Results 21 to 30 of about 2,069,563 (390)
Advances in Laboratory Medicine, 2023 Cardiovascular diseases (CVD) continue to be the main cause of death in our country. Adequate control of lipid metabolism disorders is a key challenge in cardiovascular prevention that is far from being achieved in real clinical practice.
Arrobas Velilla Teresa +18 more
doaj +1 more source
Genetic obesity increases pancreatic expression of mitochondrial proteins which regulate cholesterol efflux in BRIN-BD11 insulinoma cells [PDF]
, 2019 Pancreatic β-cells are sensitive to fluctuations in cholesterol content, which can damage the insulin secretion pathway, contributing to the aetiology of type 2 diabetes mellitus.
Caridis, Anna Maria +4 more
core +1 more source
Pregnancy and the Biliary Tract
Canadian Journal of Gastroenterology, 2000 Pregnancy induces many physiological changes, some of which may have pathological results. In population studies, gallstones were found in 6.5% to 8.4% of nulliparous women, and in 18.4% to 19.3% of women with two to three or more pregnancies.
Tuvia Gilat, Fred Konikoff
doaj +1 more source
Cholesterol nucleation time in gallbladder bile of patients with solitary or multiple cholesterol gallstones [PDF]
, 1992 Patients with multiple cholesterol gallbladder stones have been found to be at a higher risk for the recurrence of gallstones after successful nonsurgical treatment than those with a solitary stone.
Abell +27 more
core +1 more source
Dendrogenin A drives LXR to trigger lethal autophagy in cancers
Nature Communications, 2017 Dendrogenin A, cholesterol metabolite, has tumor suppressive properties but the mechanisms are unknown. Here the authors show that Dendrogenin A can induce autophagy-mediated cell death in both melanoma and acute myeloid leukaemia.
Gregory Segala +34 more
doaj +1 more source
Molecules, 2019 Umbelliprenin has recently been shown to have great potential as a skin whitening agent. Wishing to investigate the same effect in plant species known to biosynthesize this coumarin, three plants belonging to the Apiaceae family, namely Anethum ...
Vito Alessandro Taddeo +9 more
doaj +1 more source
Journal of Extracellular Vesicles, 2023 Macrophages play major roles in the pathophysiology of various neurological disorders, being involved in seemingly opposing processes such as lesion progression and resolution.
Sam Vanherle +17 more
doaj +1 more source
, 1968 Acute cholesterol depletion is generally associated with decreased or abolished T cell signalling but it can also cause T cell activation. This anomaly has been addressed in Jurkat T cells using progressive cholesterol depletion with methyl-beta ...
Adler, Jeremy +3 more
core +2 more sources
Advances in Orthopedics, 2015 In 6 patients with familial thrombophilia (5 Factor V (FV) Leiden heterozygotes, 1 with resistance to activated protein C (RAPC)), we prospectively assessed whether continuous longterm (4–16 years) anticoagulation would prevent progression of idiopathic ...
Charles J. Glueck +3 more
doaj +1 more source
Biliary cholesterol crystallization characterized by single-crystal cryogenic electron diffraction
Journal of Lipid Research, 2005 Cholesterol crystals are the building blocks of cholesterol gallstones. The exact structure of early-forming crystals is still controversial. We combined cryogenic-temperature transmission electron microscopy with cryogenic-temperature electron ...
Daphne Weihs +6 more
doaj +1 more source