Results 71 to 80 of about 1,802,229 (363)
Sprouty2 loss‐induced IL6 drives castration‐resistant prostate cancer through scavenger receptor B1 [PDF]
, 2018 Metastatic castration‐resistant prostate cancer (mCRPC) is a lethal form of treatment‐resistant prostate cancer and poses significant therapeutic challenges.
Ahmad, Imran +16 more
core +2 more sources
FEBS Letters, EarlyView.B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro +2 more
wiley +1 more source
Frontiers in Pharmacology, 2018 N,N-dimethyl-3β-hydroxycholenamide (DMHCA) is an experimental pharmaceutical and a steroidal liver X receptor (LXR) agonist, which does not induce undesired hepatic lipogenesis.
Nicole El-Darzi +5 more
doaj +1 more source
A Two-Phase Model of Early Atherosclerotic Plaque Development with LDL Toxicity Effects [PDF]
arXiv, 2023 Atherosclerosis is a chronic inflammatory cardiovascular disease in which fatty plaque is built inside an artery wall. Early atherosclerotic plaque development is typically characterized by inflammatory tissues primarily consisting of foam cells and macrophages.
arxiv
Structure and Function of Sphingolipid- and Cholesterol-rich Membrane Rafts*
Journal of Biological Chemistry, 2000 It is well known that separate domains with different lipid compositions can exist in liposomes containing mixtures of different phospholipids. The question of whether cellular membranes contain similar lipid domains has intrigued workers for many years.
Deborah A. Brown, E. London
semanticscholar +1 more source
Molecular Oncology, EarlyView.Triacsin C inhibition of the acyl‐CoA synthetase long chain (ACSL) family decreases multiple myeloma cell survival, proliferation, mitochondrial respiration, and membrane potential. Made with Biorender.com. Multiple myeloma (MM) is an incurable cancer of plasma cells with a 5‐year survival rate of 59%.
Connor S. Murphy +12 more
wiley +1 more source
Is reverse cholesterol transport regulated by active cholesterol?
Journal of Lipid Research, 2023 This review considers the hypothesis that a small portion of plasma membrane cholesterol regulates reverse cholesterol transport in coordination with overall cellular homeostasis.
Theodore L. Steck, Yvonne Lange
doaj
Arquivo Brasileiro de Medicina Veterinária e Zootecnia, 2007 Avaliaram-se as concentrações plasmáticas de triglicérides, colesterol, aspartato transaminase (AST) e progesterona (P4) em vacas Nelore não lactantes com elevado escore corporal, superovuladas com diferentes protocolos.
A.F. Ramos +5 more
doaj +1 more source
Effect of cholesterol on the mechanical stability of gel-phase phospholipid bilayers studied by AFM force spectroscopy [PDF]
arXiv, 2023 The low sliding friction of articular cartilage in the major joints , which is crucial for its homeostasis and for joint health, has been attributed to lipid bilayers forming lubricious boundary layers at its surface. The robustness of such layers, and thus their lubrication efficiency at joint pressures, depends on the lipids forming them, including ...
arxiv
Differential Effects of Lipid-lowering Drugs in Modulating Morphology of Cholesterol Particles. [PDF]
, 2017 Treatment of dyslipidemia patients with lipid-lowering drugs leads to a significant reduction in low-density lipoproteins (LDL) level and a low to moderate level of increase in high-density lipoprotein (HDL) cholesterol in plasma.
Alderete, Benjamin +7 more
core +1 more source