Results 61 to 70 of about 111,376 (287)

Effects of dietary cholesterol on the regulation of total body cholesterol in man

Journal of Lipid Research, 1971
Studies on the interaction of cholesterol absorption, synthesis, and excretion were carried out in eight patients using sterol balance techniques. Absorption of dietary cholesterol was found to increase with intake; up to 1 g of cholesterol was absorbed ...
EDER QUINTÃO, SCOTT M. GRUNDY, E.H. AHRENS, JR.   +2 more
doaj   +1 more source

Advancing the Landscape of RNAi Nanotherapeutics for Ischemic Heart Disease

Advanced Materials, EarlyView.
RNA interference (RNAi) nanomedicine revolutionizes treatment regimens for ischemic heart diseases by enabling tailored, sequence‐anchored gene regulation. This review highlights the recent advances in nanotechnology‐driven RNAi therapeutics for myocardial ischemia and discusses the key design principles that govern efficient delivery, providing ...
Han Gao, Da Pan, Hélder A. Santos
wiley   +1 more source

In vivo effects of anacetrapib on preβ HDL: improvement in HDL remodeling without effects on cholesterol absorption

Journal of Lipid Research, 2013
Cholesteryl ester transfer protein (CETP) transfers cholesteryl ester and triglyceride between HDL and apoB-containing lipoproteins. Anacetrapib (ANA), a reversible inhibitor of CETP, raises HDL cholesterol and lowers LDL cholesterol in dyslipidemic ...
Sheng-Ping Wang, Erin Daniels, Ying Chen, Jose Castro-Perez, Haihong Zhou, Karen O. Akinsanya, Stephen F. Previs, Thomas P. Roddy, Douglas G. Johns   +8 more
doaj   +1 more source

Radiotherapy Enhancement by Gold Nanocluster‐functionalized Nanoliposomes Using Polychromatic Orthovoltage X‐ray Irradiation

Advanced Materials Interfaces, EarlyView.
Lipid drug carriers to which ultra‐small gold nanoparticles were added enabled more efficient radiotherapy of cultured pancreatic cancer tumors. These nanoparticles boosted radiation‐induced damage to tumors by generating more reactive molecules, though higher gold levels are needed for strong benefits.
Nazareth Milagros Carigga Gutierrez, Eaazhisai Kandiah, Sofia Leo, Erwan Dupont, Fabrizio Johnson‐Corrales, Marc‐André Hograindleur, Sarvenaz Keshmiri, Hélène Elleaume, Benoit Busser, Romain Haudecoeur, Véronique Jacob, Anthony Vella, Véronique Josserand, Maxime Henry, Jean‐Luc Coll, Amandine Hurbin, Xavier Le Guével, Mans Broekgaarden   +17 more
wiley   +1 more source

ACAT2 and ABCG5/G8 are both required for efficient cholesterol absorption in mice: evidence from thoracic lymph duct cannulation[S]

Journal of Lipid Research, 2012
The metabolic fate of newly absorbed cholesterol and phytosterol is orchestrated through adenosine triphosphate-binding cassette transporter G5 and G8 heterodimer (G5G8), and acyl CoA:cholesterol acyltransferase 2 (ACAT2). We hypothesized that intestinal
Tam M. Nguyen, Janet K. Sawyer, Kathryn L. Kelley, Matthew A. Davis, Carol R. Kent, Lawrence L. Rudel   +5 more
doaj   +1 more source

Flexible, Integrated‐Porous Microneedle Sensor for Biofluid Sampling and On‐Site Biomarker Detection

Advanced Materials Technologies, EarlyView.
A paper‐integrated porous PGA microneedle array patch capable of both high strength and absorption capacity is proposed. With an image‐processing system, an optimized colorimetric sensor achieves a low limit of detection of 0.09 mm in cholesterol.
Haitao Deng, Heyi Jing, Jongho Park, Beomjoon Kim   +3 more
wiley   +1 more source

Absorption of cholesterol by the gallbladder

Journal of Lipid Research, 1976
To study whether cholesterol is absorbed by the gallbladder, we instilled from 1 to 300 nmoles of [4-14C]cholesterol dissolved in 1 ml of guinea pig bile into the in situ guinea pig gallbladder.
D H Neiderhiser, C K Harmon, H P Roth
doaj   +1 more source

Recent Advances on Thermochromic Inks for Security Applications

Advanced Materials Technologies, EarlyView.
Thermochromic security inks have garnered interest in recent years as security elements for authentication, information encryption, and anti‐counterfeiting. This review outlines different types of thermochromic materials, how they have been developed as functional inks, and how advancements in property enhancement, sustainability, and printing ...
Duarte B. Oliveira, Andreia Araújo, Elvira Fortunato, Rodrigo Martins, Marta C. Corvo, Emanuel Carlos   +5 more
wiley   +1 more source

Changes in cholesterol absorption and cholesterol synthesis caused by ezetimibe and/or simvastatin in men

Journal of Lipid Research, 2009
This study evaluates changes in cholesterol balance in hypercholesterolemic subjects following treatment with an inhibitor of cholesterol absorption or cholesterol synthesis or coadministration of both agents. This was a randomized, double blind, placebo-
Thomas Sudhop, Michael Reber, Diane Tribble, Aditi Sapre, William Taggart, Patrice Gibbons, Thomas Musliner, Klaus von Bergmann, Dieter Lütjohann   +8 more
doaj   +1 more source

Engineered Microfluidic Organoid Systems: New Paradigms for Menopause Mechanism Research and Personalized Medicine

Advanced Materials Technologies, EarlyView.
This review explores the integration of microfluidic technology with organoid systems as an innovative platform for studying menopausea complex multi‐organ condition. By enabling precise simulation of inter‐organ communication and hormone responses, microfluidic organoids offer a physiologically relevant model for investigating menopausal syndrome and ...
Qianyi Zhang, He Huang, Hongliang Dong, Qiang Ma, Hongyan Jin   +4 more
wiley   +1 more source