Results 281 to 290 of about 1,802,229 (363)
Advanced Science, EarlyView.PANEs are specifically designed to enhance the brain delivery efficiency of circDYM compared to commercialized lipid nanoparticles (LNPs). Intranasal administration of PANE‐circDYM effectively alleviated LPS‐induced depressive‐like behaviors by mitigating neuroinflammation and promoting neuroplasticity.
Feng Gao +11 more
wiley +1 more source
Epigenetic Modifications in Alternative Splicing of LDLR pre-mRNA on Hypercholesterolemia Following Aerobic Exercise Training. [PDF]
Int J Mol SciZhao J, Yan P, Pang Y, Dong Y, Shi X.
europepmc +1 more source
A Century of Cholesterol and Coronaries: From Plaques to Genes to Statins
Cell, 2015 J. Goldstein, Michael S. Brown
semanticscholar +1 more source
Advanced Science, EarlyView.TRIM25‐mediated ubiquitination of INSIG1 serves as a key driver of lipid metabolism dysregulation in MASH progression. It identifies a novel small‐molecule inhibitor, C27H26N2O4S, which effectively inhibits TRIM25 activity, reducing lipid accumulation and inflammation.
Hao Zhang +8 more
wiley +1 more source
Ubiquitination in lipid metabolism reprogramming: implications for pediatric solid tumors. [PDF]
Front ImmunolZhang W +8 more
europepmc +1 more source
Advanced Science, EarlyView.Overview of the regulation of intrinsic and extrinsic signals during neurodevelopment. Intrinsic genetic signals from NSCs, in conjunction with cues from microglia and blood vessels, collaboratively regulate the proliferation of NSCs, their fate determination, synaptogenesis, synaptic pruning, neuronal survival, and death, as well as communication ...
Yanyan Wang +4 more
wiley +1 more source
Quantitative proteomic analysis of the protective effect exerted by alliin on ox-LDL-injured HUVECs. [PDF]
Sci RepTang YY, Lv.
europepmc +1 more source
A REVISION OF THE SCHOENHEIMER-SPERRY METHOD FOR CHOLESTEROL DETERMINATION
, 1950 Warren M. Sperry, Merrill Webb
openalex +1 more source
Advanced Science, EarlyView.Aided by FABP5, abnormally elevated asprosin in hepatocytes enters the nucleus, targets and inhibits PPARα binding to the CPT1A promoter, thereby suppressing FAO. Circulating asprosin exacerbates insulin resistance, collectively driving MASLD progression.
Yuan‐Yuan Yu +13 more
wiley +1 more source
The non-linear association between remnant cholesterol/high-density lipoprotein cholesterol ratio and diabetic retinopathy: a cross-sectional study in type 2 diabetic patients. [PDF]
Diabetol Metab SyndrWei C +8 more
europepmc +1 more source