Results 101 to 110 of about 763,562 (268)

Gut Microbiota, Immunity, and Metabolism in the Progression From Chronic Liver Disease to Hepatocellular Carcinoma

Advanced Science, EarlyView.
This review explains how chronic liver injury progresses toward hepatocellular carcinoma through interconnected changes in gut microbes, metabolism, immunity, fibrosis, and diet. It highlights microbial metabolites, bile‐acid signaling, immune dysfunction, and nutritional or microbiome‐based interventions as opportunities to identify risk earlier ...
Yi Hu, Caiyan Lin, Lijie Zhang, Xue Jiang, Huawen Li, Yangzhe Wu   +5 more
wiley   +1 more source

Synchronization of oestrus in different sheep breeds by progesterone+ecg and investigation of cholesterol and progesterone levels [PDF]

Eurasian Journal of Veterinary Sciences
In this study, florogestone acetate+eCG were administered in different sheep breeds to synchronize oestrus in breeding season. Reproductive parameters, cholesterol and progesterone levels of pregnant animals were also investigated. Fifty-nine animals (15
Mehmet Uçar, Mustafa Gündoğan, Mehmet Özdemir, Mustafa Tekerli, Abdullah Eryavuz, Erdal Saban, Erhan Özenç   +6 more
doaj  

Optimized Ex Vivo Human Liver Slice Culture Maintains Extended Viability and Function for Hepatotoxicity Testing

Advanced Science, EarlyView.
An optimized ex vivo human liver slice culture system preserves tissue architecture, hepatocyte function, and immune‐stromal complexity for at least five days. By refining slice thickness, oxygenation, air‐liquid interface, and extracellular matrix support, the platform enables human‐relevant hepatotoxicity testing and mechanistic studies, offering a ...
Huiche Feng, Cinzia Esposito, Andrej Benjak, Matthias S. Matter, Miriam Cieri, Camilla De Carlo, Philipp Sedlaczek, Fabian Haak, Mattia Marinucci, Gabriel Fridolin Hess, Otto Kollmar, Mairene Coto‐Llerena, Luca Di Tommaso, Visar Vela, Lukas Bubendorf, Luigi M. Terracciano, Charlotte K. Y. Ng, Salvatore Piscuoglio   +17 more
wiley   +1 more source

Effects of zinc supplementation on some lipid parameters of plasma and erythrocyte membrane in angora coats [PDF]

Eurasian Journal of Veterinary Sciences
In the study, healthy and adult, 12 Angora goats were used. The animals were divided equally into two groups . Group 1 (Control) and Group 2 (Zn Group) were fed ad libitum with a basal ration and the basal ration supplemented with 250 ppm Zn for 3 months.
Ercan Keskin, Zafer Durgun, Nurcan Dönmez, Ramazan Çöl, Hüdai İpek   +4 more
doaj  

THE MOLECULAR MICRODISTILLATION OF CHOLESTEROL AND CHOLESTEROL ESTERS

Journal of Biological Chemistry, 1949
A E, KOEHLER, E, HILL
openaire   +2 more sources

Lilrb4a Suppression Reprograms Microglia to Mitigate APOE4‐Associated Amyloid Plaques and Cerebral Amyloid Angiopathy in Association With a PPAR‐Linked Pro‐Clearance State

Advanced Science, EarlyView.
Targeting Lilrb4a in Apolipoprotein E4 (APOE4)‐associated Alzheimer's disease (AD) reprograms microglia toward a beneficial, phagocytic state. Genetic deletion or antisense inhibition of Lilrb4a suppresses p‐SHP2/NF‐κB/STAT1 signaling, restores PPAR‐linked lipid and energy metabolism, and reduces amyloid plaque burden and cerebral amyloid angiopathy ...
Changxu Nie, Ruixi Yang, Xiaotong Wang, Ping Jia, Xueqi Zhang, Yaqi Dai, Xue Bai, Sijia Duan, Yufeng Li, Peng Zheng, Xin Tian, Li Jiang, Chao Wang   +12 more
wiley   +1 more source

Atorvastatin blocks Sonic Hedgehog medulloblastoma progression through apoptosis

Учёные записки Казанского университета: Серия Естественные науки, 2017
Aberrant activation of Sonic Hedgehog signaling transduction leads to formation of numerous malignancies, including medulloblastoma (MB) – the most common malignant pediatric tumor.
R.E. Gordon, Z.I. Abramova
doaj  

A Molecular Engineering Strategy to Fine‐Tune Phototoxicity of AIE Probes for Super‐Resolution Imaging of Mitochondrial Cristae Dynamics

Advanced Science, EarlyView.
Regulation of molecular packing, phototoxicity, and ROS output of AIE photosensitizers is achieved through carboxylation and alkyl‐chain‐length tuning. The probe designed via this strategy enables super‐resolution visualization of inner‐mitochondrial‐membrane cristae dynamics under controlled oxidative stress, and fluorescence‐lifetime imaging of ...
Kongqi Chen, Mengjie Wang, Chuen Kam, Zhiming Wang, Qinrong Zhang, Sijie Chen   +5 more
wiley   +1 more source

Dietary cholesterol [PDF]

Nature, 1984
Katan, M.B., Beynen, A.C.
openaire   +2 more sources

Engineering Microbial Particles for Next‐Generation Biomedical Platforms

Advanced Science, EarlyView.
Microbe‐derived particles (MDPs), which include extracellular vesicles, outer membrane vesicles, inclusion bodies, polysaccharide particles, and virus‐like particles, represent a rapidly expanding category of bioinspired nanomaterials. With their natural origin, intrinsic biocompatibility, and highly programmable functionality, MDPs serve as a ...
Yuting Li, Yunjie Lu, Ziyan Huang, Jianjiang Chen, Yanbin Liu, Lei Qin, Chao Wang, Yumin Wu   +7 more
wiley   +1 more source