Role of cholesteryl ester transfer protein in reverse cholesterol transport [PDF]
Clinical Cardiology, 1991 Cholesteryl ester transfer protein (CETP) and apolipoprotein E (apo E) play important roles in reverse cholesterol transport in humans. CETP transfers cholesteryl ester (CE) from high-density lipoprotein (HDL) to other lipoproteins, mainly very low-density lipoprotein (VLDL) remnants, which provide a vehicle for the delivery of HDL-derived CE to the ...
R Mcpherson
exaly +3 more sources
Changes in High-Density Lipoprotein Cholesterol and Risks of Cardiovascular Events: A from the PICASSO Trial [PDF]
Journal of Stroke, 2020 Background and purpose Whether pharmacologically altered high-density lipoprotein cholesterol (HDL-C) affects the risk of cardiovascular events is unknown.
Eun-Jae Lee +25 more
doaj +1 more source
Cholesterol Ester Transfer Protein Inhibitor Review [PDF]
Hospital Pharmacy, 2017 Treatment of blood cholesterol is part of a strategy to lower atherosclerotic cardiovascular (ASCVD) risk. While use of HMG-CoA reductase inhibitors to modify cholesterol levels is the primary means of lowering the risk of an ASCVD event, residual risk remains.
Jerry, Hu, Scot, Walker
openaire +2 more sources
Metabolism of PLTP, CETP, and LCAT on multiple HDL sizes using the Orbitrap Fusion Lumos
JCI Insight, 2021 Recent in vivo tracer studies demonstrated that targeted mass spectrometry (MS) on the Q Exactive Orbitrap could determine the metabolism of HDL proteins 100s-fold less abundant than apolipoprotein A1 (APOA1).
Sasha A. Singh +6 more
doaj +1 more source
Structure and Function of Cholesteryl Ester Transfer Protein in Cholesterol Transferring [PDF]
Biophysical Journal, 2013 Human cholesteryl ester mass can be transferred from atheroprotective high-density lipoproteins (HDL) to atherogenic low-density lipoproteins (LDL) by cholesteryl ester transfer protein (CETP), resulting higher probability of cardiovascular diseases. Finding out the mechanism of CETP in CE transferring would be an important basis and key step toward ...
Zhang, Lei, Tong, Huimin, Ren, Gang
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Journal of Lipid Research, 1985 The effect of lipid transfer proteins on the exchange and transfer of cholesteryl esters from rat plasma HDL2 to human very low (VLDL) and low density (LDL) lipoprotein populations was studied.
S Eisenberg
doaj +1 more source
High-Density Lipoprotein Modifications: A Pathological Consequence or Cause of Disease Progression?
Biomedicines, 2020 High-density lipoprotein (HDL) is well-known for its cardioprotective effects, as it possesses anti-inflammatory, anti-oxidative, anti-thrombotic, and cytoprotective properties.
Andrea Bonnin Márquez +2 more
doaj +1 more source
The combined effects of cholesteryl ester transfer protein (CETP) TaqIB gene polymorphism and canola, sesame and sesame-canola oils consumption on metabolic response in patients with diabetes and healthy people [PDF]
Journal of Cardiovascular and Thoracic Research, 2020 Introduction: Cholesteryl ester transfer protein (CETP) is a key regulating enzyme in the lipid metabolism pathway, and its gene polymorphism may be a candidate for modulating the metabolic responses to dietary intervention.
Nahid Ramezani-Jolfaie +10 more
doaj +1 more source
Effect of unesterified cholesterol on the activity of cholesteryl ester transfer protein [PDF]
Biochemical Journal, 1994 Cholesteryl ester transfer protein (CETP) catalyses the transfer of cholesteryl ester from high-density lipoprotein to triacylglycerol-rich lipoproteins and the transfer of triacylglycerols in the reverse direction. The activity of CETP has been studied using a continuous fluorescence assay which measures the excimer fluorescence of cholesteryl 1 ...
O V, Rajaram, R Y, Chan, W H, Sawyer
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Journal of Lipid Research, 1992 The access of enzymes and lipid transfer proteins to neutral lipids located predominantly in the core compartment of lipoproteins may be determined to some degree by the solubility of the neutral lipids in the surface monolayer of phospholipid.
QT Li, WH Sawyer
doaj +1 more source