Results 1 to 10 of about 604,324 (300)
Cellular cholesterol efflux and cholesterol loading capacity of serum: effects of LDL-apheresis
Journal of Lipid Research, 2012 High LDL-cholesterol (LDL-C) characterizes familial hypercholesterolemia (FH) and familial combined hyperlipidemia (FCH). LDL-apheresis, used in these patients to reduce LDL-C levels, has been shown to also affect HDL levels and composition.
M.P. Adorni +9 more
doaj +2 more sources
Journal of Lipid Research, 1989 These studies were undertaken to examine the effect of aging on low density lipoprotein (LDL) metabolism in the male hamster. When the hamsters were maintained on a low-cholesterol, low-triglyceride diet, rates of LDL transport in the various tissues of ...
D K Spady, J M Dietschy
doaj +1 more source
Fenofibrate treatment increases human serum proprotein convertase subtilisin kexin type 9 levels
Journal of Lipid Research, 2010 Over the past several years, proprotein convertase subtilisin kexin type 9 (PCSK9) has gained significant attention as a key regulator of serum LDL-cholesterol (LDL-C) levels.
Jason S. Troutt +3 more
doaj +1 more source
Journal of Lipid Research, 1994 Using ion exchange high pressure liquid chromatography, total plasma low density lipoprotein (LDL) from 30 hypercholesterolemic and 10 normocholesterolemic cynomolgus monkeys was subfractionated into unmodified LDL (n-LDL) and more negatively charged LDL
H.N. Hodis +7 more
doaj +1 more source
Journal of Lipid Research, 1982 Subcellular localization of nonesterified cholesterol has been determined in normal human fibroblasts from cultures incubated with human low density lipoprotein (LDL).
H S Kruth +4 more
doaj +1 more source
Journal of Lipid Research, 1996 Effectiveness of a simultaneous inhibition of cholesterol absorption and synthesis, caused by sitostanol ester margarine and pravastatin, was studied to control mild hypercholesterolemia in men with non-insulin-dependent diabetes mellitus (NIDDM) (n = 8).
H Gylling, T A Miettinen
doaj +1 more source
Cardiovascular outcomes and LDL-cholesterol levels in EMPA-REG OUTCOME
Diabetes & Vascular Disease Research, 2020 Objective: It is well established that higher low-density lipoprotein (LDL)-cholesterol levels are associated with increased cardiovascular risk. We analyzed whether effects of empagliflozin on cardiovascular outcomes varied by different LDL-cholesterol ...
Gisle Langslet +6 more
doaj +1 more source
Quantitation of the in vitro free cholesterol exchange of human red cells and lipoproteins
Journal of Lipid Research, 1970 The exchange of free cholesterol in vitro between human red blood cells and low density lipoproteins (LDL) was quantified. The flux of sterol between LDL and red cells was relatively constant over a wide range of concentrations of free cholesterol in ...
STEVEN H. QUARFORDT, HELEN L. HILDERMAN
doaj +1 more source
Standardization of Apolipoprotein B, LDL‐Cholesterol, and Non‐HDL‐Cholesterol
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2023 Concern continues about whether the measurement of apolipoprotein B (apoB) is adequately standardized, and therefore, whether apoB should be applied widely in clinical care. This concern is misplaced.
John H. Contois +3 more
doaj +1 more source
LDL cholesterol and atherosclerosis: The evidence.
Clinica e investigacion en arteriosclerosis : publicacion oficial de la Sociedad Espanola de Arteriosclerosis, 2021 The lipid theory of atherosclerosis dates back more than a century. Despite this, some authors have questioned the relevance of hypercholesterolaemia in its development. Multiple experimental, epidemiological, and clinical evidence underpins this association.
Guijarro, C, Cosin-Sales, J
openaire +2 more sources