Results 11 to 20 of about 38,420,644 (271)

Differentiation-dependent expression and localization of the class B type I scavenger receptor in intestine [PDF]

Journal of Lipid Research, 2001
The current study used the human Caco-2 cell line and mouse intestine to explore the topology of expression of the class B type I scavenger receptor (SR-BI) in intestinal cells.
Sheng F. Cai, R. Jason Kirby, Philip N. Howles, David Y. Hui   +3 more
doaj   +3 more sources

Scavenger receptor class B type I knockout mice develop extensive diet-induced coronary artery atherosclerosis in an age-dependent manner. [PDF]

PLoS ONE
ObjectiveHomozygous knockout of scavenger receptor class B type I (SR-B1) in mice with atherogenic mutations (such as knockout of the apolipoprotein E or low density lipoprotein receptor genes) results in spontaneous or diet-induced coronary heart ...
Samuel K Lee, Ting Xiong, Alexander S Qian, Jeong-Ah Yoo, B Sumayyah H Sokeechand, Mark T Fuller, Peter L Gross, Richard C Austin, Suleiman A Igdoura, Bernardo L Trigatti   +9 more
doaj   +2 more sources

Scavenger Receptor Class B, Type I, a CD36 Related Protein in Macrobrachium nipponense: Characterization, RNA Interference, and Expression Analysis with Different Dietary Lipid Sources [PDF]

International Journal of Genomics, 2016
The scavenger receptor class B, type I (SR-BI), is a member of the CD36 superfamily comprising transmembrane proteins involved in mammalian and fish lipid homeostasis regulation.
Zhili Ding, Na Luo, Youqin Kong, Jingfen Li, Yixiang Zhang, Fang Cao, Jinyun Ye   +6 more
doaj   +2 more sources

Liver receptor homolog 1 controls the expression of the scavenger receptor class B type I [PDF]

The EMBO Reports, 2002
The scavenger receptor class B type I (SR-BI), which mediates selective cellular cholesterol uptake from high-density lipoproteins (HDLs), plays a key role in reverse cholesterol transport. The orphan nuclear receptor liver receptor homolog 1 (LRH-1) and SR-BI are co-expressed in liver and ovary, suggesting that LRH-1 might control the expression of SR-
Schoonjans, Kristina, Annicotte, Jean‐sebastien, Huby, Thierry, Botrugno, Oronza, Fayard, Elisabeth, Ueda, Yukihiko, Chapman, John, Auwerx, Johan   +7 more
openaire   +6 more sources

Scavenger Receptor Class B, Type I: A Promising Immunotherapy Target

Immunotherapy, 2011
Scavenger receptor class B, type I (SR-BI) is a crucial molecule in lipid metabolism, since the interaction of high-density lipoproteins (HDLs) with SR-BI is involved in reverse cholesterol transport and cholesterol efflux. Recent findings also underscore a critical role of SR-BI in antimicrobial and immune responses. SR-BI is not only highly expressed
Jessica, Fioravanti, José, Medina-Echeverz, Pedro, Berraondo   +2 more
openaire   +3 more sources

Microvascular endothelial scavenger receptor class B type I protects against heart failure with preserved ejection fraction by inhibiting T-cell cardiotropism [PDF]

EMBO Molecular Medicine
Cardiac microvascular endothelial cells (CMECs) dysfunction is a well-recognized mediator of heart failure with preserved ejection fraction (HFpEF), but the underlying mechanism remains unclear. Here we find that scavenger receptor class B type I (SR-B1)
Yufei Wu, Xiaomei Yang, Yu Bai, Chenze Li, Peng Wang, Qing Xu, Hui Li, Xiaoli Rao, Yangkai Xu, Jie Chen, Huanhuan Cao, Qi Zhang, Mingming Zhao, Rui Zhan, Xue Fan, Yuedong Hou, Jie Liu, Hong S Lu, Tianyun Wang, Wei Dong Gao, Linzhang Huang, Han Xiao, Lingyun Zu, Alan Daugherty, Mingguo Xu, Lemin Zheng   +25 more
doaj   +2 more sources

Interaction of scavenger receptor class B type I with peroxisomal targeting receptor Pex5p

Biochemical and Biophysical Research Communications, 2003
Scavenger receptor class B type I (SR-BI) is an HDL receptor that mediates selective HDL lipid uptake. Peroxisomes play an important role in lipid metabolism and peroxisomal targeting signal type 1 (PTS1)-containing proteins are translocated to peroxisomes by the peroxisomal targeting import receptor, Pex5p.
Magnus S C, Johnson, Jenny M, Johansson, Per Arne, Svensson, Maria A I, Aberg, Peter S, Eriksson, Lena M S, Carlsson, Björn, Carlsson   +6 more
openaire   +3 more sources

Novel Functions of Endothelial Scavenger Receptor Class B Type I. [PDF]

Curr Atheroscler Rep, 2021
Scavenger receptor class B type I (SR-BI) serves a key role in the reverse cholesterol transport in the liver as the high-affinity receptor for HDL. SR-BI is abundantly expressed in endothelium, and earlier works indicate that the receptor mediates anti-atherogenic actions of HDL. However, more recent studies uncovered novel functions of endothelial SR-
Yu L, Dai Y, Mineo C.
europepmc   +3 more sources

Regulation and splicing of scavenger receptor class B type I in human macrophages and atherosclerotic plaques [PDF]

BMC Cardiovascular Disorders, 2005
Background The protective role of high-density lipoprotein (HDL) in the cardiovascular system is related to its role in the reverse transport of cholesterol from the arterial wall to the liver for subsequent excretion via the bile.
Fagerberg Björn, Thelle Dag S, Mattsson-Hulten Lillemor, Stemme Veronika, Ohlsson Bertil G, Hägg Daniel A, Snäckestrand Magnus SC, Englund Mikael CO, Svensson Per-Arne, Wiklund Olov, Carlsson Lena MS, Carlsson Björn   +11 more
doaj   +3 more sources

Molecular characterization of rabbit scavenger receptor class B types I and II [PDF]

Journal of Lipid Research, 2004
To further elucidate the role of scavenger receptor class B type I (SR-BI) in reverse cholesterol transport and in atherogenesis, we performed studies in the rabbit, an animal model displaying a lipoprotein profile similar to that of human, expressing ...
A. Ritsch, I. Tancevski, W. Schgoer, C. Pfeifhofer, R. Gander, P. Eller, B. Foeger, U. Stanzl, J.R. Patsch   +8 more
doaj   +2 more sources