individualized pharmacotherapy and the role of body composition, on behalf of the European Society of Hypertension Working Group on Diabetes and Metabolic Risk Factors and Working Group on Lifestyle, Cardiovascular Pharmacotherapy and Adherence

British Journal of Clinical Pharmacology, EarlyView.
Hypertension in obesity represents a major global health challenge, closely linked to the global epidemics of obesity, type 2 diabetes and metabolic dysfunction. Excess adiposity contributes to elevated blood pressure through multiple, interrelated mechanisms, including activation of the renin–angiotensin–aldosterone system, sympathetic nervous system ...
Christina Antza, Andrej Belancic, Jens Jordan, Alberto Esteban, Anna Oliveras, Ryan McNally, Panagiota Anyfanti, Jorie Versmissen, María S. Fernández‐Alfonso, Vasilios Kotsis, Thomas Weber, Alexandre Persu, Reinhold Kreutz   +12 more
wiley   +1 more source

How to control your fat and cholesterol : how to control your cholesterol numbers [Spanish]

Oton\ucc\u192o 2013How to control your fat and cholesterol : how to control your cholesterol numbers [Spanish]Raymundo y su familia quieren invitarlo a que lea esta fotonovela y aprenda sobre co\ucc?mo controlar la grasa y el colesterol en su dieta. Esta

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Clinical relevance of pharmacogenomic information for improving prescribing practices in acutely admitted older medical patients

British Journal of Clinical Pharmacology, EarlyView.
Aims Safe prescribing and effective medication review during acute hospitalization depends on accurate information about liver and kidney function because these organs are responsible for the elimination of most medications. While estimates for kidney function are widely used, comparable markers of hepatic drug‐metabolizing capacity are not routinely ...
Louise Westberg Strejby Christensen, Anne Kirstine Boas, Emilie Clausen, Nicoline Elers Koch, Anne Byriel Walls, Lotte Stig Nørgaard, Michael Asger Andersen, Anissa Aharaz, Rikke Lundsgaard Nielsen, Olivia Bornæs, Juliette Tavenier, Baker Nawfal Jawad, Helle Gybel Juul‐Larsen, Esben Iversen, Ove Andersen, Lona Louring Christrup, Kim Peder Dalhoff, Morten Baltzer Houlind   +17 more
wiley   +1 more source

Cholesterol Dietary Intake and Tumor Cell Homeostasis Drive Early Epithelial Tumorigenesis: A Potential Modelization of Early Prostate Tumorigenesis. [PDF]

Cancers (Basel)
Vialat M, Baabdaty E, Trousson A, Kocer A, Lobaccaro JA, Baron S, Morel L, de Joussineau C.   +7 more
europepmc   +1 more source

Promotora guide : How to control your fat and cholesterol : how to control your cholesterol numbers

We hope you like the fotonovela, \ue2\u20ac\u153How to Control your fat, and cholesterol.\ue2\u20ac\u153 This fotonovela is number 3 of the series starting with \ue2\u20ac\u153Co\ucc?mo controlar su hipertensio\ucc?n.\ue2\u20ac?

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