Results 31 to 40 of about 1,765,782 (294)

Rat plasma lipoproteins: re-evaluation of a lipoprotein system in an animal devoid of cholesteryl ester transfer activity

open access: yesJournal of Lipid Research, 1982
Plasma lipoproteins from male rats were isolated by rate zonal centrifugation. Four lipoproteins were identified: VLDL, LDL, HDL1, and HDL2. LDL, HLD1, and some HDL2 distributed within the salt density interval of 1.006-1.085 g/ml, while HDL2 was found ...
Y Oschry, S Eisenberg
doaj   +1 more source

Use of fluorescent cholesteryl ester microemulsions in cholesteryl ester transfer protein assays

open access: yesJournal of Lipid Research, 1993
In the present report we describe a simple and practical method to assess CETP activity in a defined system by use of microemulsions containing a fluorescent cholesteryl ester analog. The microemulsions are stable, simple to prepare, and can be made to defined composition.
CL Bisgaier   +4 more
openaire   +3 more sources

Cholesteryl ester storage disease: review of the findings in 135 reported patients with an underdiagnosed disease.

open access: yesJournal of Hepatology, 2013
Cholesteryl ester storage disease (CESD) is caused by deficient lysosomal acid lipase (LAL) activity, predominantly resulting in cholesteryl ester (CE) accumulation, particularly in the liver, spleen, and macrophages throughout the body.
Donna L. Bernstein   +3 more
semanticscholar   +1 more source

Cholesterol metabolism is altered by hydrolytic metabolites of prostacyclin in arterial smooth muscle cells.

open access: yesJournal of Lipid Research, 1988
Cholesteryl esters are the major lipids that accumulate in arteries during atherogenesis. The mechanisms responsible for this lipid accretion have not been completely defined.
O R Etingin, B B Weksler, D P Hajjar
doaj   +1 more source

Cholesteryl esterase and cholesteryl ester pools in corpus luteum

open access: yesJournal of Lipid Research, 1968
Cholesteryl esterase activity has been demonstrated in the corpus luteum of the rat and the cow. The hydrolytic activity in bovine corpora lutea shows two pH optima, and is distributed throughout the particulate and supernatant fractions of the tissue. The greatest activity is present in the 5000 g pellet.
J.R.T. Coutts, D.A. Stansfield
openaire   +3 more sources

Is hypertriglyceridemic very low density lipoprotein a precursor of normal low density lipoprotein?

open access: yesJournal of Lipid Research, 1985
The precursor-product relationship of very low density (VLDL) and low density lipoproteins (LDL) was studied. VLDL obtained from normal (NTG) and hypertriglyceridemic (HTG) subjects was fractionated by zonal ultracentrifugation and subjected to in vitro ...
Y Oschry   +3 more
doaj   +1 more source

Structural basis of transfer between lipoproteins by cholesteryl ester transfer protein

open access: yesNature Chemical Biology, 2012
Human cholesteryl ester transfer protein (CETP) mediates the net transfer of cholesteryl ester mass from atheroprotective high-density lipoproteins to atherogenic low-density lipoproteins by an unknown mechanism.
Lei Zhang   +18 more
semanticscholar   +1 more source

Specificity of lipid transfer protein for molecular species of cholesteryl ester.

open access: yesJournal of Lipid Research, 1988
The capacity of the plasma-derived lipid transfer protein to facilitate the transfer of various cholesteryl ester species has been investigated. Four different molecular species of cholesteryl ester were incorporated into either reconstituted high ...
R E Morton
doaj   +1 more source

Crystal Structures of Cholesteryl Ester Transfer Protein in Complex with Inhibitors

open access: yesJournal of Biological Chemistry, 2012
Background: Human cholesteryl ester transfer protein (CETP) transfers cholesteryl esters from high-density to low-density lipoprotein particles. Results: Crystallographic, mutagenesis, and biochemical studies illuminated inhibition mechanisms of CETP by ...
Shenping Liu   +8 more
semanticscholar   +1 more source

Mechanism of the defect in cholesteryl ester clearance from macrophages of atherosclerosis-susceptible White Carneau pigeons.

open access: yesJournal of Lipid Research, 1994
Recent studies from our laboratory (Yancey, P.G., and R. W. St. Clair. 1992. Arterioscler. Thromb. 12: 1291-1304) have shown that cultured peritoneal macrophages from White Carneau (WC) pigeons clear cholesteryl esters at a slower rate than do ...
P G Yancey, R W St Clair
doaj   +1 more source

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