Results 21 to 30 of about 286,346 (314)

Selective delipidation of plasma HDL enhances reverse cholesterol transport in vivo

open access: yesJournal of Lipid Research, 2009
Uptake of cholesterol from peripheral cells by nascent small HDL circulating in plasma is necessary to prevent atherosclerosis. This process, termed reverse cholesterol transport, produces larger cholesterol-rich HDL that transfers its cholesterol to the
Frank M. Sacks   +13 more
doaj   +1 more source

Hepatic lipase stimulates the uptake of high density lipoprotein cholesterol by hepatoma cells.

open access: yesJournal of Lipid Research, 1983
The objective of this study was to determine whether high density lipoproteins (HDL) that have been treated with hepatic lipase have an enhanced ability to deliver cholesterol to cells.
M Bamberger, J M Glick, G H Rothblat
doaj   +1 more source

Cholesterol efflux via HDL resecretion occurs when cholesterol transport out of the lysosome is impaireds⃞

open access: yesJournal of Lipid Research, 2007
Recently, we showed that holo HDL particle uptake and resecretion occur in physiologically relevant cell lines and that HDL uptake is mediated by scavenger receptor class B type I (SR-BI).
Tamara A. Pagler   +4 more
doaj   +1 more source

Genetic variants in lipid metabolism are independently associated with multiple features of the metabolic syndrome [PDF]

open access: yes, 2011
Background Our objective was to find single nucleotide polymorphisms (SNPs), within transcriptional pathways of glucose and lipid metabolism, which are related to multiple features of the metabolic syndrome (MetS).
Boer, J.M.   +14 more
core   +1 more source

Could Complete Blood Count Parameters and Non-fasting Cholesterol Profile Describe Inflammation and Oxidative Stress in Chronic Kidney Disease?

open access: yesIndonesian Biomedical Journal, 2018
BACKGROUND: Establishment of inexpensive clinical laboratory tests to evaluate inflammation and oxidative stress is urgently needed in the limited resources settings.
Ika Nindya Kadariswantiningsih   +10 more
doaj   +1 more source

Paradoxical mortality differential of HDL cholesterol

open access: yesAsian Journal of Medical Sciences, 2023
High-density lipoprotein (HDL) cholesterol has been known for ages to be cardio-protective due to its defensive action against genesis of atherosclerosis.
Jyotishman Mukhopadhyay   +2 more
doaj   +1 more source

Biophysical characterization of reactions associated with reverse cholesterol transport [PDF]

open access: yes, 2012
This thesis aimed at improving our understanding of reactions relevant in the reverse cholesterol transport (RCT). RCT facilitates cholesterol homeostasis and is the most important pathway involved in cardiovascular disease.
Zehender, Fabian
core   +1 more source

The High Density Lipoprotein Cholesterol Hypothesis Revisited

open access: yesIndonesian Biomedical Journal, 2018
BACKGROUND: The strong inverse association of plasma levels of high-density lipoprotein cholesterol (HDL-C) with coronary heart disease (CHD) found in human epidemiological studies led to the development of the ‘HDL-C hypothesis’, which posits that ...
Anna Meiliana   +2 more
doaj   +1 more source

Apolipoprotein M promotes cholesterol uptake and efflux from mouse macrophages

open access: yesFEBS Open Bio, 2021
Apolipoprotein M (ApoM) exhibits various anti‐atherosclerotic functions as a component of high‐density lipoprotein (HDL) particles. Scavenger receptor class B type I (SR‐BI) is a classic HDL receptor that mediates selective cholesterol uptake and ...
Shuang Yao   +6 more
doaj   +1 more source

Large-Scale Candidate Gene Analysis of HDL Particle Features

open access: yes, 2011
Background: HDL cholesterol (HDL-C) is an established marker of cardiovascular risk with significant genetic determination. However, HDL particles are not homogenous, and refined HDL phenotyping may improve insight into regulation of HDL metabolism.
Burton Paul R.   +125 more
core   +1 more source

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