Results 221 to 230 of about 24,401 (257)
Cannabidiol (CBD) and cannabigerol (CBG) alleviate hepatic steatosis in obese mice by shifting energy buffering towards phosphocreatine and enhancing lysosomal lipid degradation and trafficking. These effects are associated with increased creatine kinase activity and lysobisphosphatidic acid (LBPA) levels, highlighting a previously unrecognised ...
Radka Kočvarová +12 more
wiley +1 more source
Brain cholesterol homeostasis is tightly regulated and largely independent of peripheral cholesterol. This review proposes a unifying framework in which aging, sex, and related biological stressors, including hypercholesterolemia, neurodegeneration, inflammation, and oxidative stress, converge to disrupt cholesterol homeostasis in the brain ...
Myuri Ruthirakuhan +2 more
wiley +1 more source
Dehnel's Phenomenon in Mammals
Some small mammals, which remain active year‐round, undergo reversible reductions in body size, braincase height, and the mass of internal organs, including the brain, from summer to winter. It is called Dehnel's phenomenon. In this review, we summarise knowledge of the mechanisms, adaptive value, and genetic basis of the phenomenon, and show how new ...
Jan R. E. Taylor +2 more
wiley +1 more source
Leishmania infantum propagated in IDE8 tick cell line in vitro. L. infantum reduces tick cell viability and induces reactive oxygen species production. Lipidic profile of IDE8 tick cell line is altered during Leishmania infection. Abstract Leishmaniasis comprises a group of vector‐borne neglected tropical diseases caused by species of the obligatory ...
Beatriz Filgueiras Silvestre +7 more
wiley +1 more source
Sex differences in the associations of HDL particle concentration and cholesterol efflux capacity with incident coronary artery disease in type 1 diabetes: The RETRO HDLc cohort study. [PDF]
Costacou T +5 more
europepmc +1 more source
Abstract figure legend Gestational Diabetes Mellitus (GDM) impacts on succinate metabolism and angiogenesis in the umbilical cord endothelium. (Left Panel) Succinate levels increase in both maternal and fetal circulation at delivery, with higher concentrations observed in GDM pregnancies compared to controls during late gestation.
Sergiy Klid +13 more
wiley +1 more source
Simvastatin synergizes with cisplatin in cisplatin‐resistant cervical cancer cells through suppression of the caveolin‐1‐mediated PI3K/AKT signaling axis. ABSTRACT Cervical cancer treatment is often hindered by the emergence of cisplatin (DDP) resistance. Increasing evidence has indicated that statins possess anti‐tumor and chemosensitization potential
Yujia Zhou +7 more
wiley +1 more source
Asialoglycoprotein receptor 1 (ASGR1) is linked to lipid metabolism and CAD, but its role in hypertensive CAD patients is unclear. This single‐center study included 345 hypertensive patients (59 non‐CAD, 286 CAD). Plasma ASGR1 was higher in CAD patients, correlated with multiple markers and HDL‐C, had high diagnostic value (better than traditional ...
Ying Liu +12 more
wiley +1 more source
Regulated Cell Death in Idiopathic Pulmonary Fibrosis
This graphical abstract illustrates regulated cell death (RCD) across key pulmonary cell types—including alveolar epithelial cells, fibroblasts, macrophages, and endothelial cells—modulated through a dynamic death modulation network within the IPF microenvironment.
Xiaoyue Pan +10 more
wiley +1 more source

