Results 91 to 100 of about 927,420 (325)

The cardiovascular phenotype of adult patients with phenylketonuria [PDF]

, 2019
BACKGROUND: Patients with Phenylketonuria (PKU) are exposed to multiple cardiovascular risk factors, but the clinical significance of these abnormalities is yet unknown.
Azabdaftari, Aline, Giet, Markus van der, Hennermann, Julia B., Plöckinger, Ursula, Querfeld, Uwe, Schuchardt, Mirjam   +5 more
core   +1 more source

Programmable Pentamolecular Cross‐Scale Imaging Reveals the Multiplicative Synergistic Effect of High‐Fat / High‐Salt Diet on Atherosclerosis

Advanced Science, EarlyView.
This study demonstrates multifactorial lifestyle impacts on the pathogenesis and progression of cardiovascular diseases by a nanofluorescence sensor array for detecting four redox species and protein phosphorylation levels. Through cross‐scale fluorescence imaging of rats with different diets, we revealed that compared with single dietary interventions,
Jin Li, Na Zhao, Mengmeng Lu, Ruize Zhao, Wei Zhang, Ping Li, Yue Tang, Wen Zhang, Hui Wang, Bo Tang   +9 more
wiley   +1 more source

Distribution and Correlations of Non-High-Density Lipoprotein Cholesterol in Roma and Caucasian Children: The Slovak Lipid Community Study [PDF]

, 2009
Non-high-density lipoprotein (non-HDL) cholesterol [total cholesterol minus high-density lipoprotein (HDL) cholesterol] is considered a better predictor of coronary heart disease (CHD) risk than low-density lipoprotein (LDL) cholesterol.
Dáša Albertyová, Ivan Ahlers, Roman Alberty   +2 more
core   +1 more source

Free cholesterol transfer to high-density lipoprotein (HDL) upon triglyceride lipolysis underlies the U-shape relationship between HDL-cholesterol and cardiovascular disease

European Journal of Preventive Cardiology, 2019
Background Low concentrations of high-density lipoprotein cholesterol (HDL-C) represent a well-established cardiovascular risk factor. Paradoxically, extremely high HDL-C levels are equally associated with elevated cardiovascular risk, resulting in the U-
Ma Feng, M. Darabi, E. Tubeuf, A. Canicio, M. Lhomme, E. Frisdal, Sandrine Lanfranchi-Lebreton, L. Mathéron, F. Rached, M. Ponnaiah, C. Serrano, R. Santos, F. Brites, G. Bolbach, E. Gautier, T. Huby, A. Carrié, E. Bruckert, M. Guerin, P. Couvert, P. Giral, P. Lesnik, W. Le Goff, I. Guillas, A. Kontush   +24 more
semanticscholar   +1 more source

From the Gut to the Brain: Microplastic‐Associated Neurovascular Dysfunction and Implications for Stroke Risk

Advanced Science, EarlyView.
Chronic oral exposure to microplastics may disrupt gut microbiota homeostasis and intestinal barrier integrity, potentially engaging the gut–brain axis and systemic inflammatory responses. These alterations may be associated with impaired blood–brain barrier function, cerebral microvascular dysfunction, and enhanced endothelial inflammation, pro ...
Hongxing Wang, Yujiao He, Pei Zou, Xiaoyi Wang, Gang Peng, Xiangying Deng   +5 more
wiley   +1 more source

Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity. [PDF]

