Results 241 to 250 of about 44,530 (269)

Cholesterol Efflux Capacity and Atherosclerosis

New England Journal of Medicine, 2011
de Vries, Rindert, Groen, Albert K., Dullaart, Robin P. F.   +2 more
openaire   +9 more sources

Cholesterol efflux capacity: An introduction for clinicians

American Heart Journal, 2016
Epidemiologic studies have shown an inverse correlation between high-density lipoprotein (HDL) cholesterol (HDL-C) levels and cardiovascular disease outcomes. However, the hypothesis of a causal relationship between HDL-C and cardiovascular disease has been challenged by genetic and clinical studies.
Malcolm, Anastasius, Maaike, Kockx, Wendy, Jessup, David, Sullivan, Kerry-Anne, Rye, Leonard, Kritharides   +5 more
openaire   +2 more sources

From HDL-cholesterol to HDL-function: cholesterol efflux capacity determinants

Current Opinion in Lipidology, 2019
Purpose of review The validity of HDL-cholesterol (HDL-C) elevation as a therapeutic target has been questioned, in comparison to enhancing HDL functionality. Cholesterol efflux capacity (CEC) is an in-vitro assay that measures the ability of an individual's HDL to promote cholesterol efflux from cholesterol donor cells such as
David, Rhainds, Jean-Claude, Tardif
openaire   +2 more sources

Modulating cholesterol efflux capacity to improve cardiovascular disease

Current Opinion in Lipidology, 2016
Purpose of review Low HDL-cholesterol (HDL-C) levels are predictive of incident atherosclerotic cardiovascular disease events. However, the use of medication to raise HDL-C levels has not consistently shown clinical benefit. As a result, studies have shifted toward HDL function, specifically cholesterol efflux, which has been ...
Nicholas, Brownell, Anand, Rohatgi
openaire   +2 more sources

Cholesterol efflux capacity in coronary artery disease: a meta-analysis

Coronary Artery Disease, 2020
Objective To quantitatively analyze the association between cholesterol efflux capacity (CEC) and the risk and prognosis of coronary artery disease (CAD). Methods A systematic search of electronic databases for studies published until September 2019 was performed.
Huiming, Ye, Guiyu, Xu, Lihui, Ren, Jianjun, Peng   +3 more
openaire   +2 more sources

Significance of the percentage of cholesterol efflux capacity and total cholesterol efflux capacity in patients with or without coronary artery disease

Heart and Vessels, 2016
We hypothesized that cholesterol efflux capacity is more useful than the lipid profile as a marker of the presence and the severity of coronary artery disease (CAD). Therefore, we investigated the associations between the presence and the severity of CAD and both the percentage of cholesterol efflux capacity and total cholesterol efflux capacity and ...
Kenji, Norimatsu, Takashi, Kuwano, Shin-Ichiro, Miura, Tomohiko, Shimizu, Yuhei, Shiga, Yasunori, Suematsu, Yuiko, Miyase, Sen, Adachi, Ayumi, Nakamura, Satoshi, Imaizumi, Atsushi, Iwata, Hiroaki, Nishikawa, Yoshinari, Uehara, Keijiro, Saku   +13 more
openaire   +2 more sources

Modulation of cholesterol efflux capacity in patients with myocardial infarction

Current Opinion in Cardiology, 2019
Epidemiologic studies consistently demonstrated that patients with coronary artery disease (CAD) and low HDL cholesterol (HDL-C) are more likely to develop major adverse cardiovascular events as compared with those with normal or high HDL. However, several large randomized trials failed to demonstrate that a substantial, pharmacological-based, increase
Silvain, Johanne, Kerneis, Mathieu, Guerin, Maryse, Montalescot, Gilles   +3 more
openaire   +2 more sources

HDL Cholesterol Efflux Capacity: Cardiovascular Risk Factor and Potential Therapeutic Target

Current Atherosclerosis Reports, 2015
Low high-density lipoprotein cholesterol (HDL-C) levels are associated with incident cardiovascular events; however, many therapies targeting increases in HDL-C have failed to show consistent clinical benefit. Thus, focus has recently shifted toward measuring high-density lipoprotein (HDL) function.
Anish, Bhatt, Anand, Rohatgi
openaire   +2 more sources

Cholesterol Efflux Capacity: Choke Point of Reverse Cholesterol Traffic?

Journal of the American College of Cardiology, 2018
Winfried, März, Andreas, Ritsch
openaire   +2 more sources

HDL cholesterol efflux capacity and cardiovascular mortality

Atherosclerosis, 2015
A. Ritsch, A. Duerr, P. Kahler, T. Stojakovic, G. Silbernagel, H. Scharnagl, M.E. Kleber, W. März   +7 more
openaire   +1 more source