Results 31 to 40 of about 1,208,067 (297)

Association between low-density lipoprotein cholesterol and sudden cardiac arrest in people with diabetes mellitus

Cardiovascular Diabetology, 2023
Background Dyslipidemia measured as low-density lipoprotein (LDL)-cholesterol is an established risk factor of cardiovascular disease, which is more pronounced in diabetes population.
Yun Gi Kim, Joo Hee Jeong, Kyung-Do Han, Seung-Young Roh, Kyongjin Min, Hyoung Seok Lee, Yun Young Choi, Jaemin Shim, Jong-Il Choi, Young-Hoon Kim   +9 more
doaj   +1 more source

Reduction of circulating cholesterol and apolipoprotein levels during sepsis [PDF]

, 1999
Sepsis with multiple organ failure is frequently associated with a substantial decrease of cholesterol levels. This decrease of cholesterol is strongly associated with mortality suggesting a direct relation between inflammatory conditions and altered ...
Peter Fraunberger, Karl Werdan, Werdan, Karl, Walli, Autar K., Autar K. Walli, Dietrich Seidel, Seidel, Dietrich, Steffen Schaefer, Fraunberger, Peter, Schaefer, Steffen   +9 more
core   +1 more source

Thyroid markers and body composition predict LDL-cholesterol change in lean healthy women on a ketogenic diet: experimental support for the lipid energy model [PDF]

, 2023
Introduction: There is a large heterogeneity in LDL-cholesterol change among individuals adopting ketogenic diets. Interestingly, lean metabolically healthy individuals seem to be particularly susceptible, with an inverse association between body mass ...
Cooper, Isabella D., Sanchez-Pizarro, Claudio, Feldman, David, Edwards, Kurtis, Petagine, Lucy, Norwitz, Nicholas G., Soto-Mota, Adrian, Elliot, Bradley T., Kyriakidou, Yvoni   +8 more
core   +1 more source

Cholesterol delivered to macrophages by oxidized low density lipoprotein is sequestered in lysosomes and fails to efflux normally

Journal of Lipid Research, 2000
Oxidized low density lipoprotein (LDL) has been found to exhibit numerous potentially atherogenic properties, including transformation of macrophages to foam cells.
Baljinder S. Dhaliwal, Urs P. Steinbrecher   +1 more
doaj   +1 more source

LDL particle size and LDL and HDL cholesterol changes with dietary fat and cholesterol in healthy subjects

Journal of Lipid Research, 1998
We have conducted a dietary trial in 54 men and 51 women with a wide range of fasting cholesterol values to examine the use of low density lipoprotein (LDL) particle size to predict the lipoprotein response to dietary fat and cholesterol.
Peter M. Clifton, Manny Noakes, Paul J. Nestel   +2 more
doaj   +1 more source

Efficacy and Safety of Alirocumab as Add-on Therapy in High–Cardiovascular-Risk Patients With Hypercholesterolemia Not Adequately Controlled With Atorvastatin (20 or 40 mg) or Rosuvastatin (10 or 20 mg)::Design and Rationale of the ODYSSEY OPTIONS Studies [PDF]

, 2014
The phase 3 ODYSSEY OPTIONS studies (OPTIONS I, NCT01730040; OPTIONS II, NCT01730053) are multicenter, multinational, randomized, double-blind, active-comparator, 24-week studies evaluating the efficacy and safety of alirocumab, a fully human monoclonal ...
Peter H. Jones, Robinson, Jennifer G., Hanotin, Corinne, Du, Yunling, Jones, Peter H., Harold E. Bays, Corinne Hanotin, Yunling Du, Colhoun, Helen M., Donahue, Stephen, Jennifer G. Robinson, Helen M. Colhoun, Stephen Donahue, Bays, Harold E.   +13 more
core   +1 more source

Decrease of LDL Cholesterol Through The Increase of HDL Cholesterol by Administering Garcinia mangostana L. Peel Extract in White Mice

Folia Medica Indonesiana, 2021
Highlight: • Ethanol extract of Garcinia mangostana L. peel reduce malondialdehyde. • Garcinia mangostana L. peel extract can increase non-radical products which impact in decreasing LDL cholesterol and increasing HDL cholesterol.
Hasyim As'ari
doaj   +1 more source

A Comparison of Two LDL Cholesterol Targets after Ischemic Stroke.

New England Journal of Medicine, 2019
BACKGROUND The use of intensive lipid-lowering therapy by means of statin medications is recommended after transient ischemic attack (TIA) and ischemic stroke of atherosclerotic origin.
P. Amarenco, Jong S. Kim, J. Labreuche, Hugo Charles, J. Abtan, Y. Béjot, L. Cabrejo, J. Cha, G. Ducrocq, M. Giroud, C. Guidoux, Cristina Hobeanu, Yong-Jae Kim, B. Lapergue, P. Lavallée, Byung-Chul Lee, K. Lee, D. Leys, M. Mahagne, E. Meseguer, N. Nighoghossian, F. Pico, Y. Samson, I. Sibon, P. Steg, S. Sung, P. Touboul, E. Touzé, O. Varenne, E. Vicaut, Nessima Yelles, E. Bruckert   +31 more
semanticscholar   +1 more source

Effect of a high intake of conjugated linoleic acid on lipoprotein levels in healthy human subjects [PDF]

, 2010
Background -Trans fatty acids are produced either by industrial hydrogenation or by biohydrogenation in the rumens of cows and sheep. Industrial trans fatty acids lower high-density lipoprotein (HDL) cholesterol, raise low-density lipoprotein (LDL ...
Wanders Anne J., Siebelink, E., Brouwer, I.A.; id_orcid, Martijn B. Katan, Katan Martijn B., Martijn B Katan, Ingeborg A Brouwer, Brouwer, I.A., Els Siebelink, Anne J. W, Katan, M.B.; id_orcid, Katan, M.B., Anne J Wanders, Siebelink Els, Wanders, A.J., Ingeborg A. Brouwer, Brouwer Ingeborg A.   +16 more
core   +4 more sources

Cholesterol deposition in macrophages: foam cell formation mediated by cholesterol-enriched oxidized low density lipoprotein.

Journal of Lipid Research, 1997
Oxidized low density lipoprotein (LDL) is thought to mediate the transformation of macrophages to cholesterol-rich foam cells. Yet convincing evidence for this process is lacking in vitro.
P Greenspan, H Yu, F Mao, R L Gutman
doaj   +1 more source