, 2019
Many genetic loci affect circulating lipid levels, but it remains unknown whether lifestyle factors, such as physical activity, modify these genetic effects.
Alver, Maris, Amin, Najaf, Amini, Marzyeh, Arnett, Donna K, Aschard, Hugues, Aslibekyan, Stella, Bartz, Traci M, Bentley, Amy R, Bielak, Lawrence F, Boerwinkle, Eric, Boissel, Mathilde, Brown, Michael R, Brumat, Marco, Cade, Brian, Campbell, Archie, Canouil, Mickaël, Chai, Jin Fang, Chasman, Daniel I, Chen, Xu, Chen, Yii-Der Ida, Concas, Maria Pina, Connell, John, de Las Fuentes, Lisa, de Mutsert, Renée, de Silva, H Janaka, de Vries, Paul S, Demirkan, Ayşe, Ding, Jingzhong, Divers, Jasmin, Dorajoo, Rajkumar, Eaton, Charles B, Evangelou, Evangelos, Faul, Jessica D, Feitosa, Mary F, Fisher, Virginia, Franceschini, Nora, Friedlander, Yechiel, Gabriel, Kelley P, Gao, Chuan, Ghanbari, Mohsen, Giulianini, Franco, Graff, Mariaelisa, Gu, Chi Charles, Gu, Dongfeng, Guo, Xiuqing, Harris, Sarah E, Harris, Tamara B, Hartwig, Fernando P, He, Jiang, He, Meian, Heikkinen, Sami, Heng, Chew-Kiat, Horimoto, Andrea RVR, Hsu, Fang-Chi, Hunt, Steven C, Ikram, M Arfan, Jackson, Anne U, Jakupović, Hermina, Jonas, Jost B, Kho, Minjung, Kilpeläinen, Tuomas O, Koh, Woon-Puay, Komulainen, Pirjo, Kraja, Aldi T, Krieger, Jose E, Kühnel, Brigitte, Laguzzi, Federica, Li, Changwei, Li, Xiaoyin, Lohman, Kurt K, Lyytikäinen, Leo-Pekka, Manning, Alisa, Marten, Jonathan, Musani, Solomon K, Nolte, Ilja M, Noordam, Raymond, Ntalla, Ioanna, Rauramaa, Rainer, Riaz, Muhammad, Richard, Melissa, Robino, Antonietta, Rueedi, Rico, Schwander, Karen, Sim, Xueling, Smith, Albert V, Stringham, Heather M, Sung, Yun Ju, Tajuddin, Salman M, Takeuchi, Fumihiko, van der Most, Peter J, Varga, Tibor V, Verweij, Niek, Vojinovic, Dina, Wang, Heming, Wang, Zhe, Ware, Erin B, Wen, Wanqing, Winkler, Thomas W, Yanek, Lisa R, Zhao, Jing Hua   +99 more
core  

Rural to Urban Migration and Changes in Cardiovascular risk Factors in Tanzania: A Prospective Cohort Study. [PDF]

, 2010
High levels of rural to urban migration are a feature of most African countries. Our aim was to investigate changes, and their determinants, in cardiovascular risk factors on rural to urban migration in Tanzania.
AB Swai, BM Popkin, Bushiri Tamin, DA Leon, DG McLarty, Dorothy McLarty, G Chahoud, Harun Machybia, HH Vorster, HM Kitange, JA Marshall, M Tanner, Mkay Nguluma, N Unwin, N Unwin, N Unwin, Nigel Unwin, NR Poulter, NR Poulter, P Bovet, P Setel, Peter James, Peter Nkulila, Population Division of the Department of Economic and Social Affairs, R Edwards, RA McLean, Richard McNally, RW Walker, SAS Institute Inc, TJ Aspray, United Nations Population Division, WT Friedewald   +31 more
core   +2 more sources

Cholesterol Promotes Lung Adenocarcinoma Brain Metastasis by Stabilizing EGFR Protein to Drive EMT, Metabolic Reprogramming, and Premetastatic Niche Formation

Advanced Science, EarlyView.
Cholesterol is revealed as a multitasking fuel for lung adenocarcinoma brain metastasis: it locks EGFR at the membrane to sustain AKT/NF‐κB–driven glycolysis and EMT, loosens the blood–brain barrier by promoting Claudin‐5 loss, and rewires microglia through IL‐4R lipid‐raft–JAK1/STAT6 signaling.
Ying Chen, Xiaoteng Cui, Xinyi Shi, Xu Yang, Yujing Cao, Haolin LI, Qi Zhan, Qixue Wang, Ang Li, Qihong Cheng, Yunfei Wang, Junhu Zhou, MingJie Wang, Chunsheng Kang, Xiaomin Liu   +14 more
wiley   +1 more source

Relationship of the parameters of body cholesterol metabolism with plasma levels of HDL cholesterol and the major HDL apoproteins.

Journal of Lipid Research, 1985
The inverse relationship between plasma levels of high density lipoprotein (HDL) and coronary heart disease rates has suggested that HDL might influence body stores of cholesterol.
C B Blum, R B Dell, R H Palmer, R Ramakrishnan, A H Seplowitz, D S Goodman   +5 more
doaj   +1 more source

Occupational Physical Activity and Cardiovascular Risk Factors Profile in the Adult Population of the Southern Cone of Latin America: Results From the CESCAS I Study [PDF]

, 2018
OBJECTIVE: We explore the association between occupational physical activity (OPA) and cardiovascular risk factors in four cities of the Southern Cone. METHODS: Robust multivariable linear regression models were used to examine the associations. RESULTS:
Elorriaga, Natalia, Gutierrez, Laura, Irazola, Vilma, Melendi, Santiago Ezequiel, Poggio, Rosana   +4 more
core   +1 more source