Results 181 to 190 of about 1,863,899 (386)

Effect of Nanoparticle Rigidity on the Interaction of Stromal Membrane Particles with Leukemia Cells

Advanced Healthcare Materials, EarlyView.
Cell membrane nanoparticles made with stromal cells are prepared and used to target leukemia cells. Deposition of the cell membrane onto rigid silica cores leads to increased uptake both in leukemia cell lines and primary cells from patients. These results show that nanoparticle rigidity affects the interaction between cell membrane nanoparticles and ...
Sander de Weerd, Xinyu Ma, Zahra Zohali, Lieve L. Oudejans, Emmanouil Kyrloglou, Marc. C. A. Stuart, Wouter H. Roos, Jan Jacob Schuringa, Anna Salvati   +8 more
wiley   +1 more source

Remnant Cholesterol, Not LDL Cholesterol, Is Associated With Incident Cardiovascular Disease.

Journal of the American College of Cardiology, 2020
O. Castañer, X. Pintó, I. Subirana, A. Amor, E. Ros, Á. Hernáez, M. Martínez-González, D. Corella, J. Salas‐Salvadó, R. Estruch, J. Lapetra, E. Gómez-Gracia, Á. Alonso-Gómez, M. Fiol, L. Serra-Majem, E. Corbella, D. Benaiges, J. Sorlí, M. Ruíz-Canela, N. Babio, L. T. Sierra, E. Ortega, M. Fitó   +22 more
semanticscholar   +1 more source

Heredity, Environment, and Serum Cholesterol [PDF]

, 1958
Louis E. Schaefer, D. Adlersberg, Arthur G. Steinberg   +2 more
openalex   +1 more source

Molecular Mechanisms of Extracellular Vesicle Biogenesis and Their Impact on the Design of Custom EVs

Advanced Healthcare Materials, EarlyView.
Extracellular vesicles (EVs) are pivotal mediators of intercellular communication and disease, yet the fundamental mechanisms controlling their biogenesis and cargo selection remain unclear. This limitation hinders their diagnostic utility and therapeutic development.
Luís Carvalho Ferraz, Paulo Pereira, João Vasco Ferreira   +2 more
wiley   +1 more source

Studies on the biosynthesis of cholesterol. 4. Degradation of rings C and D [PDF]

, 1957
J. W. Cornforth, Irene Youhotsky Gore, G. Popják   +2 more
openalex   +1 more source

Safety Evaluation of Repeated Application of Polymeric Microarray Patches in Miniature Pigs

Advanced Healthcare Materials, EarlyView.
This study demonstrates the safety of repeated application of three types of microarray patches (MAPs), hydrogelforming, dissolving, and implantable, over four weeks in miniature pigs. No adverse skin or systemic effects were observed, supporting the clinical potential of MAPs as safe and effective drug delivery platforms.
Qonita Kurnia Anjani, Aaron R. J. Hutton, Peter E. McKenna, Eneko Larrañeta, Ryan F. Donnelly   +4 more
wiley   +1 more source

Effect of Dietary Protein and Heated Fat on Serum Cholesterol and Beta-Lipoprotein Levels, and on the Incidence of Experimental Atherosclerosis in Chicks [PDF]

, 1958
T Nishida, Fumio Takenaka, F. A. Kummerow   +2 more
openalex   +1 more source

Imiquimod‐Loaded Phospholipid‐Free Small Unilamellar Vesicles Activate the Tumor Immune Microenvironment to Treat Liver Cancer and Liver Metastases

Advanced Healthcare Materials, EarlyView.
Imiquimod‐loaded nanoparticles (PFSUV‐IMQ) are found to decrease liver metastasis and liver tumor burden when administered intravenously. Flow cytometry, RNA‐seq and various experiments show that the anti‐tumor response is immune‐mediated by activating dendritic cells resulting in increased CD8 T cell infiltration and activity.
Vanessa Chan, Hsin‐Mei Lee, Haruka Takata, Sheng‐Liang Cheng, Yu‐Ting Yen, Lisa Pfeifer, Luke Rushton, Po‐Han Chao, Feng Zhao, Chun Yat Ong, Nojoud Al‐Fayez, Tatsuhiro Ishida, Yunching Chen, Shyh‐Dar Li   +13 more
wiley   +1 more source

OBSERVATIONS CONCERNING THE PRODUCTION AND EXCRETION OF CHOLESTEROL IN MAMMALS

, 1951
Sanford O. Byers, Meyer Friedman, Fred Michaelis   +2 more
openalex   +1 more source

The Effect of Vegetable Fat Ingestion on Human Serum Cholesterol Concentration [PDF]

, 1951
Eugene A. Hildreth, Sherman M. Mellinkoff, G. W. Scott Blair, D. M. HILDRETH   +3 more
openalex   +1 more source