Apolipoprotein A‐I (ApoA‐I), the principal protein of HDL, plays a key role in reverse cholesterol transport, inflammation modulation, and plaque stabilization in atherosclerotic cardiovascular disease. Emerging ApoA‐I–based therapies, including CSL112, enhance cholesterol efflux capacity, though definitive reductions in cardiovascular events remain ...
Awais Habib +6 more
wiley +1 more source
The Association of the Cholesterol Efflux Capacity with the Paraoxonase 1 Q192R Genotype and the Paraoxonase Activity. [PDF]
Oniki K +11 more
europepmc +1 more source
Cholesterol efflux capacity of high-density lipoprotein was not associated with cognitive decline and brain structures in older people with diabetes mellitus. [PDF]
Wu Y +5 more
europepmc +1 more source
Central illustration: Pathophysiological mechanisms linking diabetes mellitus and cardiovascular disease. Chronic hyperglycaemia, insulin resistance, and low‐grade inflammation contribute to endothelial dysfunction, myocardial fibrosis, and cardiomyocyte apoptosis.
Lilian Anagnostopoulou +13 more
wiley +1 more source
Cholesterol Efflux Capacity and Its Association with Oxidative Stress in Myocardial Infarction. [PDF]
Endo Y, Sasaki K, Ikewaki K.
europepmc +1 more source
Cholesterol Efflux Capacity and Its Association With Adverse Cardiovascular Events: A Systematic Review and Meta-Analysis. [PDF]
Lee JJ +11 more
europepmc +1 more source
This review synthesises current knowledge on gut microbiome involvement in obesity and hypertension, evaluates microbiome‐based therapeutic strategies, and identifies critical research gaps to guide future investigations aimed at mitigating the dual pandemics.
Andrej Belančić +7 more
wiley +1 more source
Impact of metabolic-associated fatty liver disease on the cholesterol efflux capacity of high-density lipoproteins in adolescents with type 2 diabetes. [PDF]
Orozco Morales JA +10 more
europepmc +1 more source
Effect of CSL112 (apolipoprotein A-I [human]) on cholesterol efflux capacity in Japanese subjects: Findings from a phase I study and a cross-study comparison. [PDF]
Zheng B +10 more
europepmc +1 more source
ABSTRACT This study aimed to determine whether fat metabolism differs between males and females when exposed to extreme exercise‐heat stress. Physically active males (n = 11, 23 ± 4 years, 81.7 ± 11.8 kg, body fat 16.4 ± 6.6%) and females (n = 13, 25 ± 4 years, 60.4 ± 7.1 kg, 24.4 ± 6.7%) completed a 2‐h exercise‐heat tolerance test (40° $\boldsymbol{{}
Margaret C. Morrissey‐Basler +6 more
wiley +1 more source

