Results 41 to 50 of about 1,060,215 (310)

Rats with high aerobic capacity display enhanced transcriptional adaptability and upregulation of bile acid metabolism in response to an acute high‐fat diet

Physiological Reports, 2022
Rats selectively bred for the high intrinsic aerobic capacity runner (HCR) or low aerobic capacity runner (LCR) show pronounced differences in susceptibility for high‐fat/high sucrose (HFHS) diet‐induced hepatic steatosis and insulin resistance ...
Harrison D. Stierwalt, E. Matthew Morris, Adrianna Maurer, Udayan Apte, Kathryn Phillips, Tiangang Li, Grace M. E. Meers, Lauren G. Koch, Steven L. Britton, Greg Graf, R. Scott Rector, Kelly Mercer, Kartik Shankar, John P. Thyfault   +13 more
doaj   +1 more source

Lipid composition and cholesterol nucleation time in gallbladder bile of patients with cholesterol gallstones under choleretic treatment with febuprol [PDF]

, 1988
The effect of a new potent choleretic drug (Febuprol) on lipid composition and cholesterol nucleation time in gallbladder bile was studied in 8 patients with cholesterol gallstones.
Paumgartner, Gustav, Pratschke, Ekkehard, Jüngst, Dieter, Brenner, Gerhard   +3 more
core   +1 more source

Vascular robustness: The missing parameter in cardiovascular risk prediction

Preventive Medicine Reports, 2018
Undetected high risk for premature death of cardiovascular disease (CVD) among individuals with low-to-moderate risk factor scores is an acknowledged obstacle to CVD prevention.
Lutz E. Kraushaar, Alexander Dressel, Alexander Maßmann   +2 more
doaj   +1 more source

Fibronectin in human gallbladder bile: cholesterol pronucleating and/or mucin "link" protein? [PDF]

, 1994
Some biliary proteins (pronucleators) seem to be essential factors for cholesterol crystal formation and crystal growth in bile. A recent study suggests that fibronectin is such a pronucleator in bile.
Ritter, Christoph von, Lange, Volker, Del Pozo, Reginals, Paumgartner, Gustav, V. Lange, J. F. Miquel, R. Del Pozo, G. Paumgartner, Jüngst, Dieter, Miquel, Juan Francisco, C. Von Ritter, D. Jungst   +11 more
core   +1 more source

Liver-specific FGFR4 knockdown in mice on an HFD increases bile acid synthesis and improves hepatic steatosis

Journal of Lipid Research, 2023
Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver disease with increased risk in patients with metabolic syndrome. There are no FDA-approved treatments, but FXR agonists have shown promising results in clinical studies for NAFLD ...
Francois Moreau, Bruna Brasil Brunao, Xiang-Yu Liu, Frederic Tremblay, Kevin Fitzgerald, Julian Avila-Pacheco, Clary Clish, Ronald C. Kahn, Samir Softic   +8 more
doaj   +1 more source

Effects of ursodeoxycholic acid on synthesis of cholesterol and bile acids in healthy subjects [PDF]

, 2004
Background/Aims: Ursodeoxycholic acid ( UDCA) decreases biliary secretion of cholesterol and is therefore used for the dissolution of cholesterol gallstones.
Thiessen, K., Parhofer, K. G., Fischer, S., Sauter, G. H., Jungst, D., Jungst, C.   +5 more
core   +1 more source

The effect of oligomeric procyanidins on endothelial function and cholesterol homeostasis [PDF]

, 2012
PhDOligomeric procyanidins (OPC) are naturally occurring dietary substances, which studies suggest can protect against cardiovascular disease. To explore this further a double-blind randomised controlled crossover trial, EPICURE (Evaluation of high ...
Rull, Gurvinder Kaur
core   +4 more sources

Cholesterol oxides inhibit cholesterol esterification by lecithin: cholesterol acyl transferase

Brazilian Journal of Pharmaceutical Sciences, 2009
Cholesterol oxides are atherogenic and can affect the activity of diverse important enzymes for the lipidic metabolism. The effect of 7β-hydroxycholesterol, 7-ketocholesterol, 25-hydroxycholesterol, cholestan-3β,5α,6β-triol,5,6β ...
Eder de Carvalho Pincinato, Patricia Moriel, Dulcinéia Saes Parra Abdalla   +2 more
doaj   +1 more source

Effect of Rosuvastatin and Glibenclamide in Alone or in Combination on Glucose Homeostasis in Diabetic Male Albino Wistar Rats: An Observer-blinded Experimental Interventional Study

National Journal of Laboratory Medicine, 2023
Introduction: Metabolic Syndrome (MetS) is a complex of metabolic disorders which include obesity, insulin resistance, hyperglycaemia, hypertension along with dyslipidemia. It is not clear whether rosuvastatin is having role in new onset diabetes. Aim:
Suganya Ganesan, Balaji More, Selvalaxmi Gnansegaran, Isswarya Anandan, Nitya Selvaraj, Jayaram Mohanasundaram   +5 more
doaj   +1 more source

Reduction of circulating cholesterol and apolipoprotein levels during sepsis [PDF]

, 1999
Sepsis with multiple organ failure is frequently associated with a substantial decrease of cholesterol levels. This decrease of cholesterol is strongly associated with mortality suggesting a direct relation between inflammatory conditions and altered ...
Peter Fraunberger, Karl Werdan, Werdan, Karl, Walli, Autar K., Autar K. Walli, Dietrich Seidel, Seidel, Dietrich, Steffen Schaefer, Fraunberger, Peter, Schaefer, Steffen   +9 more
core   +1 more source