Results 41 to 50 of about 1,294,493 (295)

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

FEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

Inhibition of lymphatic absorption of cholesterol by cholestane-3β,5α,6β-triol

Journal of Lipid Research, 1969
The effect of cholestane-3β,5α,6β-triol (CT) on the intestinal absorption of cholesterol and oleic acid, as well as the absorption of labeled CT, was studied in lymph duct-cannulated rats.
M. Ito, W.E. Connor, E.J. Blanchette, C.R. Treadwell, George V. Vahouny   +4 more
doaj   +1 more source

Cholesterol Synthesis, Cholesterol Absorption, and Mortality in Hemodialysis Patients [PDF]

Clinical Journal of the American Society of Nephrology, 2012
Summary Background and objectives Recent clinical trials on cholesterol-lowering in patients with CKD yielded conflicting results, which might have resulted from different treatment strategies. Serum cholesterol levels are determined by endogenous synthesis and intestinal absorption, which are differentially ...
Kyrill S, Rogacev, Tobias, Pinsdorf, Oliver, Weingärtner, Markus K, Gerhart, Elena, Welzel, Kai, van Bentum, Julius, Popp, Andreas, Menzner, Danilo, Fliser, Dieter, Lütjohann, Gunnar H, Heine   +10 more
openaire   +2 more sources

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

Molecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani, Dominic Guanzon, Andrew Lai, Katherin Scholz‐Romero, Sarah Reed, Edita Ritmejeryte, Rohan Lourie, Naven Chetty, Kaltin Ferguson, Carlos Salomon   +9 more
wiley   +1 more source

Evidence for multiple complementary pathways for efficient cholesterol absorption in mice

Journal of Lipid Research, 2005
Apolipoprotein B (apoB)-dependent and apoB-independent pathways for cholesterol transport have been described in cultured cells. Here, we show that the apoB-independent pathway involves apoA-I-containing high density lipoproteins (HDLs).
Jahangir Iqbal, M. Mahmood Hussain
doaj   +1 more source

Intestinal cholesterol absorption, treatment with atorvastatin, and cardiovascular risk in hemodialysis patients. [PDF]

, 2015
BACKGROUND Hemodialysis patients are high absorbers of intestinal cholesterol; they benefit less than other patient groups from statin therapy, which inhibits cholesterol synthesis.
Drechsler, Christiane, Ritz, Eberhard, Wanner, Christoph, Baumgartner, Iris, Fauler, Günter, Genser, Bernd, Grammer, Tanja B., Scharnagl, Hubert, Silbernagel, Günther, Krane, Vera, Grammer, Tanja B, März, Winfried   +11 more
core   +2 more sources

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

FEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks, Garth L. Maker, Emily C. Davies, Berin A. Boughton, Samantha Lodge   +4 more
wiley   +1 more source

Lipid composition and cholesterol nucleation time in gallbladder bile of patients with cholesterol gallstones under choleretic treatment with febuprol [PDF]

, 1988
The effect of a new potent choleretic drug (Febuprol) on lipid composition and cholesterol nucleation time in gallbladder bile was studied in 8 patients with cholesterol gallstones.
Paumgartner, Gustav, Pratschke, Ekkehard, Jüngst, Dieter, Brenner, Gerhard   +3 more
core   +1 more source

Influence of class B scavenger receptors on cholesterol flux across the brush border membrane and intestinal absorption

Journal of Lipid Research, 2009
To learn more about how the step of cholesterol uptake into the brush border membrane (BBM) of enterocytes influences overall cholesterol absorption, we measured cholesterol absorption 4 and 24 h after administration of an intragastric bolus of ...
David V. Nguyen, Victor A. Drover, Martin Knopfel, Padmaja Dhanasekaran, Helmut Hauser, Michael C. Phillips   +5 more
doaj   +1 more source

Food Ingredients That Inhibit Cholesterol Absorption. [PDF]

Prev Nutr Food Sci, 2017
Cholesterol is a vital component of the human body. It stabilizes cell membranes and is the precursor of bile acids, vitamin D and steroid hormones. However, cholesterol accumulation in the bloodstream (hypercholesterolemia) can cause atherosclerotic ...
Jesch ED, Carr TP.
europepmc   +2 more sources