Results 21 to 30 of about 40,044 (239)

Phagocytosis of cholesteryl ester is amplified in diabetic mouse macrophages and is largely mediated by CD36 and SR-A. [PDF]

PLoS ONE, 2007
Type 2 diabetes (T2D) is associated with accelerated atherosclerosis, which accounts for approximately 75% of all diabetes-related deaths. Here we investigate the link between diabetes and macrophage cholesteryl ester accumulation.
Christopher B Guest, Matthew E Hartman, Jason C O'Connor, Kenneth S Chakour, Ali A Sovari, Gregory G Freund   +5 more
doaj   +1 more source

Progesterone blocks intracellular translocation of free cholesterol derived from cholesteryl ester in macrophages.

Journal of Lipid Research, 1995
Macrophage foam cells must accommodate continuing fluxes of free cholesterol in spite of a greatly expanded store of cholesteryl ester. Though endogenous free cholesterol synthesis is suppressed, free cholesterol continues to enter the cell via ...
T Mazzone, M Krishna, Y Lange
doaj   +1 more source

Liver Transplantation to Provide Low-Density-Lipoprotein Receptors and Lower Plasma Cholesterol in a Child with Homozygous Familial Hypercholesterolemia [PDF]

, 1984
A six-year-old girl with severe hypercholesterolemia and atherosclerosis had two defective genes at the low-density-lipoprotein (LDL) receptor locus, as determined by biochemical studies of cultured fibroblasts.
Cummings, David W. Bilheimer, Goldstein, Joseph L. Goldstein, Michael S. Brown, Pittman, Schneider, Schneider, Scott M. Grundy, Thomas E. Starzl   +9 more
core   +1 more source

Role of the neutral lipid accessible pool in the regulation of secretion of apoB-100 lipoprotein particles by HepG2 cells.

Journal of Lipid Research, 1995
The rate of secretion of apoB-100-containing lipoprotein particles by HepG2 cells is determined to an important extent by post-translational mechanisms, the mass of neutral lipids clearly playing a role in this process.
R.K. Avramoglu, K Cianflone, A.D. Sniderman   +2 more
doaj   +1 more source

Bolstering cholesteryl ester hydrolysis in liver: A hepatocyte-targeting gene delivery strategy for potential alleviation of atherosclerosis [PDF]

, 2017
Current atherosclerosis treatment strategies primarily focus on limiting further cholesteryl esters (CE) accumulation by reducing endogenous synthesis of cholesterol in the liver.
Ghosh, Shobha, He, Hongliang, Korzun, William J., Lancina, Michael G., III, Wang, Jing, Yang, Hu   +5 more
core   +2 more sources

Cholesteryl ester-rich microemulsions: stable protein-free analogs of low density lipoproteins.

Journal of Lipid Research, 1982
A method has been devised for the preparation of stable lipid microemulsions containing cholesterol, cholesteryl ester, phosphatidylcholine, and trioleoylglycerol in the relative molar ratios found in low density lipoproteins.
D P Via, I F Craig, G W Jacobs, W B Van Winkle, S C Charlton, A M Gotto, Jr, L C Smith   +6 more
doaj   +1 more source

Use of fluorescent cholesteryl ester microemulsions in cholesteryl ester transfer protein assays

Journal of Lipid Research, 1993
In the present report we describe a simple and practical method to assess CETP activity in a defined system by use of microemulsions containing a fluorescent cholesteryl ester analog. The microemulsions are stable, simple to prepare, and can be made to defined composition.
CL Bisgaier, LL Minton, AD Essenburg, A White, R Homan   +4 more
openaire   +3 more sources

Polysaccharide-based self-assembling nanohydrogels: An overview on 25-years research on pullulan [PDF]

, 2015
The aim of this overview is to review the evolution of the studies carried out, during more than 25 years, on nanohydrogels obtained by self-assembling of pullulan (PUL) using several hydrophobization strategies.
ALHAIQUE, Franco, COVIELLO, Tommasina, DI MEO, Chiara, MATRICARDI, PIETRO, MONTANARI, ELITA   +4 more
core   +1 more source

Rat plasma lipoproteins: re-evaluation of a lipoprotein system in an animal devoid of cholesteryl ester transfer activity

Journal of Lipid Research, 1982
Plasma lipoproteins from male rats were isolated by rate zonal centrifugation. Four lipoproteins were identified: VLDL, LDL, HDL1, and HDL2. LDL, HLD1, and some HDL2 distributed within the salt density interval of 1.006-1.085 g/ml, while HDL2 was found ...
Y Oschry, S Eisenberg
doaj   +1 more source

Cholesterol metabolism is altered by hydrolytic metabolites of prostacyclin in arterial smooth muscle cells.

Journal of Lipid Research, 1988
Cholesteryl esters are the major lipids that accumulate in arteries during atherogenesis. The mechanisms responsible for this lipid accretion have not been completely defined.
O R Etingin, B B Weksler, D P Hajjar
doaj   +1 more source