Results 11 to 20 of about 55,191 (290)

Scavenger receptor class B type I as a receptor for oxidized low density lipoprotein [PDF]

Journal of Lipid Research, 2001
Scavenger receptor class B type I (SR-BI) has been established as the primary mediator of the selective transfer of lipids from HDL to mammalian cells.
Kristin Gillotte-Taylor, Agnès Boullier, Joseph L. Witztum, Daniel Steinberg, Oswald Quehenberger   +4 more
doaj   +5 more sources

Scavenger receptor class B type I is a plasma membrane cholesterol sensor. [PDF]

Circ Res, 2013
Rationale: Signal initiation by the high-density lipoprotein (HDL) receptor scavenger receptor class B, type I (SR-BI), which is important to actions of HDL on endothelium and other processes, requires cholesterol efflux and the C-terminal transmembrane domain.
Saddar S, Carriere V, Lee WR, Tanigaki K, Yuhanna IS, Parathath S, Morel E, Warrier M, Sawyer JK, Gerard RD, Temel RE, Brown JM, Connelly M, Mineo C, Shaul PW.   +14 more
europepmc   +6 more sources

Sterol regulation of scavenger receptor class B type I in macrophages [PDF]

Journal of Lipid Research, 2004
Scavenger receptor class B type I (SR-BI) is expressed in macrophages, but its role in sterol trafficking in these cells remains controversial. We examined the effect of sterol loading on SR-BI expression in human monocytes/macrophages, mouse peritoneal ...
Liqing Yu, Guoqing Cao, Joyce Repa, Herbert Stangl   +3 more
doaj   +3 more sources

Scavenger receptor class B type I: a multifunctional receptor [PDF]

Annals of the New York Academy of Sciences, 2011
The scavenger receptor class B type I (SR‐B1) plays an important role in meditating the uptake of HDL‐derived cholesterol and cholesteryl ester in the liver and steroidogenic tissues. In addition to being ubiquitous, SR‐B1 is a high‐density lipoprotein (HDL) receptor in many tissues, though the mechanism by which SR‐B1 does this is unclear.
VALACCHI, Giuseppe, STICOZZI, Claudia, Y. Lim, A. Pecorelli   +3 more
openaire   +5 more sources

Scavenger receptor class B type I localizes to a late endosomal compartment [PDF]

Journal of Lipid Research, 2008
Scavenger receptor class B type I (SR-BI) has an established role in mediating the selective uptake of cholesterol from HDL in hepatocytes, steroidogenic cells, and other tissues.
Malika Ahras, Thet Naing, Ruth McPherson
doaj   +3 more sources

Remodeling of HDL remnants generated by scavenger receptor class B type I [PDF]

Journal of Lipid Research, 2004
Scavenger receptor class B type I (SR-BI) mediates the selective transfer of cholesteryl ester from HDL to cells. We previously established that SR-BI overexpressed in livers of apolipoprotein A-I-deficient mice processes exogenous human HDL2 to ...
Nancy R. Webb, Maria C. de Beer, Bela F. Asztalos, Nathan Whitaker, Deneys R. van der Westhuyzen, Frederick C. de Beer   +5 more
doaj   +3 more sources

Scavenger receptor class B type I (SR-BI): a versatile receptor with multiple functions and actions. [PDF]

Metabolism, 2014
Scavenger receptor class B type I (SR-BI), is a physiologically relevant HDL receptor that mediates selective uptake of lipoprotein (HDL)-derived cholesteryl ester (CE) in vitro and in vivo. Mammalian SR-BI is a 509-amino acid, ~82 kDa glycoprotein that contains N- and C-terminal cytoplasmic domains, two-transmembrane domains, as well as a large ...
Shen WJ, Hu J, Hu Z, Kraemer FB, Azhar S.   +4 more
europepmc   +6 more sources

Novel Functions of Endothelial Scavenger Receptor Class B Type I. [PDF]

Curr Atheroscler Rep, 2021
Scavenger receptor class B type I (SR-BI) serves a key role in the reverse cholesterol transport in the liver as the high-affinity receptor for HDL. SR-BI is abundantly expressed in endothelium, and earlier works indicate that the receptor mediates anti-atherogenic actions of HDL. However, more recent studies uncovered novel functions of endothelial SR-
Yu L, Dai Y, Mineo C.
europepmc   +3 more sources

Molecular characterization of rabbit scavenger receptor class B types I and II [PDF]

Journal of Lipid Research, 2004
To further elucidate the role of scavenger receptor class B type I (SR-BI) in reverse cholesterol transport and in atherogenesis, we performed studies in the rabbit, an animal model displaying a lipoprotein profile similar to that of human, expressing ...
A. Ritsch, I. Tancevski, W. Schgoer, C. Pfeifhofer, R. Gander, P. Eller, B. Foeger, U. Stanzl, J.R. Patsch   +8 more
doaj   +2 more sources

Scavenger receptor class B type I and immune dysfunctions. [PDF]

Curr Opin Endocrinol Diabetes Obes, 2014
To summarize the recent findings about the roles of scavenger receptor class B type I (SR-BI) in immunity and discuss the underlying mechanisms by which SR-BI prevents immune dysfunctions.SR-BI is well known as a high-density lipoprotein (HDL) receptor playing key roles in HDL metabolism and in protection against atherosclerosis.
Zheng Z, Ai J, Li XA.
europepmc   +3 more sources