Protein markers of dysfunctional HDL in scavenger receptor class B type I deficient mice [PDF]
Journal of Translational Medicine, 2018 Background Scavenger receptor class B type I (SR-BI) plays a key role in high density lipoproteins (HDL) metabolism. SR-BI deficiency in mice results in enhanced susceptibility to atherosclerosis with abnormal large, cholesterol enriched, and functional ...
Jia Cao +5 more
doaj +6 more sources
Farnesoid X receptor induces murine scavenger receptor Class B type I via intron binding. [PDF]
PLoS ONE, 2012 Farnesoid X receptor (FXR) is a nuclear receptor and a key regulator of liver cholesterol and triglyceride homeostasis. Scavenger receptor class B type I (SR-BI) is critical for reverse cholesterol transport (RCT) by transporting high-density lipoprotein
Guodong Li +7 more
doaj +4 more sources
Scavenger receptor class B type I: a multifunctional receptor [PDF]
Annals of the New York Academy of Sciences, 2011 The scavenger receptor class B type I (SR-B1) plays an important role in meditating the uptake of HDL-derived cholesterol and cholesteryl ester in the liver and steroidogenic tissues.
Giuseppe Valacchi +2 more
exaly +5 more sources
Scavenger receptor class B type I as a receptor for oxidized low density lipoprotein [PDF]
Journal of Lipid Research, 2001 Scavenger receptor class B type I (SR-BI) has been established as the primary mediator of the selective transfer of lipids from HDL to mammalian cells.
Kristin Gillotte-Taylor +4 more
doaj +5 more sources
Scavenger Receptor Class B, Type I, a CD36 Related Protein in Macrobrachium nipponense: Characterization, RNA Interference, and Expression Analysis with Different Dietary Lipid Sources [PDF]
International Journal of Genomics, 2016 The scavenger receptor class B, type I (SR-BI), is a member of the CD36 superfamily comprising transmembrane proteins involved in mammalian and fish lipid homeostasis regulation.
Zhili Ding +6 more
doaj +3 more sources
The human scavenger receptor class B type I is a novel candidate receptor for the hepatitis C virus [PDF]
EMBO Journal, 2002 We discovered that the hepatitis C virus (HCV) envelope glycoprotein E2 binds to human hepatoma cell lines independently of the previously proposed HCV receptor CD81.
Cinzia Traboni +2 more
exaly +5 more sources
Zebrafish as outgroup model to study evolution of scavenger receptor class B type I functions
Biochimica Et Biophysica Acta - Molecular and Cell Biology of Lipids, 2023 Background and aims: Scavenger receptor class B1 (SCARB1) -also known as the high-density lipoprotein (HDL) receptor -is a multi-ligand scavenger receptor that is primarily expressed in liver and steroidogenic organs.
Robin A F Verwilligen +2 more
exaly +6 more sources
Lp-PLA2, scavenger receptor class B type I gene (SCARB1) rs10846744 variant, and cardiovascular disease. [PDF]
PLoS ONE, 2018 BackgroundWe previously reported association of SCARB1 SNP rs10846744 with common carotid IMT (cIMT) and cardiovascular disease (CVD) events. Since rs10846744 has been reported in association with Lp-PLA2 mass and activity, we hypothesized that ...
Ani Manichaikul +19 more
doaj +2 more sources
Scavenger receptor class B type I knockout mice develop extensive diet-induced coronary artery atherosclerosis in an age-dependent manner. [PDF]
PLoS ONEObjectiveHomozygous knockout of scavenger receptor class B type I (SR-B1) in mice with atherogenic mutations (such as knockout of the apolipoprotein E or low density lipoprotein receptor genes) results in spontaneous or diet-induced coronary heart ...
Samuel K Lee +9 more
doaj +2 more sources
Erratum. High-Density Lipoproteins Rescue Diabetes-Impaired Angiogenesis via Scavenger Receptor Class B Type I. Diabetes 2016;65:3091-3103. [PDF]
Diabetes, 2017 Disordered neovascularization and impaired wound healing are important contributors to diabetic vascular complications. We recently showed that high-density lipoproteins (HDLs) enhance ischemia-mediated neovascularization, and mounting evidence suggests ...
Tan JT +13 more
europepmc +2 more sources