Results 41 to 50 of about 1,802,229 (363)
Changes to cholesterol trafficking in macrophages by Leishmania parasites infection [PDF]
Leishmania spp. are protozoan parasites that are transmitted by sandfly vectors during blood sucking to vertebrate hosts and cause a spectrum of diseases called leishmaniases.
Anderson+67 more
core +2 more sources
Cholesterol oxides inhibit cholesterol esterification by lecithin: cholesterol acyl transferase
Cholesterol oxides are atherogenic and can affect the activity of diverse important enzymes for the lipidic metabolism. The effect of 7β-hydroxycholesterol, 7-ketocholesterol, 25-hydroxycholesterol, cholestan-3β,5α,6β-triol,5,6β ...
Eder de Carvalho Pincinato+2 more
doaj +1 more source
Bad cholesterol and good mood: exploring the link
It is a well-known fact that high cholesterol increases the risks of heart disease. Hence, physicians actively encourage cholesterol-lowering interventions using medications and lifestyle modifications.
Yashaswi Gupta
doaj +1 more source
Phase diagram of a ternary mixture of cholesterol and saturated and unsaturated lipids calculated from a microscopic model [PDF]
We employ a molecular model to study a ternary mixture of saturated lipid, with tails of sixteen carbons, a mono unsaturated lipid with tails of eighteen carbons, and cholesterol. The model, solved within mean-field theory, produces several forms of phase diagrams depending upon the relative strengths of interactions, but only one that shows the ...
arxiv +1 more source
BACKGROUND The effects of dietary fats on the risk of coronary artery disease (CAD) have traditionally been estimated from their effects on LDL cholesterol.
R. Mensink, P. Zock, A. Kester, M. Katan
semanticscholar +1 more source
Genetic obesity increases pancreatic expression of mitochondrial proteins which regulate cholesterol efflux in BRIN-BD11 insulinoma cells [PDF]
Pancreatic β-cells are sensitive to fluctuations in cholesterol content, which can damage the insulin secretion pathway, contributing to the aetiology of type 2 diabetes mellitus.
Caridis, Anna Maria+4 more
core +1 more source
Background Nutritional modulation remains central to the management of metabolic syndrome. Intervention with cinnamon in individuals with metabolic syndrome remains sparsely researched.
Sonal Gupta Jain+4 more
doaj +1 more source
The impact of a carbon nanotube on the cholesterol domain localized on a protein surface [PDF]
The influence of a single walled carbon nanotube on the structure of a cholesterol cluster (domain) developed over the surface of the endothelial protein 1LQV has been investigated using the classical molecular dynamics (MD) simulation technique. We have observed a substantial impact of carbon nanotube on the arrangement of the cholesterol domain.
arxiv +1 more source
How cholesterol stiffens unsaturated lipid membranes
Significance Cholesterol regulates critical cell functions, including lysis, viral budding, and antibiotic resistance, by modifying the bending rigidity of cell membranes; i.e., the ability of membranes to bend or withstand mechanical stresses.
Saptarshi Chakraborty+13 more
semanticscholar +1 more source
Raft-like domain formation in model lipid-cholesterol aggregation [PDF]
To understand mechanism of cell-membrane compartmentalization, we studied coarse-grained model systems consisting of lipid and cholesterol molecules. Cholesterol plays crucial role in lateral phase segregation in the bilayered lipid membrane to form cholesterol rich liquid ordered domains, termed as `rafts'.
arxiv