Results 181 to 190 of about 1,523,799 (296)

Hepatocyte‐Derived Extracellular Vesicles Deliver miR‐328‐3p to Trigger PP2A‐B56δ–Mediated p‐NLRP3S295‐Dependent Metaflammation in Macrophages upon Microcystin‐LR Exposure

Advanced Science, EarlyView.
Hepatocyte‐derived extracellular vesicles deliver miR‐328‐3p to trigger PP2A‐B56δ–mediated p‐NLRP3S295‐dependent metaflammation in macrophages upon microcystin‐LR exposure. 2‐DG, 2‐deoxy‐D‐glucose. B56δ, protein phosphatase 2A‐B56δ. ER, endoplasmic reticulum. iHD‐EV, inducible hepatocyte‐derived extracellular vesicles. IP3R, inositol 1,4,5‐triphosphate
Jia‐Shen Wu, Xin‐Yu Zhang, Xin‐Yu Ma, Yue‐Yue Wei, Lei‐Lei Wang, Ze‐Bang Du, Xiao‐Gang Xia, Lin Che, Dong‐Bei Guo, Han‐Ying Zheng, You‐Liang Yao, Wen‐Gang Li, Yu‐Chun Lin, Zhong‐Ning Lin   +13 more
wiley   +1 more source

The emerging role of cholesterol metabolism in gynecologic cancer development and therapy. [PDF]

Apoptosis
Liu H, Zhou Y, Zhang J, Miao L, Wu Q, Zhu H, Pan S, Zhu X.   +7 more
europepmc   +1 more source

Abnormal cholesterol–cholesteryl ester metabolism impairs mouse oocyte quality during ovarian aging [PDF]

Sainan Zhang, Bichun Guo, Junshun Fang, Shanshan Wang, Yicen Liu, Die Wu, Nannan Kang, Yang Zhang, Xin Zhen, Guijun Yan, Lijun Ding, Haixiang Sun, Chuanming Liu   +12 more
openalex   +1 more source

PD‐1 Inhibits CD4+ TRM‐Mediated cDC1 Mobilization via Suppressing JAML in Human NSCLC

Advanced Science, EarlyView.
CD4+ tissue‐resident memory T cells (TRMs) in non‐small cell lung cancer recruit conventional type 1 dendritic cells via XCL1‐XCR1 signaling, orchestrating antitumor immunity. The costimulatory molecule JAML is essential for this process. PD‐1 blockade restores JAML expression and cDC1 mobilization, while JAML agonists synergize with anti‐PD‐1 therapy,
Zheyu Shao, Qinyuan Liu, Zhongwei Xin, Zhiyao Zhou, Mingjie Lin, Di Chen, Zhixing Hao, Yongyuan Chen, Wenxuan Wu, Shuyang Zhang, Xiaoke Chen, Xia Xu, Jinfan Li, Wei Lin, Yuhao Lu, Dang Wu, Pin Wu   +16 more
wiley   +1 more source

Association of triglyceride and cholesterol with vestibular vertigo: Evidence from univariable and multivariable mendelian randomization and mediation analysis. [PDF]

Braz J Otorhinolaryngol
Mu Y, Lu Y, Fu W.
europepmc   +1 more source

Regulating Tumor Metabolic Reprogramming with Biomimetic Co‐Delivery of Simvastatin and Kynureninase for Immunotherapy

Advanced Science, EarlyView.
After the intravenous injection of biomimetic and pH/ROS‐responsive PTSK@CRM, the nanoparticles can be accumulated in tumors and release Sim and KYNase to inhibit the tumor growth, regulate the metabolism of cholesterol and Kyn, and reverse the immunosuppressive tumor microenvironment.
Jiaxin Yin, Shengcai Yang, Zengguang Liu, Songchen Zhao, Siyu Sun, Ziling Liu, Quanshun Li   +6 more
wiley   +1 more source

SLC25A1-Mediated Cholesterol Accumulation Promotes Endometriosis Progression by Enhancing Endometrial Stromal Cell Proliferation, Invasion, and M2 Macrophage Polarization. [PDF]

Int J Biol Sci
Yang P, Wang T, Miao Y, Liu W, Zhu Y, Sun J.   +5 more
europepmc   +1 more source

Effect of Elastase on Lipid Accumulation in Rabbit Aorta Fed on High-cholesterol Diet

, 1986
Shunichi MIJRANO, Ikuko Osawa, Yasuko Shiki, Tetsuto Kanzaki, Yoh ISHIKAWA, Toshio NISHIDE, Masaki Shinomiya, Nobuhiro Morisaki, Kohji Shirai, Yasushi Saitō, Akira Miyazaki, Yoshiaki Masuda, Yoshiaki Inagaki, Jun‐ichi Tamaru, Isao Iwasaki, Sho Yoshida   +15 more
openalex   +2 more sources

Cholesterol accumulation by suppression of SMT1 leads to dwarfism and improved drought tolerance in herbaceous plants [PDF]

, 2018
Miao Chen, Jingjing Chen, Na Luo, Rongda Qu, Zhenfei Guo, Shaoyun Lu   +5 more
openalex   +1 more source

Reduced LDL-Cholesterol and Reduced Total Cholesterol as Potential Indicators of Early Cancer in Male Treatment-Naïve Cancer Patients With Pre-cachexia and Cachexia [PDF]

, 2020
Hannes Zwickl, Klaus Hackner, Harald Köfeler, Eva-Christina Krzizek, Besnik Muqaku, Dietmar Pils, Hubert Scharnagl, Tora S. Solheim, Elisabeth Zwickl-Traxler, Martin Pecherstorfer   +9 more
openalex   +1 more source