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Dietary cholesterol, membrane cholesterol and cholesterol synthesis

Biochimie, 1991
After describing the main steps of cholesterol biosynthesis the author recalls that the cholesterogenesis rate is feedback-inhibited by dietary cholesterol and examines the various processes of modulation. Hydroxy-3-methylglutaryl (HMG) CoA reductase, the key rate-limiting enzyme, is a 97 kDa endoplasmic reticulum glycoprotein, anchored 7-fold in this ...
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DIETARY CHOLESTEROL AND PLASMA CHOLESTEROL LEVELS IN MAN

Canadian Journal of Biochemistry and Physiology, 1959
Sixty-three men and twenty women (university students) consumed a fat-free, homogeneous liquid formula ration for 8 days. Groups of 8 to 11 individuals were then transferred to diets in which 30% of the calories were supplied in the form of butter oil fractions which were substituted equicalorically for carbohydrate.
J M, BEVERIDGE   +3 more
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Rethinking dietary cholesterol

Current Opinion in Clinical Nutrition and Metabolic Care, 2012
The perceived notion that dietary cholesterol is associated with increased risk for coronary heart disease (CHD) has led to dietary recommendations of no more than 300  mg/day for healthy populations in the USA. This study will review the recent evidence that challenges the current dietary restrictions regarding cholesterol while it presents some ...
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Dietary cholesterol and atherosclerosis

Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, 2000
The perceived relationship between dietary cholesterol, plasma cholesterol and atherosclerosis is based on three lines of evidence: animal feeding studies, epidemiological surveys, and clinical trials. Over the past quarter century studies investigating the relationship between dietary cholesterol and atherosclerosis have raised questions regarding the
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Dietary cholesterol and plasma lipoproteins

Atherosclerosis, 1993
Although dietary cholesterol undoubtedly affects the plasma cholesterol level, the magnitude of this effect depends on several factors: 1. the amount of cholesterol ingested; 2. the amount of dietary fat; 3. the type of dietary fat; 4. the efficiency of metabolic compensatory mechanisms; 5. interactions with other dietary factors. Some of these are not
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