Results 21 to 30 of about 38,420,644 (271)

Expression of scavenger receptor class B type I in gallbladder columnar epithelium

Journal of Gastroenterology and Hepatology, 2002
AbstractBackgroundThe lipid content of bile may be modified by the gallbladder epithelium. Recent studies indicate that cholesterol can be absorbed from bile and that this can be enhanced by apolipoprotein (apo) A‐I. SR‐BI is a multifunctional receptor capable of binding a wide array of native or modified lipoproteins, phospholipid or bile acid ...
Magnus S C, Johnson, Per-Arne, Svensson, Jan, Borén, Håkan, Billig, Lena M S, Carlsson, Björn, Carlsson   +5 more
openaire   +3 more sources

Contribution of receptors to 'Neisseria meningitidis' interactions with human macrophages [PDF]

, 2004
N. meningitidis is a gram-negative human pathogen that invades human cells, evades immune responses and goes on to cause meningococcal disease, sepsis and death.
Abdillahi, Fatumo Abdi
core   +6 more sources

Scavenger receptor class B type I and immune dysfunctions. [PDF]

Curr Opin Endocrinol Diabetes Obes, 2014
To summarize the recent findings about the roles of scavenger receptor class B type I (SR-BI) in immunity and discuss the underlying mechanisms by which SR-BI prevents immune dysfunctions.SR-BI is well known as a high-density lipoprotein (HDL) receptor playing key roles in HDL metabolism and in protection against atherosclerosis.
Zheng Z, Ai J, Li XA.
europepmc   +3 more sources

The role of scavenger receptor B-I in hepatitis C virus attachment and entry. [PDF]

, 2009
Hepatitis C Virus (HCV) poses a global health problem, leading to progressive disease often culminating in conditions such as hepatocellular carcinoma.
Grove, Joseph
core   +7 more sources

Extensive diet-induced atherosclerosis in scavenger receptor class B type 1-deficient mice is associated with substantial leukocytosis and elevated vascular cell adhesion molecule-1 expression in coronary artery endothelium

Frontiers in Physiology, 2023
High levels of low density lipoprotein (LDL) cholesterol and low levels of high density lipoprotein (HDL) cholesterol are risk factors for cardiovascular disease. Mice that lack genes involved in the clearance of LDL from the bloodstream, such as the LDL
Mark T. Fuller, Mark T. Fuller, Omid Dadoo, Omid Dadoo, Ting Xiong, Ting Xiong, Pardh Chivukula, Pardh Chivukula, Melissa E. MacDonald, Samuel K. Lee, Samuel K. Lee, Richard C. Austin, Richard C. Austin, Suleiman A. Igdoura, Bernardo L. Trigatti, Bernardo L. Trigatti   +15 more
doaj   +1 more source

Scavenger receptor class B type I (SR-BI): a versatile receptor with multiple functions and actions. [PDF]

Metabolism, 2014
Scavenger receptor class B type I (SR-BI), is a physiologically relevant HDL receptor that mediates selective uptake of lipoprotein (HDL)-derived cholesteryl ester (CE) in vitro and in vivo. Mammalian SR-BI is a 509-amino acid, ~82 kDa glycoprotein that contains N- and C-terminal cytoplasmic domains, two-transmembrane domains, as well as a large ...
Shen WJ, Hu J, Hu Z, Kraemer FB, Azhar S.   +4 more
europepmc   +4 more sources

Human scavenger receptor class B type I variants, lipid traits, and cardiovascular disease. [PDF]

Circ Cardiovasc Genet, 2014
Over the years, pioneering work from Monty Krieger’s laboratory has solidified the role of scavenger receptor class B type I (SR-BI) as a physiologically relevant lipoprotein receptor, especially in mouse models.1,2 It is safe to conclude that the complete absence of SR-BI in mice is associated with significant increases in circulating high-density ...
Vickers KC, Rodriguez A.
europepmc   +4 more sources

Class A scavenger receptor 1 (MSR1) restricts hepatitis C virus replication by mediating toll-like receptor 3 recognition of viral RNAs produced in neighboring cells [PDF]

, 2013
Persistent infections with hepatitis C virus (HCV) may result in life-threatening liver disease, including cirrhosis and cancer, and impose an important burden on human health.
McGivern, David R., Fengyu Hu, Daisuke Yamane (206804), David R McGivern, Hu, Fengyu, Hiromichi Dansako (357935), Nobuyuki Kato (235685), Christoph Welsch (22852), Stanley M. Lemon (30543), Daisuke Yamane, Christoph Welsch, Welsch, Christoph, David R. McGivern (415119), Lemon, Stanley M., Kato, Nobuyuki, Fengyu Hu (415120), Dansako, Hiromichi, Stanley M Lemon, Yamane, Daisuke, Nobuyuki Kato, Hiromichi Dansako   +20 more
core   +1 more source

Adaptation of hepatitis C virus to mouse CD81 permits infection of mouse cells in the absence of human entry factors [PDF]

, 2010
Hepatitis C virus (HCV) naturally infects only humans and chimpanzees. The determinants responsible for this narrow species tropism are not well defined.
Christiane Brohm, Kathrin Hueging, Michael Ott, Hueging, Kathrin, Brohm, Christiane, Ott, Michael, Bitzegeio, Julia, Dorothea Bankwitz, Herrmann, Eva, Sibylle Haid, Thomas Pietschmann, Mirjam B. Zeisel, Baumert, Thomas F, Iken, Marcus, Haid, Sibylle, Marcus Iken, Julia Bitzegeio, Thomas F. Baumert, Zeisel, Mirjam B, Thomas F Baumert, Mirjam B Zeisel, Eva Herrmann, Baumert, Thomas, Bankwitz, Dorothea, Zeisel, Mirjam B., Pietschmann, Thomas   +25 more
core   +2 more sources

Transcriptional Regulation of Rat Scavenger Receptor Class B Type I Gene [PDF]

Journal of Biological Chemistry, 2000
The scavenger receptor class B type I (SR-BI) mediates the selective transport of lipids from high density lipoprotein to cells and plays an important role in the reverse uptake of cholesterol to the liver and in the delivery of substrates for steroidogenesis in steroidogenic organs.
T, Mizutani, K, Yamada, T, Minegishi, K, Miyamoto   +3 more
openaire   +2 more sources