Results 121 to 130 of about 1,540,114 (361)

Serum cholesterol. Doing the right thing. [PDF]

open access: bronze, 1993
Jeremiah Stamler   +9 more
openalex   +1 more source

Biomimetic Copper‐Doped Nano‐Aluminum Adjuvant Potentiates Therapy in Chemoresistant Acute Myeloid Leukemia

open access: yesAdvanced Healthcare Materials, EarlyView.
We developed a novel copper‐doped aluminum nano‐adjuvant (CuNA) to overcome cytarabine resistance in acute myeloid leukemia (AML). CuNA effectively sensitizes drug‐resistant AML cells to cytarabine by inducing mitochondrial dysfunction and inhibiting HMGCR/GPX4 to amplify ferroptosis.
Chao He   +10 more
wiley   +1 more source

Small Extracellular Vesicles from Neural Cells: Physiological and Pathological Roles, and Potential in Neurodegenerative Therapy

open access: yesAdvanced Healthcare Materials, EarlyView.
Neural cell–derived small extracellular vesicles (sEVs) are emerging as pivotal mediators in neurodegenerative diseases, exerting both pathogenic and therapeutic functions. This review synthesizes current evidence on how sEVs from distinct neural cell types regulate neurodegeneration, neuroprotection, biomarker discovery, and targeted drug delivery ...
Muhammad Waqas Salim   +4 more
wiley   +1 more source

Red blood cell lipid distribution in the pathophysiology and laboratory evaluation of chorea-acanthocytosis and McLeod syndrome patients

open access: yesFrontiers in Physiology
The core neuroacanthocytosis syndromes, i.e., chorea-acanthocytosis/VPS13A disease (ChAc) and McLeod syndrome/XK disease (MLS), are respectively due to mutations in VPS13A and XK genes and share similar manifestations including the formation of ...
Anne-Sophie Cloos   +16 more
doaj   +1 more source

QuickStats: Trends in Mean Total Cholesterol Among Adults Aged 20-74 Years, by Age Group—United States, 1960-1962 to 1999-2002* [PDF]

open access: bronze, 2006
Cdc   +10 more
openalex   +1 more source

A Potential Long-Acting LDL-Cholesterol–Lowering PCSK9 Monoclonal Antibody

open access: gold, 2021
Yimin Cui   +9 more
openalex   +1 more source

Mapping the Cerebral Organoid Landscape: A Systematic Review of Preclinical 3D Models in Neuroscience

open access: yesAdvanced Healthcare Materials, EarlyView.
Cerebral organoids are transforming brain research, yet the field remains fragmented. This comprehensive systematic review maps 738 studies published between 2014 and 2024 to uncover trends, gaps, and opportunities across neuroscience. Introducing OrganoidMap—an interactive, open‐access platform to explore and compare models—this work enables ...
Anna Wolfram   +10 more
wiley   +1 more source

The Influence of Lipid Electric Charge on the Binding of Aβ(1–42) Amyloid Peptide to Bilayers in the Liquid-Ordered State

open access: yesBiomolecules
The amyloidogenic Aβ peptides are widely considered as a pathogenic agent in Alzheimer’s disease. Aβ(1-42) would form aggregates of amyloid fibrils on the neuron plasma membranes, thus perturbing neuronal functionality.
Hasna Ahyayauch   +3 more
doaj   +1 more source

Classification and Prediction of Low-Density Lipoprotein Cholesterol LDL-C in The Palestinian Patients Using Machine Learning Techniques

open access: bronze, 2021
Sanad Malaysha   +89 more
openalex   +1 more source

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