Results 221 to 230 of about 44,530 (269)

Cholesterol efflux capacity—a new biomarker for cardiovascular risk? [PDF]

Nature Reviews Cardiology, 2014
openaire   +1 more source

Intratumoral Microorganisms in Tumors: Current Understanding and Emerging Therapeutic Strategies

MedComm, Volume 7, Issue 5, May 2026.
Tumors are no longer viewed as sterile but dynamic ecosystems harboring low‐biomass intratumoral microbiota. These microbes, derived from gut, oral cavity, or circulation, shape tumorigenesis and therapy response via core mechanisms: immunomodulation (regulating T cells, macrophages), metabolic reprogramming (SCFAs, indoles, bile acids), chronic ...
Haoling Zhang, Zengkan Du, Ping Lu, Aimin Jiang, Yadong Guo, Yawei Liu, Zhijing Song, Bing Dai, Wangzheqi Zhang   +8 more
wiley   +1 more source

Prdx1 (peroxiredoxin 1) deficiency reduces cholesterol efflux via impaired macrophage lipophagic flux [PDF]

, 2018
Jeong, Se-Jin, Jung, In-hyuk
core   +1 more source

Phenolic Compounds: From Traditional Uses to Innovative Applications and Everything in Between

Molecular Nutrition &Food Research, Volume 70, Issue 9, 13 May 2026.
This review deals with many aspects related to the study of phenolic compounds, starting with advances in extraction, detection, and quantification methods, going through bioavailability, bioactivity, and beneficial health properties, and discussing antioxidant and antimicrobial uses and mechanisms.
Marcela de Sá Barreto da Cunha, Cristina Maria Turim Santos Miguel, Emília Maria França Lima, Uelinton Manoel Pinto, Cláudia Vieira Prudêncio, Svetoslav Dimitrov Todorov   +5 more
wiley   +1 more source

High‐Density Lipoprotein‐Specific Phospholipid Efflux (HDL‐SPE) Assay in Mice

Molecular Nutrition &Food Research, Volume 70, Issue 9, 13 May 2026.
ABSTRACT The recent study by Martínez‐Beamonte et al. provides new insights into how extra virgin olive oil enriched in bioactive compounds may exert anti‐atherogenic effects, by improving high‐density lipoprotein (HDL) function, as determined by the high‐density lipoprotein‐specific phospholipid efflux (HDL‐SPE) assay in Apoe‐deficient mice.
Masaki Sato, Edward B. Neufeld, Masato Hamasaki, Alan T. Remaley, Kazuhiko Kotani   +4 more
wiley   +1 more source

Impaired Cholesterol Efflux Capacity rather than Low HDL-C Reflects Oxidative Stress under Acute Myocardial Infarction. [PDF]

J Atheroscler Thromb
Oniki K, Ogura M, Matsumoto E, Watanabe H, Imafuku T, Seguchi Y, Arima Y, Fujisue K, Yamanaga K, Yamamoto E, Maeda H, Ogata Y, Yoshida M, Harada-Shiba M, Maruyama T, Tsujita K, Saruwatari J.   +16 more
europepmc   +1 more source

Azole antifungal contaminants disrupt mycorrhizal function and risk agricultural sustainability

PLANTS, PEOPLE, PLANET, Volume 8, Issue 3, Page 952-964, May 2026.
Global food production is increasingly threatened by soil degradation, climate change and the rising costs of synthetic fertilisers. Circular agriculture, which promotes resource reuse, is a promising solution, but using treated wastewater and biosolids in farming introduces risks from emerging contaminants like pharmaceutical residues.
Emily K. Durant, Katie J. Field, J. Brett Sallach, Sara Moeskjær, Alex Williams, Laura J. Carter   +5 more
wiley   +1 more source

Mitochondrial Homeostasis in Pancreatic β Cell Function: Mechanisms and Therapeutic Targets for Diabetes

Journal of Diabetes, Volume 18, Issue 5, May 2026.
This review highlights mitochondrial dysfunction as a central driver of pancreatic β cell failure in diabetes, caused by disrupted mitochondrial quality control (MQC), oxidative stress, and impaired organelle communication. Emerging therapies, such as DRAK2 inhibitors and metabolic reprogramming agents, show promise in restoring β cell function by ...
Ruihan Li, Bingqian Zhang, Yuxin Zhang, Yang Yang, Yuting Lu, Jingya Li   +5 more
wiley   +1 more source

From “Passive Supplementation” to “Active Repair”: Melatonin Reshapes the Treatment Paradigm for Late‐Onset Hypogonadism by Targeting Leydig Cell Senescence

Aging Cell, Volume 25, Issue 5, May 2026.
Melatonin restores testosterone production in aging Leydig cells by targeting key pathological drivers, particularly oxidative stress and mitochondrial dysfunction. This approach offers a fundamental strategy to reshape the Late‐onset hypogonadism treatment paradigm.
Hui Wu, Gang Ning, Mintao Jian, Ajian Peng, Haoyu Wang, Bonan Li, Xing Zhou   +6 more
wiley   +1 more source

Effect of Anacetrapib on Cholesterol Efflux Capacity: A Substudy of the DEFINE Trial. [PDF]

J Am Heart Assoc, 2020
Metzinger MP, Saldanha S, Gulati J, Patel KV, El-Ghazali A, Deodhar S, Joshi PH, Ayers C, Rohatgi A.   +8 more
europepmc   +1 more source