Interferon alpha bioactivity critically depends on Scavenger receptor class B type I function. [PDF]
Scavenger receptor class B type I (SR-B1) binds pathogen-associated molecular patterns participating in the regulation of the inflammatory reaction but there is no information regarding potential interactions between SR-B1 and the interferon system.
Vasquez M +13 more
europepmc +4 more sources
Human scavenger receptor class B type I variants, lipid traits, and cardiovascular disease. [PDF]
Over the years, pioneering work from Monty Krieger’s laboratory has solidified the role of scavenger receptor class B type I (SR-BI) as a physiologically relevant lipoprotein receptor, especially in mouse models.1,2 It is safe to conclude that the complete absence of SR-BI in mice is associated with significant increases in circulating high-density ...
Vickers KC, Rodriguez A.
europepmc +4 more sources
Transcriptional Regulation of Rat Scavenger Receptor Class B Type I Gene [PDF]
The scavenger receptor class B type I (SR-BI) mediates the selective transport of lipids from high density lipoprotein to cells and plays an important role in the reverse uptake of cholesterol to the liver and in the delivery of substrates for steroidogenesis in steroidogenic organs.
T, Mizutani +3 more
openaire +2 more sources
Scavenger receptor class B, type I (Scarb1) deficiency promotes osteoblastogenesis but stunts terminal osteocyte differentiation. [PDF]
Scavenger receptor class B type I (SR-BI), the Scarb1 gene product, is a high-density lipoprotein (HDL) receptor which was shown to influence bone metabolism. Its absence in mice is associated with alterations of the glucocorticoid/adrenocorticotropic hormone axis, and translated in high bone mass and enhanced bone formation.
Martineau C +3 more
europepmc +4 more sources
Hepatoma cell density promotes claudin-1 and scavenger receptor BI expression and hepatitis C virus internalization. [PDF]
Hepatitis C virus (HCV) entry occurs via a pH- and clathrin-dependent endocytic pathway and requires a number of cellular factors, including CD81, the tight-junction proteins claudin 1 (CLDN1) and occludin, and scavenger receptor class B member I (SR-BI).
Balfe, Peter +5 more
core +2 more sources
SCARB2/LIMP-2 Regulates IFN Production of Plasmacytoid Dendritic Cells by Mediating Endosomal Translocation of TLR9 and Nuclear Translocation of IRF7 [PDF]
Scavenger receptor class B, member 2 (SCARB2) is essential for endosome biogenesis and reorganization and serves as a receptor for both β-glucocerebrosidase and enterovirus 71. However, little is known about its function in innate immune cells.
Chaperot, L. +13 more
core +1 more source
The hepatoadrenal syndrome: A common yet unrecognized clinical condition [PDF]
Objective: Adrenal failure is common in critically ill patients, particularly those with sepsis. As liver failure and sepsis are both associated with increased circulating levels of endotoxin and proinflammatory mediators and reduced levels of apoprotein-
Acton +51 more
core +1 more source
The Helicobacter cinaedi antigen CAIP participates in atherosclerotic inflammation by promoting the differentiation of macrophages in foam cells [PDF]
open12siopenD'Elios, Mario Milco; Vallese, Francesca; Capitani, Nagaja; Benagiano, Marisa; Bernardini, Maria Lina; Rossi, Mirko; Rossi, Gianpaolo; Ferrari, Mauro; Baldari, Cosima Tatiana; Zanotti, Giuseppe; DE BERNARD, Marina; Codolo, GaiaD'Elios, Mario ...
core +1 more source
Scavenger receptor-BI is a receptor for lipoprotein(a)
Scavenger receptor class B type I (SR-BI) is a multi-ligand receptor that binds a variety of lipoproteins, including high density lipoprotein (HDL) and low density lipoprotein (LDL), but lipoprotein(a) [Lp(a)] has not been investigated as a possible ...
Xiao-Ping Yang +9 more
doaj +1 more source
Oxidized low-density lipoprotein inhibits hepatitis C virus cell entry in human hepatoma cells. [PDF]
Cell entry of hepatitis C virus, pseudoparticles (HCVpp) and cell culture grown virus (HCVcc), requires the interaction of viral glycoproteins with CD81 and other as yet unknown cellular factors.
Boullier, Agnès +6 more
core +1 more source

