Results 221 to 230 of about 392,380 (285)

Obstructive Sleep Apnea Following Bariatric Surgery: 20 Year Outcomes From the Swedish Obese Subjects Study

open access: yesObesity, EarlyView.
ABSTRACT Objective Bariatric surgery has been suggested to improve obstructive sleep apnea (OSA) in short‐term studies, but long‐term evidence is limited. We evaluated remission and new onset of OSA over 20 years in participants from the Swedish Obese Subjects (SOS) study, comparing bariatric surgery with usual obesity care.
Ida Arnetorp   +8 more
wiley   +1 more source

Retatrutide Shows Multiple Metabolic Benefits in Diet‐Induced Obese MASH Mouse and Hamster Models

open access: yesObesity, EarlyView.
ABSTRACT Objective/Methods Our aim was to evaluate the efficacy of the triple glucagon, GIP, and GLP‐1 receptor agonist retatrutide in diet‐induced obese MASH mouse and hamster models, two preclinical models that we routinely use for assessing new therapies targeting obesity.
François Briand   +6 more
wiley   +1 more source

Adipose Tissue‐Derived Small Extracellular Vesicles in Plasma Reveal Molecular Circuitries Underlying Glucose Intolerance

open access: yesObesity, EarlyView.
ABSTRACT Objective Glucose tolerance (GT) is a major effector for adipose tissue (AT) remodeling in obesity, yet its molecular mechanisms remain incompletely defined. We hypothesized that the biophysical and molecular profiles of AT‐derived small extracellular vesicles (sEVAT) change in response to glucose availability and differ by GT status.
Shalini Mishra   +10 more
wiley   +1 more source

Development and Validation of a Nomogram Incorporating Preoperative N‐Terminal Pro‐Brain Natriuretic Peptide to Predict Major Adverse Cardiovascular Events in Renal Transplant Recipients

open access: yesOrgan Medicine, EarlyView.
We developed and validated a preoperative nomogram incorporating NT‐proBNP to predict major adverse cardiovascular events in renal transplant recipients. Using a LASSO‐Cox model based on 582 training and 181 validation cases, we identified NT‐proBNP, age, body mass index, diabetes, and retransplantation as key predictors.
Guobin Wu   +9 more
wiley   +1 more source

Prevalence of non‐alcoholic fatty liver disease and its association with different combinations of weight status and metabolic abnormalities in children aged 6–18 years

open access: yesPediatric Investigation, EarlyView.
Children with non‐overweight combined with metabolic risk factors might increase the risk of non‐alcoholic fatty liver disease (NAFLD). These findings suggest that overweight and obesity should not be the sole criterion for NAFLD screening in children. In particular, more attention should be given to non‐overweight combined with metabolic abnormalities
Peiyu Ye   +22 more
wiley   +1 more source

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