Impact of Remnant Cholesterol on the Risk for End-Stage Renal Disease in Type 2 Diabetes Mellitus: A Nationwide Population-Based Cohort Study (Diabetes Metab J 2025;49:1106-15). [PDF]
Hong JH.
europepmc +2 more sources
Rethinking Statin Dosage in Coronary Disease. [PDF]
Dimmitt SB +3 more
europepmc +1 more source
Role of non-HDL-cholesterol in evaluation of dyslipidemia in preeclampsia
R Reena +3 more
openalex +1 more source
Sabotaged Integral HSC Heterogeneity Underlies Essential Thrombocythemia Development
Single‐cell RNA sequencing (scRNA‐seq) maps how distinct driver mutations remodel hematopoietic stem cell (HSC) programs across essential thrombocythemia (ET). Comparative analysis uncovers both shared and subtype‐specific molecular signatures, identifies a triple‐negative (TN)‐associated HSC population enriched with malignant traits, and reveals the ...
Jingyuan Tong +21 more
wiley +1 more source
Transmembrane movement and distribution of cholesterol in the membrane of vesicular stomatitis virus
Eric J. Patzer +4 more
openalex +1 more source
Neddylation Targets and Stabilizes NLRP3 to Augment Inflammasome‐Mediated Colitis and Mood Disorder
NLRP3 inflammasome contributes to colitis and mood disorder. This study demonstrates that neddylation targets NLRP3 at K287, which hinders its interaction with K48‐linked ubiquitination E3 Trim31 and thereby stabilizes it. Neddylation blockade in myeloid cells and microglia mitigates DSS‐induced colitis and psychological stress‐induced anxiety‐like ...
Wenbin Gai +13 more
wiley +1 more source
Effect of therapeutic plasma exchange on acquired hypocholesterolemia in patients with septic shock: a post hoc analysis of the two exchange trials. [PDF]
Pape T +12 more
europepmc +1 more source
In PCOS patients with hyperandrogenemia, decreased ferritin heavy chain 1 (FTH1) causes Fe2⁺ overload and ferroptosis in trophoblasts. Androgens induce FTH1 protein degradation via AR‐LAMP2A‐mediated chaperone‐mediated autophagy pathway, leading to placental development disruption and early pregnancy loss. Metformin mitigates androgen‐induced placental
Hanjing Zhou +10 more
wiley +1 more source
Lipid balance and chemoresistance in cancer cells. [PDF]
Kanemaru K, Nakamura Y.
europepmc +1 more source

