Results 21 to 30 of about 25,031 (241)

Extensive diet-induced atherosclerosis in scavenger receptor class B type 1-deficient mice is associated with substantial leukocytosis and elevated vascular cell adhesion molecule-1 expression in coronary artery endothelium

open access: yesFrontiers in Physiology, 2023
High levels of low density lipoprotein (LDL) cholesterol and low levels of high density lipoprotein (HDL) cholesterol are risk factors for cardiovascular disease. Mice that lack genes involved in the clearance of LDL from the bloodstream, such as the LDL
Mark T. Fuller   +15 more
doaj   +1 more source

Dimerization of the scavenger receptor class B type I

open access: yesJournal of Lipid Research, 2004
This study has examined the dimeric/oligomeric forms of scavenger receptor class B type I (SR-BI) and its alternatively spliced form, SR-BII, in a diverse group of cells and tissues: i.e., normal and hormonally altered tissues of mice and rats as well as
Eve Reaven   +4 more
doaj   +1 more source

Sterol regulation of scavenger receptor class B type I in macrophages

open access: yesJournal of Lipid Research, 2004
Scavenger receptor class B type I (SR-BI) is expressed in macrophages, but its role in sterol trafficking in these cells remains controversial. We examined the effect of sterol loading on SR-BI expression in human monocytes/macrophages, mouse peritoneal ...
Liqing Yu   +3 more
doaj   +1 more source

Scavenger receptor class B type I localizes to a late endosomal compartment

open access: yesJournal of Lipid Research, 2008
Scavenger receptor class B type I (SR-BI) has an established role in mediating the selective uptake of cholesterol from HDL in hepatocytes, steroidogenic cells, and other tissues.
Malika Ahras, Thet Naing, Ruth McPherson
doaj   +1 more source

Remodeling of HDL remnants generated by scavenger receptor class B type I

open access: yesJournal of Lipid Research, 2004
Scavenger receptor class B type I (SR-BI) mediates the selective transfer of cholesteryl ester from HDL to cells. We previously established that SR-BI overexpressed in livers of apolipoprotein A-I-deficient mice processes exogenous human HDL2 to ...
Nancy R. Webb   +5 more
doaj   +1 more source

Scavenger receptor-BI is a receptor for lipoprotein(a)

open access: yesJournal of Lipid Research, 2013
Scavenger receptor class B type I (SR-BI) is a multi-ligand receptor that binds a variety of lipoproteins, including high density lipoprotein (HDL) and low density lipoprotein (LDL), but lipoprotein(a) [Lp(a)] has not been investigated as a possible ...
Xiao-Ping Yang   +9 more
doaj   +1 more source

Scavenger receptor class B type I reduces cholesterol absorption in cultured enterocyte CaCo-2 cells1

open access: yesJournal of Lipid Research, 2004
Scavenger receptor class B type I (SR-BI) mediates selective uptake of cholesteryl esters from HDL as well as efflux of cellular free cholesterol to HDL. It is unclear whether the receptor is involved in intestinal cholesterol absorption.
Lei Cai   +6 more
doaj   +1 more source

Differentiation-dependent expression and localization of the class B type I scavenger receptor in intestine

open access: yesJournal of Lipid Research, 2001
The current study used the human Caco-2 cell line and mouse intestine to explore the topology of expression of the class B type I scavenger receptor (SR-BI) in intestinal cells.
Sheng F. Cai   +3 more
doaj   +1 more source

Liver receptor homolog 1 controls the expression of the scavenger receptor class B type I [PDF]

open access: yes, 2002
The scavenger receptor class B type I (SR-BI), which mediates selective cellular cholesterol uptake from high-density lipoproteins (HDLs), plays a key role in reverse cholesterol transport. The orphan nuclear receptor liver receptor homolog 1 (LRH-1) and
Schoonjans, Kristina   +15 more
core   +1 more source

DataSheet1_Extensive diet-induced atherosclerosis in scavenger receptor class B type 1-deficient mice is associated with substantial leukocytosis and elevated vascular cell adhesion molecule-1 expression in coronary artery endothelium.PDF

open access: yes, 2023
High levels of low density lipoprotein (LDL) cholesterol and low levels of high density lipoprotein (HDL) cholesterol are risk factors for cardiovascular disease. Mice that lack genes involved in the clearance of LDL from the bloodstream, such as the LDL
Melissa E. MacDonald (14392422)   +8 more
core   +1 more source

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