Results 121 to 130 of about 763,562 (268)

Aberrant Cholesterol Metabolism Caused by Decreased Lecithin: Cholesterol Acyltransferase Promoted Hepatocarcinogenesis. [PDF]

J Hepatocell Carcinoma
Gao H, Peng X, Wen Y, Gou L, Xu Y, Qu X, Wu J, Xue B.   +7 more
europepmc   +1 more source

Oligopeptides/DNA Coacervate Droplets as Macromolecular Delivery Microcarriers

Advanced Science, EarlyView.
Oligopeptide–DNA coacervates formed via liquid–liquid phase separation serve as programmable carriers for macromolecular cargos, entering cells through lipid raft–associated pathways and subsequently undergoing enzyme triggered intracellular disassembly driven by DNA degradation processes, thereby enabling efficient, controlled, and spatially defined ...
Linyi Zhang, Chong Wang, Mengqi Han, Yi Yang, Teng Ma, Luoran Shang   +5 more
wiley   +1 more source

Low temperature rather than hypoxia drives cholesterol synthesis and oxygen consumption in plateau zokors. [PDF]

iScience
Hu Q, Wei L, An Z, Wang Y, Zhang T, Wei D.   +5 more
europepmc   +1 more source

A Microgel Platform Enables Site‐Specific Intestinal Delivery of Lactoferrin, Improving its Bioavailability for Targeted Alleviating Liver Injury and Colitis

Advanced Science, EarlyView.
This work first time reports an eco‐friendly desert plant food‐based polysaccharide ASKP microgels which have intestinal site‐specific release properties which can achieve small‐intestine or colon targeting capability via different cross‐linking chemistry.
Huiling Yan, Yixuan Li, Shanan Chen, Pengcheng Du, Kaiwen Wu, Hui Zhang, Kasper Hettinga, Lina Zhang, Gergely Toldi, Fazheng Ren, Yuan Li   +10 more
wiley   +1 more source

Dietary fiber intake and gallstones: The mediating role of serum lipids. [PDF]

J Int Med Res
Jiang W, Wang F, Lin Y, Luo X, Zheng Y, Yan J, Yang W, Hu Z.   +7 more
europepmc   +1 more source

Ferritinophagy Rewires Carnitine‐Dependent Lipid Metabolism to Inhibit PRRSV and IAV Replication

Advanced Science, EarlyView.
NCOA4‐mediated ferritinophagy reprograms carnitine metabolism by disrupting Fe‐S cluster biogenesis, thereby establishing an iron‐lipid axis that suppresses various viruses, including PRRSV and IAV. However, viruses counteract this mechanism by degrading NCOA4.
Kaifeng Guan, Chenyang Yuan, Zekun Meng, Yanan Wang, Xueying Zhai, Chunjie Huang, Xiang Zhou, Gaiping Zhang   +7 more
wiley   +1 more source

Cholesterol and Cholesterol-Derived Molecules Differentially Modulate Neuronal Kv7.2/7.3 Channels. [PDF]

Arch Pharm (Weinheim)
Karabatak E, Nematswerani R, Meiritz V, Rychlik N, Seebohm G, Glorius F, Budde T.   +6 more
europepmc   +1 more source

THE ROLE OF LYMPH CHOLESTEROL IN THE REGULATION OF ENDOGENOUS CHOLESTEROL AND CHOLESTEROL ESTER SYNTHESIS

Journal of Biological Chemistry, 1958
L, SWELL, E C, TROUT, H, FIELD, C R, TREADWELL   +3 more
openaire   +2 more sources

Targeting PLD3 Reverses the Immunosuppressive Niche by Reprogramming Tumor‐Associated Macrophages and Potentiates Antitumor Immunity

Advanced Science, EarlyView.
PLD3 activates the lysosomal‐AKT‐NF‐κB axis to drive cellular senescence in macrophages, establishing an immunosuppressive TME by limiting the infiltration of cytotoxic T, NK, and NKT cells, which confers resistance to anti‐PD‐1 therapy. Abrine inhibits PLD3 expression, restoring antitumor immunity and synergizing with anti‐PD‐1 treatment.
Xingtu Qin, Qiong Li, Xuemei Xu, Yuhan Wu, Yin Zhu, Jieqiong Wu, Yuan Fang, Qiubei Chen, Shuyang Wang, Jiang Yu, Yaping Ye, Hongli Jiao   +11 more
wiley   +1 more source

Personalized polygenic profiling based on the genetic architecture of lipid metabolism in the Russian population. [PDF]

Front Cardiovasc Med
Mamchur A, Bruttan M, Daniel V, Kashtanova D, Zelenova E, Dzhumaniiazova I, Ivanov M, Matkava L, Blinova O, Mitrofanov S, Golubnikova L, Kumar N, Maralova E, Shingaliev A, Ezhov M, Meshkov A, Chubykina U, Pogorelova O, Tripoten M, Balahonova T, Viskova A, Komarova M, Gurtsiev T, Gomyranova N, Vorobeva Y, Hotuleva A, Kolyaskina M, Yudin V, Makarov V, Keskinov A, Kuzmina L, Boytsov S, Yudin S, Skvortsova V.   +33 more
europepmc   +1 more source