Results 31 to 40 of about 1,765,782 (294)
Plasma lipoproteins from male rats were isolated by rate zonal centrifugation. Four lipoproteins were identified: VLDL, LDL, HDL1, and HDL2. LDL, HLD1, and some HDL2 distributed within the salt density interval of 1.006-1.085 g/ml, while HDL2 was found ...
Y Oschry, S Eisenberg
doaj +1 more source
Use of fluorescent cholesteryl ester microemulsions in cholesteryl ester transfer protein assays
In the present report we describe a simple and practical method to assess CETP activity in a defined system by use of microemulsions containing a fluorescent cholesteryl ester analog. The microemulsions are stable, simple to prepare, and can be made to defined composition.
CL Bisgaier +4 more
openaire +3 more sources
Cholesteryl ester storage disease (CESD) is caused by deficient lysosomal acid lipase (LAL) activity, predominantly resulting in cholesteryl ester (CE) accumulation, particularly in the liver, spleen, and macrophages throughout the body.
Donna L. Bernstein +3 more
semanticscholar +1 more source
Cholesteryl esters are the major lipids that accumulate in arteries during atherogenesis. The mechanisms responsible for this lipid accretion have not been completely defined.
O R Etingin, B B Weksler, D P Hajjar
doaj +1 more source
Cholesteryl esterase and cholesteryl ester pools in corpus luteum
Cholesteryl esterase activity has been demonstrated in the corpus luteum of the rat and the cow. The hydrolytic activity in bovine corpora lutea shows two pH optima, and is distributed throughout the particulate and supernatant fractions of the tissue. The greatest activity is present in the 5000 g pellet.
J.R.T. Coutts, D.A. Stansfield
openaire +3 more sources
Is hypertriglyceridemic very low density lipoprotein a precursor of normal low density lipoprotein?
The precursor-product relationship of very low density (VLDL) and low density lipoproteins (LDL) was studied. VLDL obtained from normal (NTG) and hypertriglyceridemic (HTG) subjects was fractionated by zonal ultracentrifugation and subjected to in vitro ...
Y Oschry +3 more
doaj +1 more source
Structural basis of transfer between lipoproteins by cholesteryl ester transfer protein
Human cholesteryl ester transfer protein (CETP) mediates the net transfer of cholesteryl ester mass from atheroprotective high-density lipoproteins to atherogenic low-density lipoproteins by an unknown mechanism.
Lei Zhang +18 more
semanticscholar +1 more source
Specificity of lipid transfer protein for molecular species of cholesteryl ester.
The capacity of the plasma-derived lipid transfer protein to facilitate the transfer of various cholesteryl ester species has been investigated. Four different molecular species of cholesteryl ester were incorporated into either reconstituted high ...
R E Morton
doaj +1 more source
Crystal Structures of Cholesteryl Ester Transfer Protein in Complex with Inhibitors
Background: Human cholesteryl ester transfer protein (CETP) transfers cholesteryl esters from high-density to low-density lipoprotein particles. Results: Crystallographic, mutagenesis, and biochemical studies illuminated inhibition mechanisms of CETP by ...
Shenping Liu +8 more
semanticscholar +1 more source
Recent studies from our laboratory (Yancey, P.G., and R. W. St. Clair. 1992. Arterioscler. Thromb. 12: 1291-1304) have shown that cultured peritoneal macrophages from White Carneau (WC) pigeons clear cholesteryl esters at a slower rate than do ...
P G Yancey, R W St Clair
doaj +1 more source

