Results 31 to 40 of about 214 (69)

HDL modification by secretory phospholipase A2 promotes scavenger receptor class B type I interaction and accelerates HDL catabolism

Journal of Lipid Research, 2000
During inflammatory states plasma levels of high density lipoprotein (HDL) cholesterol and apolipoprotein A-I (apoA-I) are reduced. Secretory group IIa phospholipase A2 (sPLA2) is a cytokine-induced acute-phase enzyme associated with HDL. Transgenic mice
Frederick C. de Beer, Patrice M. Connell, J. Yu, Maria C. de Beer, Nancy R. Webb, Deneys R. van der Westhuyzen   +5 more
doaj   +1 more source

Apolipoprotein M promotes cholesterol uptake and efflux from mouse macrophages

FEBS Open Bio, 2021
Apolipoprotein M (ApoM) exhibits various anti‐atherosclerotic functions as a component of high‐density lipoprotein (HDL) particles. Scavenger receptor class B type I (SR‐BI) is a classic HDL receptor that mediates selective cholesterol uptake and ...
Shuang Yao, Fan Zheng, Yang Yu, Yuxia Zhan, Ning Xu, Guanghua Luo, Lu Zheng   +6 more
doaj   +1 more source

Role Analysis of the scarb1 Gene in the Pigmentation of Neocaridina denticulata sinensis

Animals
Body color is a key economic trait for Neocaridina denticulata sinensis, an important ornamental shrimp. Scarb1 may be an important mediator of astaxanthin uptake, changing the shrimp’s body color.
Lili Zhang, Guodong Wang, Haifan Li, Tanjun Zhao   +3 more
doaj   +1 more source

Selective uptake of HDL cholesteryl esters and cholesterol efflux from mouse peritoneal macrophages independent of SR-BI

Journal of Lipid Research, 2006
Scavenger receptor class B type I (SR-BI) mediates the selective uptake of HDL cholesteryl esters (CEs) and facilitates the efflux of unesterified cholesterol. SR-BI expression in macrophages presumably plays a role in atherosclerosis.
May Brundert, Joerg Heeren, Mukaddes Bahar-Bayansar, Anne Ewert, Kathryn J. Moore, Franz Rinninger   +5 more
doaj   +1 more source

Role of cholesteryl ester transfer protein in selective uptake of high density lipoprotein cholesteryl esters by adipocytes

Journal of Lipid Research, 2004
Previous reports attributed cholesteryl ester transfer protein (CETP)-mediated HDL cholesteryl ester (CE) selective uptake to the CETP-mediated transfer of CE from HDL to newly secreted apolipoprotein B-containing lipoproteins, which are then ...
Gerard Vassiliou, Ruth McPherson
doaj   +1 more source

Cholesterol efflux via HDL resecretion occurs when cholesterol transport out of the lysosome is impaireds⃞

Journal of Lipid Research, 2007
Recently, we showed that holo HDL particle uptake and resecretion occur in physiologically relevant cell lines and that HDL uptake is mediated by scavenger receptor class B type I (SR-BI).
Tamara A. Pagler, Angelika Neuhofer, Hildegard Laggner, Wolfgang Strobl, Herbert Stangl   +4 more
doaj   +1 more source

Molecular characterization of rabbit scavenger receptor class B types I and II

Journal of Lipid Research, 2004
To further elucidate the role of scavenger receptor class B type I (SR-BI) in reverse cholesterol transport and in atherogenesis, we performed studies in the rabbit, an animal model displaying a lipoprotein profile similar to that of human, expressing ...
A. Ritsch, I. Tancevski, W. Schgoer, C. Pfeifhofer, R. Gander, P. Eller, B. Foeger, U. Stanzl, J.R. Patsch   +8 more
doaj   +1 more source

SR-BI-directed HDL-cholesteryl ester hydrolysis

Journal of Lipid Research, 2003
We have examined the metabolic fate of HDL cholesteryl ester (CE) delivered to cells expressing scavenger receptor class B type I (SR-BI). Comparison of SR-BI with a related class B scavenger receptor, CD36, showed a greater uptake and a more rapid and ...
Margery A. Connelly, Ginny Kellner-Weibel, George H. Rothblat, David L. Williams   +3 more
doaj   +1 more source

Scavenger receptor class B type I-mediated uptake of serum cholesterol is essential for optimal adrenal glucocorticoid production

Journal of Lipid Research, 2009
Impaired scavenger receptor class B type I (SR-BI)-mediated uptake of HDL-cholesterol esters (HDL-CE) induces adrenal insufficiency in mice. Humans contain an alternative route of HDL-CE clearance, namely through the transfer by cholesteryl ester ...
Menno Hoekstra, Dan Ye, Reeni B. Hildebrand, Ying Zhao, Bart Lammers, Miranda Stitzinger, Johan Kuiper, Theo J.C. Van Berkel, Miranda Van Eck   +8 more
doaj   +1 more source

Hepatic cholesterol and bile acid metabolism and intestinal cholesterol absorption in scavenger receptor class B type I-deficient mice

Journal of Lipid Research, 2001
The scavenger receptor class B type I (SR-BI), which is expressed in the liver and intestine, plays a critical role in cholesterol metabolism in rodents.
Pablo Mardones, Verónica Quiñones, Ludwig Amigo, Mauricio Moreno, Juan Francisco Miquel, Margrit Schwarz, Helena E. Miettinen, Bernardo Trigatti, Monty Krieger, Sonya VanPatten, David E. Cohen, Attilio Rigotti   +11 more
doaj   +1 more source