Results 1 to 10 of about 1,762,196 (253)

C323 of SR-BI is required for SR-BI-mediated HDL binding and cholesteryl ester uptake[S]

Journal of Lipid Research, 2011
Scavenger receptor BI (SR-BI) is an HDL receptor. It binds HDL and mediates the uptake of cholesteryl ester from HDL. Early studies have pointed out that the extracellular domain of SR-BI is critical for SR-BI-mediated cholesteryl ester uptake.
Ling Guo, Min Chen, Zhiqing Song, Alan Daugherty, Xiang-An Li   +4 more
doaj   +2 more sources

HCV 3a core protein increases lipid droplet cholesteryl ester content via a mechanism dependent on sphingolipid biosynthesis.

PLoS ONE, 2014
Hepatitis C virus (HCV) infected patients often develop steatosis and the HCV core protein alone can induce this phenomenon. To gain new insights into the pathways leading to steatosis, we performed lipidomic profiling of HCV core protein expressing-Huh ...
Ursula Loizides-Mangold, Sophie Clément, Alba Alfonso-Garcia, Emilie Branche, Stéphanie Conzelmann, Clotilde Parisot, Eric O Potma, Howard Riezman, Francesco Negro   +8 more
doaj   +2 more sources

Kinetic characteristics and regulation of HDL cholesteryl ester and apolipoprotein transport in the apoA-I-/- mouse

Journal of Lipid Research, 1998
The concentration dependence and tissue distribution of high density lipoprotein (HDL) cholesteryl ester and apolipoprotein (apo) transport were determined in apoA-I knockout mice (apoA-I-/-) that lack normal HDL in plasma. Rates of HDL cholesteryl ester
D K Spady, Laura A Woollett, Helen H Hobbs   +2 more
exaly   +3 more sources

Abnormal cholesterol–cholesteryl ester metabolism impairs mouse oocyte quality during ovarian aging [PDF]

Cellular & Molecular Biology Letters
Background Ovarian aging-induced decline in oocyte quality has been a main issue in women of advanced maternal age. However, the potential mechanism remains elusive, and there are no effective strategies to ameliorate aged oocyte quality.
Sainan Zhang, Bichun Guo, Junshun Fang, Shanshan Wang, Yicen Liu, Die Wu, Nannan Kang, Yang Zhang, Xin Zhen, Guijun Yan, Lijun Ding, Haixiang Sun, Chuanming Liu   +12 more
doaj   +2 more sources

Macrophage cholesteryl ester mobilization and atherosclerosis [PDF]

Vascular Pharmacology, 2010
Accumulation of cholesteryl esters (CE) stored as cytoplasmic lipid droplets is the main characteristic of macrophage foam cells that are central to the development of atherosclerotic plaques. Since only unesterified or free cholesterol (FC) can be effluxed from the cells to extracellular cholesterol acceptors, hydrolysis of CE is the obligatory first ...
Shobha, Ghosh, Bin, Zhao, Jinghua, Bie, Jingmei, Song   +3 more
openaire   +3 more sources

Acyl unsaturation and cholesteryl ester miscibility in surfaces. Formation of lecithin-cholesteryl ester complexes

Journal of Lipid Research, 1987
The surface behavior of a series of cholesteryl esters was studied in mixtures with a model phospholipid, 1-palmitoyl-2-oleoyl phosphatidylcholine. The cholesteryl esters were representative of the predominant forms occurring naturally and qualitative ...
J M Smaby, H L Brockman
doaj   +3 more sources

Apolipoprotein CI is a physiological regulator of cholesteryl ester transfer protein activity in human plasma but not in rabbit plasma

Journal of Lipid Research, 2009
Plasma cholesteryl ester transfer protein (CETP) activity is high in rabbits, intermediate in humans, and nondetectable in rodents. Human apolipoprotein CI (apoCI) was found to be a potent inhibitor of CETP.
Jean-Paul Pais de Barros, Aurélia Boualam, Thomas Gautier, Laure Dumont, Bruno Vergès, David Masson, Laurent Lagrost   +6 more
doaj   +2 more sources

Plasma cholesteryl ester transfer protein

Journal of Lipid Research, 1993
A. Tall
openaire   +4 more sources

Cholesteryl ester transfer protein (CETP) as a drug target for cardiovascular disease

Nature Communications, 2021
Development of cholesteryl ester transfer protein (CETP) inhibitors for coronary heart disease (CHD) has yet to deliver licensed medicines. To distinguish compound from drug target failure, we compared evidence from clinical trials and drug target ...
A. Schmidt, N. Hunt, M. Gordillo-Marañón, P. Charoen, F. Drenos, M. Kivimaki, D. Lawlor, C. Giambartolomei, O. Papacosta, N. Chaturvedi, J. Bis, C. O’Donnell, G. Wannamethee, A. Wong, J. Price, A. Hughes, T. Gaunt, N. Franceschini, D. Mook-Kanamori, M. Zwierzyna, R. Sofat, A. Hingorani, C. Finan   +22 more
semanticscholar   +1 more source

Prostate cancer cell proliferation is influenced by LDL-cholesterol availability and cholesteryl ester turnover

Cancer & Metabolism, 2022
Background Prostate cancer growth is driven by androgen receptor signaling, and advanced disease is initially treatable by depleting circulating androgens.
Nikki L Raftopulos, Tinashe C. Washaya, Andreas Niederprüm, Antonia Egert, Mariam F. Hakeem-Sanni, Bianca Varney, A. Aishah, Mariya L. Georgieva, Ellinor Olsson, Diandra Z. dos Santos, Z. D. Nassar, B. Cochran, Shilpa R. Nagarajan, Meghna S. Kakani, Jordan F Hastings, D. Croucher, K. Rye, L. Butler, T. Grewal, A. Hoy   +19 more
semanticscholar   +1 more source