Results 21 to 30 of about 286,346 (314)
Selective delipidation of plasma HDL enhances reverse cholesterol transport in vivo
Uptake of cholesterol from peripheral cells by nascent small HDL circulating in plasma is necessary to prevent atherosclerosis. This process, termed reverse cholesterol transport, produces larger cholesterol-rich HDL that transfers its cholesterol to the
Frank M. Sacks +13 more
doaj +1 more source
Hepatic lipase stimulates the uptake of high density lipoprotein cholesterol by hepatoma cells.
The objective of this study was to determine whether high density lipoproteins (HDL) that have been treated with hepatic lipase have an enhanced ability to deliver cholesterol to cells.
M Bamberger, J M Glick, G H Rothblat
doaj +1 more source
Recently, we showed that holo HDL particle uptake and resecretion occur in physiologically relevant cell lines and that HDL uptake is mediated by scavenger receptor class B type I (SR-BI).
Tamara A. Pagler +4 more
doaj +1 more source
Genetic variants in lipid metabolism are independently associated with multiple features of the metabolic syndrome [PDF]
Background Our objective was to find single nucleotide polymorphisms (SNPs), within transcriptional pathways of glucose and lipid metabolism, which are related to multiple features of the metabolic syndrome (MetS).
Boer, J.M. +14 more
core +1 more source
BACKGROUND: Establishment of inexpensive clinical laboratory tests to evaluate inflammation and oxidative stress is urgently needed in the limited resources settings.
Ika Nindya Kadariswantiningsih +10 more
doaj +1 more source
Paradoxical mortality differential of HDL cholesterol
High-density lipoprotein (HDL) cholesterol has been known for ages to be cardio-protective due to its defensive action against genesis of atherosclerosis.
Jyotishman Mukhopadhyay +2 more
doaj +1 more source
Biophysical characterization of reactions associated with reverse cholesterol transport [PDF]
This thesis aimed at improving our understanding of reactions relevant in the reverse cholesterol transport (RCT). RCT facilitates cholesterol homeostasis and is the most important pathway involved in cardiovascular disease.
Zehender, Fabian
core +1 more source
The High Density Lipoprotein Cholesterol Hypothesis Revisited
BACKGROUND: The strong inverse association of plasma levels of high-density lipoprotein cholesterol (HDL-C) with coronary heart disease (CHD) found in human epidemiological studies led to the development of the ‘HDL-C hypothesis’, which posits that ...
Anna Meiliana +2 more
doaj +1 more source
Apolipoprotein M promotes cholesterol uptake and efflux from mouse macrophages
Apolipoprotein M (ApoM) exhibits various anti‐atherosclerotic functions as a component of high‐density lipoprotein (HDL) particles. Scavenger receptor class B type I (SR‐BI) is a classic HDL receptor that mediates selective cholesterol uptake and ...
Shuang Yao +6 more
doaj +1 more source
Large-Scale Candidate Gene Analysis of HDL Particle Features
Background: HDL cholesterol (HDL-C) is an established marker of cardiovascular risk with significant genetic determination. However, HDL particles are not homogenous, and refined HDL phenotyping may improve insight into regulation of HDL metabolism.
Burton Paul R. +125 more
core +1 more source

