Results 41 to 50 of about 1,540,114 (361)
The accumulation and aggregation of the amyloid-β peptide (Aβ) in the brain are important contributing factors to Alzheimer's disease (AD). Consequently, blocking the generation of Aβ is a potentially important treatment strategy.
Robert L. Raffaï, Karl H. Weisgraber
doaj +1 more source
Introduction: Metabolic Syndrome (MetS) is a complex of metabolic disorders which include obesity, insulin resistance, hyperglycaemia, hypertension along with dyslipidemia. It is not clear whether rosuvastatin is having role in new onset diabetes. Aim:
Suganya Ganesan +5 more
doaj +1 more source
Fibronectin in human gallbladder bile: cholesterol pronucleating and/or mucin "link" protein? [PDF]
Some biliary proteins (pronucleators) seem to be essential factors for cholesterol crystal formation and crystal growth in bile. A recent study suggests that fibronectin is such a pronucleator in bile.
Del Pozo, Reginals +5 more
core +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Hepatic cholesterol metabolism in cholesterol gallstone disease
Hepatic cholesterol metabolism was examined in 27 Swedish patients with cholesterol gallstone disease and in 13 patients free of gallstones operated for roentgenographically suspect polyps in the gallbladder.
E Reihnér +3 more
doaj +1 more source
Investigating the Status of Healthy Nutrition Index, Fat, Cholesterol and Sodium Intake in Residents Over 19 Years of Age in Yasuj, Iran, in 2020 [PDF]
Background & aim: Unhealthy diet - as one of the main risk factors of non-communicable diseases and responsible for most chronic diseases and their mortality, which affects people's health regardless of age, gender and social cultural conditions.
JM Malekzadeh +2 more
doaj
A CYPome-wide study reveals new potential players in the pathogenesis of Parkinson’s disease
Genetic and environmental factors lead to the manifestation of Parkinson’s disease (PD) but related mechanisms are only rudimentarily understood. Cytochromes P450 (P450s) are involved in the biotransformation of toxic compounds and in many physiological ...
Philip Hartz +5 more
doaj +1 more source
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Nonpharmacological cholesterol-lowering approach: Managing cholesterol naturally
Cholesterol is a lipid molecule which is biosynthesized by all animal cells. Also, it is an essential structural component of cell membranes which is normally required for maintaining both fluidity and membrane structural integrity. Dyslipidemia is known
Lubna Mahmood
doaj +1 more source
Cholesterol and Malondialdehyde Contents of Broiler-Chicken Meat Supplemented with Indigofera Zolingeriana Top Leaf Meal [PDF]
This research aimed to increase functional value of broiler-chicken meat containing high antioxidant and low cholesterol through substitution of soybean meal (SBM) with Indigofera zollingeriana top leaf meal (ILM). The experiment used 160 day old broiler
Abdullah, L. (L) +2 more
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