Results 171 to 180 of about 260,746 (260)

Long‐Term Blood Pressure Variability, Hippocampal Subfield Volume and Cognitive Decline: A Population‐Based Prospective MRI Study

open access: yesJournal of Magnetic Resonance Imaging, EarlyView.
ABSTRACT Background Long‐term blood pressure variability (BPV) is associated with cognitive decline, yet the underlying mechanisms have not been fully elucidated. Purpose To investigate the associations between long‐term BPV and hippocampal subfield volume and cognitive function and to assess the mediation effect of hippocampal subfield volume.
Fei Li   +17 more
wiley   +1 more source

Association Between MRI‐Derived Right‐to‐Left Ventricular Volume Ratio and Regional Left Ventricular Myocardial Dysfunction in Patients With Pulmonary Arterial Hypertension

open access: yesJournal of Magnetic Resonance Imaging, EarlyView.
ABSTRACT Background Right ventricular (RV) to left ventricular (LV) end‐diastolic volume ratio (RV/LV) is a validated marker of RV dilation in pulmonary arterial hypertension (PAH), yet its impact on LV myocardial function and the underlying mediating pathway is incompletely characterized.
Han Fang   +11 more
wiley   +1 more source

Non‐linear association between tooth loss and cardiovascular diseases among middle‐aged adults

open access: yesJournal of Periodontology, EarlyView.
Abstract Background Although positive associations between fewer remaining teeth and an increased risk of various systemic diseases have been reported, the precise dose‐response relationship has not been fully clarified. This study aimed to evaluate the non‐linearity of the dose‐response association between the number of lost teeth and the risk of ...
Taro Kusama   +7 more
wiley   +1 more source

Severity of periodontitis and risk of ischemic stroke: A systematic review and meta‐analysis

open access: yesJournal of Periodontology, EarlyView.
Abstract Background Periodontitis is a prevalent chronic inflammatory disease with a systemic inflammatory burden and is implicated with vascular pathology. This systematic review and meta‐analysis evaluates the association between varying severities of periodontitis and ischemic stroke with various diagnostic criteria.
Steven Sitt   +2 more
wiley   +1 more source

Hypertransaminasemia in hospitalized children: Insights from a national multicenter study by the Italian Society of Pediatric Gastroenterology, Hepatology, and Nutrition

open access: yesJournal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives Hypertransaminasemia is a frequent finding in hospitalized children with common pediatric illnesses, often considered a transitory phenomenon associated with systemic inflammation/injury. This study aims to assess the prevalence and causes of incidentally detected hypertransaminasemia in children admitted to general pediatric units ...
Angelo Di Giorgio   +21 more
wiley   +1 more source

Tirzepatide use in adolescents with metabolic dysfunction‐associated steatotic liver disease (MASLD): A case series

open access: yesJPGN Reports, EarlyView.
Abstract Pediatric obesity and metabolic dysfunction‐associated steatotic liver disease (MASLD) prevalence has risen markedly over the past decade. Due to transition delays and workforce shortages, pediatric specialists often manage patients into young adulthood, and thus familiarity with adult pharmacotherapies for MASLD is essential.
Brandon J. Perumpail   +2 more
wiley   +1 more source

Anticancer potential of berberine: Molecular pathways and current clinical trial perspectives

open access: yesJSFA reports, EarlyView.
Abstract Cancer is constantly rising mortality rates due to its late prognosis, poor management, and expensive treatment. Multi‐sectoral approaches for cancer management include hygienic practices, synthetic drug exploitation, radiation therapy, and diet modifications.
Muhammad Maaz   +10 more
wiley   +1 more source

Gymnema sylvestre: Bioactive constituents, health benefits, and emerging applications in nutraceuticals and functional foods

open access: yesJSFA reports, EarlyView.
Abstract Gymnema sylvestre (Retz.) R.Br. ex‐Schult., commonly known as “gurmar” or “sugar destroyer,” belongs to the Apocynaceae family and is traditionally used in Ayurveda for diabetes management. This review synthesizes ethnomedicinal evidence with contemporary pharmacological studies, to evaluate the therapeutic properties and mechanistic actions ...
Faiza Saeed   +5 more
wiley   +1 more source

Anti‐hypercholesterolemic effects of barley and its role in the management of metabolic disorders: A comprehensive review

open access: yesJSFA reports, EarlyView.
Abstract The dietary and lifestyle practices have predominantly compromised human health, which are influenced by modernization and industrialization. Hypercholesterolemia, caused by the consumption of fatty and fried foods and a sedentary lifestyle, is a major modifiable risk factor for cardiovascular disease and commonly coexists with obesity ...
Muhammad Usman Khalid   +8 more
wiley   +1 more source

Gastroprotective effects of Sapodilla fruit powder against ethanol‐induced gastric injury in Sprague–Dawley rats: In silico prediction and in vivo validation

open access: yesJSFA reports, EarlyView.
Abstract Background Gastrointestinal disorders are rapidly increasing worldwide due to the disturbance of mucosal defenses. Manilkara zapota possesses significant therapeutic attributes to improve individual well‐being. Objectives The current study was conducted to evaluate the antioxidant activity, phytochemical characterization, and in silico and in ...
Ayesha Siddiqa   +7 more
wiley   +1 more source

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