Results 21 to 30 of about 214 (69)

Hepatic lipase mediates an increase in selective uptake of HDL-associated cholesteryl esters by cells in culture independent from SR-BI

open access: yesJournal of Lipid Research, 2003
Scavenger receptor class B type I (SR-BI) mediates the selective uptake of HDL cholesteryl esters (CEs) by the liver. Hepatic lipase (HL) promotes this lipid uptake independent from lipolysis.
May Brundert   +3 more
doaj   +1 more source

C323 of SR-BI is required for SR-BI-mediated HDL binding and cholesteryl ester uptake[S]

open access: yesJournal of Lipid Research, 2011
Scavenger receptor BI (SR-BI) is an HDL receptor. It binds HDL and mediates the uptake of cholesteryl ester from HDL. Early studies have pointed out that the extracellular domain of SR-BI is critical for SR-BI-mediated cholesteryl ester uptake.
Ling Guo   +4 more
doaj   +1 more source

Quantitative analysis of SR-BI-dependent HDL retroendocytosis in hepatocytes and fibroblasts

open access: yesJournal of Lipid Research, 2006
Previous studies have suggested that HDL retroendocytosis may play a role in scavenger receptor class B type I (SR-BI)-dependent selective lipid uptake in a cell-specific manner.
Bing Sun   +4 more
doaj   +1 more source

Regulation of the selective uptake of cholesteryl esters from high density lipoproteins by sphingomyelin

open access: yesJournal of Lipid Research, 2005
Although sphingomyelin (SM) is a major phospholipid in lipoproteins as well as in the membrane rafts where the scavenger receptor class B type I (SR-BI) is localized, its possible role in the selective uptake of cholesteryl ester (CE) by the SR-BI ...
Papasani V. Subbaiah   +2 more
doaj   +1 more source

LDLs stimulate p38 MAPKs and wound healing through SR-BI independently of Ras and PI3 kinases⃞

open access: yesJournal of Lipid Research, 2009
Intracellular signals elicited by LDLs are likely to play a role in the pathogenesis associated with increased LDL blood levels. We have previously determined that LDL stimulation of human skin fibroblasts, used as a model system for adventitial ...
Natasa Bulat   +2 more
doaj   +1 more source

Scavenger receptor class B type I affects cholesterol homeostasis by magnifying cholesterol flux between cells and HDL

open access: yesJournal of Lipid Research, 2001
Results from several laboratories clearly indicate that expression of scavenger receptor class B type I (SR-BI) enhances the bidirectional flux of cholesterol between cells and lipoproteins.
Margarita de la Llera-Moya   +7 more
doaj   +1 more source

Altered adrenal gland cholesterol metabolism in the apoE-deficient mouse

open access: yesJournal of Lipid Research, 2002
Previous studies suggest the hypothesis that apoE produced by adrenocortical cells modulates cellular cholesterol metabolism to enhance the storage of esterified cholesterol (4444411) at the expense of cholesterol delivery to the steroidogenic pathway ...
Fayanne E. Thorngate   +3 more
doaj   +1 more source

Distinct mechanisms for OxLDL uptake and cellular trafficking by class B scavenger receptors CD36 and SR-BI

open access: yesJournal of Lipid Research, 2007
Modified forms of LDL, including oxidized low density lipoprotein (OxLDL), contribute to macrophage lipid accumulation in the vessel wall. Despite the pathophysiological importance of uptake pathways for OxLDL, the molecular details of OxLDL endocytosis ...
Bing Sun   +5 more
doaj   +1 more source

Regulation of scavenger receptor class B type I in hamster liver and Hep3B cells by endotoxin and cytokines

open access: yesJournal of Lipid Research, 2001
Multiple changes in HDL metabolism occur during infection and inflammation that could potentially impair the antiatherogenic functions of HDL. Scavenger receptor class B type I (SR-BI) promotes cholesterol efflux from peripheral cells and mediates ...
Weerapan Khovidhunkit   +4 more
doaj   +1 more source

Scavenger Receptor Class B, Type I, a CD36 Related Protein in Macrobrachium nipponense: Characterization, RNA Interference, and Expression Analysis with Different Dietary Lipid Sources

open access: yesInternational Journal of Genomics, 2016
The scavenger receptor class B, type I (SR-BI), is a member of the CD36 superfamily comprising transmembrane proteins involved in mammalian and fish lipid homeostasis regulation.
Zhili Ding   +6 more
doaj   +1 more source

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