Results 31 to 40 of about 254,209 (239)
Cholesteryl ethers are nonhydrolyzable tracers of cholesteryl esters. We report here that the ethers are not legitimate tracers of esters in systems involving plasma cholesteryl ester transfer activity.
S R Green +3 more
doaj +1 more source
Triglyceride and cholesteryl ester hydrolysis in a cell culture model of smooth muscle foam cells.
Cultured rabbit aortic smooth muscle cells were converted to foam cells by exposure to sonicated lipid droplets of defined composition using an inverted culture technique. Uptake of the lipid droplets by the cells was shown to be dependent on the time of
L K Minor, G H Rothblat, J M Glick
doaj +1 more source
Cholesterol exists within the hepatocyte as free cholesterol and cholesteryl ester. The proportion of intrahepatic cholesterol in the free or ester forms is governed in part by the rate of cholesteryl ester formation by acyl-coenzyme A:cholesterol ...
B G Stone +3 more
doaj +1 more source
Rat adrenal uptake and metabolism of high density lipoprotein cholesteryl ester [PDF]
Metabolism of high density lipoprotein (HDL) cholesteryl ester (CE) by cultured rat adrenal cells was studied. Addition of [3H]CE-HDL to cells pretreated with adrenocorticotrophin in lipoprotein poor media resulted in a time- and concentration-dependent ...
MAHAFFEE, D., GWYNNE, J.
core +1 more source
Isolation and characterization of a phospholipid transfer protein (LTP-II) from human plasma.
In this report we have described the purification of a human plasma phospholipid transfer protein, designated LTP-II, which displayed the following characteristics: i) facilitated both the exchange and net mass transfer of lipoprotein phospholipids; ii ...
J H Tollefson, S Ravnik, J J Albers
doaj +1 more source
We have previously shown that very low density lipoproteins (VLDL, Sf 60–400) from subjects with type IV hyperlipoproteinemia (HTG-VLDL) will induce appreciable cholesteryl ester accumulation in cultured macrophages (J774A.1).
Stewart C. Whitman +4 more
doaj +1 more source
Cholesteryl ester transfer to low density lipoproteins (LDL) was achieved either by incubation of a cholesteryl ester-rich lipid microemulsion with whole plasma or by incubation of the cholesteryl ester-rich microemulsion with lipoprotein-free plasma and LDL.
I F, Craig +6 more
openaire +2 more sources
In diabetic kidney disease, elevated podocyte ANGPTL4 is linked to reduced TFEB nuclear localization and compromised lysosomal degradative function. These changes impair podocyte lipophagy and promote lipid‐droplet accumulation and podocyte injury, which may contribute to renal injury progression.
Xiaojing Liu +7 more
wiley +1 more source
Cholesteryl ester hydrolysis in J774 macrophages occurs in the cytoplasm and lysosomes
The relationship of cholesteryl ester hydrolysis to the physical state of the cholesteryl ester in J774 murine macrophages was explored in cells induced to store cholesteryl esters either in anisotropic (ordered) inclusions or isotropic (liquid ...
Stewart J. Avart +3 more
doaj +1 more source
Resolution pharmacology is an emerging strategy to tackle inflammatory pathologies. Bioinspired meroterpenoids induce a lipid mediator class switch toward inflammation resolution in vitro and in vivo by targeting key nodes in lipid mediator biosynthesis and neutral lipid dynamics.
Lorenz Waltl +20 more
wiley +1 more source

