Results 251 to 260 of about 1,523,799 (296)
Targeting Endothelial KDM5A to Attenuate Aging and Ameliorate Age‐Associated Metabolic Abnormalities
This study identifies endothelial KDM5A as a key regulator of aging. KDM5A deficiency accelerates aging by enhancing H3K4me3‐mediated FABP4 expression, disrupting fatty acid metabolism, and promoting multi‐organ senescence. KDM5A restoration or FABP4 inhibition reverses these adverse effects and extends lifespan, positioning the KDM5A/FABP4 axis as a ...
Rifeng Gao +21 more
wiley +1 more source
We designed a synthetic DNA origami needle‐like structure inspired by bacteriophages for targeted drug delivery. Functionalized with trastuzumab antibodies, cholesterol, and dyes, it selectively targets SKBR3 cancer cells. A glutathione‐triggered dye payload enables controlled release, and delivery is verified using confocal microscopy and live cell ...
Anirban Samanta +7 more
wiley +1 more source
Cholesterol-mediated inflammation activation in alveolar macrophages. [PDF]
Giambelluca S +2 more
europepmc +1 more source
Gli1+ adventitial stem cells (ASCs) have been thought to generate smooth muscle cells (SMCs) in atherosclerosis. Using a dual‐recombinase lineage tracing to exclude ectopic labeling, Wang et al. found that Gli1+ ASCs do not contribute to SMCs in atherosclerotic plaques.
Haixiao Wang +11 more
wiley +1 more source
Cholesterol Particle Interaction with the Surface of Blood Vessels
Raimondas Jasevičius
openalex +1 more source
The age‐associated disparity of nanocarrier biodistribution limits the nanotherapeutics of childhood solid tumors. This study developed an ultrasound‐activated liposomal prodrug (CSCPTL) to overcome the age‐associated disparity of off‐target distribution.
Danfei Chen +8 more
wiley +1 more source
Cholesterol Awareness in the Transgender Population: A Comparison With Cisgender Cohort. [PDF]
Sharma A +3 more
europepmc +1 more source
Cholesterol modulation of photoreceptor function in bovine retinal rod outer segments.
Kathleen Boesze‐Battaglia +1 more
openalex +1 more source

