Results 21 to 30 of about 25,031 (241)

Extensive diet-induced atherosclerosis in scavenger receptor class B type 1-deficient mice is associated with substantial leukocytosis and elevated vascular cell adhesion molecule-1 expression in coronary artery endothelium

Frontiers in Physiology, 2023
High levels of low density lipoprotein (LDL) cholesterol and low levels of high density lipoprotein (HDL) cholesterol are risk factors for cardiovascular disease. Mice that lack genes involved in the clearance of LDL from the bloodstream, such as the LDL
Mark T. Fuller, Mark T. Fuller, Omid Dadoo, Omid Dadoo, Ting Xiong, Ting Xiong, Pardh Chivukula, Pardh Chivukula, Melissa E. MacDonald, Samuel K. Lee, Samuel K. Lee, Richard C. Austin, Richard C. Austin, Suleiman A. Igdoura, Bernardo L. Trigatti, Bernardo L. Trigatti   +15 more
doaj   +1 more source

Dimerization of the scavenger receptor class B type I

Journal of Lipid Research, 2004
This study has examined the dimeric/oligomeric forms of scavenger receptor class B type I (SR-BI) and its alternatively spliced form, SR-BII, in a diverse group of cells and tissues: i.e., normal and hormonally altered tissues of mice and rats as well as
Eve Reaven, Yuan Cortez, Susan Leers-Sucheta, Ann Nomoto, Salman Azhar   +4 more
doaj   +1 more source

Sterol regulation of scavenger receptor class B type I in macrophages

Journal of Lipid Research, 2004
Scavenger receptor class B type I (SR-BI) is expressed in macrophages, but its role in sterol trafficking in these cells remains controversial. We examined the effect of sterol loading on SR-BI expression in human monocytes/macrophages, mouse peritoneal ...
Liqing Yu, Guoqing Cao, Joyce Repa, Herbert Stangl   +3 more
doaj   +1 more source

Scavenger receptor class B type I localizes to a late endosomal compartment

Journal of Lipid Research, 2008
Scavenger receptor class B type I (SR-BI) has an established role in mediating the selective uptake of cholesterol from HDL in hepatocytes, steroidogenic cells, and other tissues.
Malika Ahras, Thet Naing, Ruth McPherson
doaj   +1 more source

Remodeling of HDL remnants generated by scavenger receptor class B type I

Journal of Lipid Research, 2004
Scavenger receptor class B type I (SR-BI) mediates the selective transfer of cholesteryl ester from HDL to cells. We previously established that SR-BI overexpressed in livers of apolipoprotein A-I-deficient mice processes exogenous human HDL2 to ...
Nancy R. Webb, Maria C. de Beer, Bela F. Asztalos, Nathan Whitaker, Deneys R. van der Westhuyzen, Frederick C. de Beer   +5 more
doaj   +1 more source

Scavenger receptor-BI is a receptor for lipoprotein(a)

Journal of Lipid Research, 2013
Scavenger receptor class B type I (SR-BI) is a multi-ligand receptor that binds a variety of lipoproteins, including high density lipoprotein (HDL) and low density lipoprotein (LDL), but lipoprotein(a) [Lp(a)] has not been investigated as a possible ...
Xiao-Ping Yang, Marcelo J. Amar, Boris Vaisman, Alexander V. Bocharov, Tatyana G. Vishnyakova, Lita A. Freeman, Roger J. Kurlander, Amy P. Patterson, Lewis C. Becker, Alan T. Remaley   +9 more
doaj   +1 more source

Scavenger receptor class B type I reduces cholesterol absorption in cultured enterocyte CaCo-2 cells1

Journal of Lipid Research, 2004
Scavenger receptor class B type I (SR-BI) mediates selective uptake of cholesteryl esters from HDL as well as efflux of cellular free cholesterol to HDL. It is unclear whether the receptor is involved in intestinal cholesterol absorption.
Lei Cai, Erik R.M. Eckhardt, Wei Shi, Zhenze Zhao, Munira Nasser, Willem J.S. de Villiers, Deneys R. van der Westhuyzen   +6 more
doaj   +1 more source

Differentiation-dependent expression and localization of the class B type I scavenger receptor in intestine

Journal of Lipid Research, 2001
The current study used the human Caco-2 cell line and mouse intestine to explore the topology of expression of the class B type I scavenger receptor (SR-BI) in intestinal cells.
Sheng F. Cai, R. Jason Kirby, Philip N. Howles, David Y. Hui   +3 more
doaj   +1 more source

Liver receptor homolog 1 controls the expression of the scavenger receptor class B type I [PDF]

, 2002
The scavenger receptor class B type I (SR-BI), which mediates selective cellular cholesterol uptake from high-density lipoproteins (HDLs), plays a key role in reverse cholesterol transport. The orphan nuclear receptor liver receptor homolog 1 (LRH-1) and
Schoonjans, Kristina, Huby, Thierry, Yukihiko Ueda, Annicotte, Jean-Sebastien, Oronza A. Botrugno, Thierry Huby, Fayard, Elisabeth, Auwerx, Johan, Jean‐Sebastien Annicotte, Kristina Schoonjans, Botrugno, Oronza A., Chapman, John, John Chapman, Johan Auwerx, Ueda, Yukihiko, Elisabeth Fayard   +15 more
core   +1 more source

DataSheet1_Extensive diet-induced atherosclerosis in scavenger receptor class B type 1-deficient mice is associated with substantial leukocytosis and elevated vascular cell adhesion molecule-1 expression in coronary artery endothelium.PDF

, 2023
High levels of low density lipoprotein (LDL) cholesterol and low levels of high density lipoprotein (HDL) cholesterol are risk factors for cardiovascular disease. Mice that lack genes involved in the clearance of LDL from the bloodstream, such as the LDL
Melissa E. MacDonald (14392422), Ting Xiong (1302621), Pardh Chivukula (14392419), Samuel K. Lee (14392425), Suleiman A. Igdoura (14392431), Bernardo L. Trigatti (445281), Richard C. Austin (14392428), Omid Dadoo (445278), Mark T. Fuller (14392416)   +8 more
core   +1 more source