Results 41 to 50 of about 2,069,563 (390)
Effects of ursodeoxycholic acid on synthesis of cholesterol and bile acids in healthy subjects [PDF]
, 2004 Background/Aims: Ursodeoxycholic acid ( UDCA) decreases biliary secretion of cholesterol and is therefore used for the dissolution of cholesterol gallstones.
Fischer, S. +5 more
core +1 more source
Journal of Lipid Research, 2023 Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver disease with increased risk in patients with metabolic syndrome. There are no FDA-approved treatments, but FXR agonists have shown promising results in clinical studies for NAFLD ...
Francois Moreau +8 more
doaj +1 more source
Metabolomic study of the LDL receptor null mouse fed a high-fat diet reveals profound perturbations in choline metabolism that are shared with ApoE null mice [PDF]
, 2010 Failure to express or expression of dysfunctional low-density lipoprotein receptors (LDLR) causes familial hypercholesterolemia in humans, a disease characterized by elevated blood cholesterol concentrations, xanthomas, and coronary heart disease ...
Benson, G. Martin +5 more
core +1 more source
Journal of Lipid Research, 2003 The accumulation and aggregation of the amyloid-β peptide (Aβ) in the brain are important contributing factors to Alzheimer's disease (AD). Consequently, blocking the generation of Aβ is a potentially important treatment strategy.
Robert L. Raffaï, Karl H. Weisgraber
doaj +1 more source
National Journal of Laboratory Medicine, 2023 Introduction: Metabolic Syndrome (MetS) is a complex of metabolic disorders which include obesity, insulin resistance, hyperglycaemia, hypertension along with dyslipidemia. It is not clear whether rosuvastatin is having role in new onset diabetes. Aim:
Suganya Ganesan +5 more
doaj +1 more source
Measurement of Total Cholesterol, HDL-Cholesterol, and LDL-Cholesterol
Clinics in Laboratory Medicine, 1989 Plasma concentrations of LDL and HDL are generally measured in terms of their cholesterol content. This requires the separation of the appropriate lipoprotein-containing fractions. The separation and measurement of each fraction are described.
openaire +2 more sources
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Polyphenol alkyl ester inhibits membrane cholesterol domain formation through an antioxidant mechanism based, in nonlinear fashion, on chain length [PDF]
, 2017 Under conditions of oxidative stress, cholesterol aggregates into discrete membrane bilayer domains that precipitate the formation of extracellular crystals, a hallmark feature of the advanced atheroma in cardiovascular disease.
Durand, Erwann +4 more
core +1 more source
Hepatic cholesterol metabolism in cholesterol gallstone disease
Journal of Lipid Research, 1991 Hepatic cholesterol metabolism was examined in 27 Swedish patients with cholesterol gallstone disease and in 13 patients free of gallstones operated for roentgenographically suspect polyps in the gallbladder.
E Reihnér +3 more
doaj +1 more source
Investigating the Status of Healthy Nutrition Index, Fat, Cholesterol and Sodium Intake in Residents Over 19 Years of Age in Yasuj, Iran, in 2020 [PDF]
Armaghane Danesh Bimonthly Journal, 2023 Background & aim: Unhealthy diet - as one of the main risk factors of non-communicable diseases and responsible for most chronic diseases and their mortality, which affects people's health regardless of age, gender and social cultural conditions.
JM Malekzadeh +2 more
doaj